PMID- 26058370
OWN - NLM
STAT- MEDLINE
DCOM- 20160912
LR  - 20151208
IS  - 1098-8785 (Electronic)
IS  - 0735-1631 (Linking)
VI  - 32
IP  - 13
DP  - 2015 Nov
TI  - Apgar Score at 5 Minutes Is Associated with Mortality in Extremely Preterm 
      Infants Even after Transfer to an All Referral NICU.
PG  - 1268-72
LID - 10.1055/s-0035-1554803 [doi]
AB  - OBJECTIVE: The Apgar score has been shown to have utility in predicting mortality 
      in the extremely preterm infant in delivery hospital populations, where most 
      mortality occurs within 12 hours of birth. We tested the hypothesis that the 5 
      minute Apgar score would remain associated with mortality in extremely preterm 
      infants after transfer from the delivery hospital to an all referral neonatal 
      intensive care unit at an average age of 10 days. STUDY DESIGN: A retrospective 
      analysis of 454 infants born at < 27 weeks gestation. RESULTS: The median Apgar 
      score was 3 at 1 minute (interquartile range [IQR] 2-6) and 6 at 5 minutes (IQR 
      4-7). The Apgar score increased from 1 to 5 minutes by 2.0 +/- 1.7 (p < 0.001). In 
      logistic regression modeling, an Apgar score of < 5 at 5 minutes was associated 
      with an increased mortality (odds ratio 1.76 [95% confidence interval 1.06-2.94], 
      p < 0.05), but not morbidities. CONCLUSION: Infants born at < 27 weeks gestation 
      admitted to an all referral children's hospital at a mean age of 10 days with a 5 
      minute Apgar < 5 are at an increased risk of mortality. Our findings continue to 
      support the importance of the Apgar score given at delivery even in the extremely 
      preterm infant referred to a nondelivery children's hospital.
CI  - Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.
FAU - Bartman, Thomas
AU  - Bartman T
AD  - Division of Neonatology, Department of Pediatrics, The Ohio State University, 
      Columbus, Ohio.
FAU - Bapat, Roopali
AU  - Bapat R
AD  - Division of Neonatology, Department of Pediatrics, The Ohio State University, 
      Columbus, Ohio.
FAU - Martin, Elizabeth M
AU  - Martin EM
AD  - Small Baby Program, Nationwide Children's Hospital, Columbus, Ohio.
FAU - Shepherd, Edward G
AU  - Shepherd EG
AD  - Division of Neonatology, Department of Pediatrics, The Ohio State University, 
      Columbus, Ohio.
FAU - Nelin, Leif D
AU  - Nelin LD
AD  - Division of Neonatology, Department of Pediatrics, The Ohio State University, 
      Columbus, Ohio.
FAU - Reber, Kristina M
AU  - Reber KM
AD  - Division of Neonatology, Department of Pediatrics, The Ohio State University, 
      Columbus, Ohio.
LA  - eng
PT  - Journal Article
DEP - 20150609
PL  - United States
TA  - Am J Perinatol
JT  - American journal of perinatology
JID - 8405212
SB  - IM
MH  - *Apgar Score
MH  - Cerebral Ventricles
MH  - Cohort Studies
MH  - Ductus Arteriosus, Patent/epidemiology
MH  - Enterocolitis, Necrotizing/epidemiology
MH  - Female
MH  - Hospitals, Pediatric
MH  - Humans
MH  - Infant
MH  - *Infant Mortality
MH  - Infant, Extremely Low Birth Weight
MH  - Infant, Extremely Premature
MH  - Infant, Newborn
MH  - Intensive Care Units, Neonatal
MH  - Intracranial Hemorrhages/epidemiology
MH  - Logistic Models
MH  - Male
MH  - Odds Ratio
MH  - Patient Transfer
MH  - Prognosis
MH  - Referral and Consultation
MH  - Retrospective Studies
EDAT- 2015/06/11 06:00
MHDA- 2016/09/13 06:00
CRDT- 2015/06/11 06:00
PHST- 2015/06/11 06:00 [entrez]
PHST- 2015/06/11 06:00 [pubmed]
PHST- 2016/09/13 06:00 [medline]
AID - 10.1055/s-0035-1554803 [doi]
PST - ppublish
SO  - Am J Perinatol. 2015 Nov;32(13):1268-72. doi: 10.1055/s-0035-1554803. Epub 2015 
      Jun 9.