PMID- 26064106 OWN - NLM STAT- PubMed-not-MEDLINE DCOM- 20150611 LR - 20201001 IS - 1687-8337 (Print) IS - 1687-8345 (Electronic) IS - 1687-8337 (Linking) VI - 2015 DP - 2015 TI - Cognitive Function and Salivary DHEA Levels in Physically Active Elderly African American Women. PG - 219046 LID - 10.1155/2015/219046 [doi] LID - 219046 AB - Serum and plasma dehydroepiandrosterone sulfate (DHEAS) concentration has been associated with several health parameters associated with aging including cognitive function, bone mineral density, and muscular strength. However, the effectiveness of salivary DHEA for the prediction of cognitive function, bone mineral density, and muscular strength in older adults is currently unknown. Thirty elderly African American females provided early morning salivary samples and DHEA levels were determined using a commercially available immunoassay. Participants completed testing for psychomotor and executive function via Trail Making Tests (TMT) A and B, respectively. Bone ultrasound attenuation (BUA) was used to bone density and an isometric mid-thigh pull (IMTP) was used to determine isometric strength. Age significantly correlated with time on TMT A (r=0.328) and B (r=0.615) but was not related to DHEA, BUA, or IMTP outcomes. Elevated DHEA was associated with longer time to completion for TMT A (chi (2) = 5.14) but not to TMT B. DHEA levels were not associated with BUA or IMTP outcomes. While elevated levels of DHEA were correlated with impaired psychomotor function, salivary DHEA is not associated with executive function, bone mineral density, or isometric strength in elderly African American women. FAU - Davis, Greggory R AU - Davis GR AUID- ORCID: 0000-0003-2410-9070 AD - School of Kinesiology, University of Louisiana at Lafayette, Lafayette, LA 70504, USA. FAU - Gallien, Gabrielle J AU - Gallien GJ AD - School of Kinesiology, University of Louisiana at Lafayette, Lafayette, LA 70504, USA. FAU - Moody, Kaitlyn M AU - Moody KM AD - School of Kinesiology, University of Louisiana at Lafayette, Lafayette, LA 70504, USA. FAU - LeBlanc, Nina R AU - LeBlanc NR AD - School of Kinesiology, University of Louisiana at Lafayette, Lafayette, LA 70504, USA. FAU - Smoak, Peter R AU - Smoak PR AD - School of Kinesiology, University of Louisiana at Lafayette, Lafayette, LA 70504, USA. FAU - Bellar, David AU - Bellar D AD - School of Kinesiology, University of Louisiana at Lafayette, Lafayette, LA 70504, USA. LA - eng PT - Journal Article DEP - 20150512 PL - Egypt TA - Int J Endocrinol JT - International journal of endocrinology JID - 101516376 PMC - PMC4443930 EDAT- 2015/06/13 06:00 MHDA- 2015/06/13 06:01 PMCR- 2015/05/12 CRDT- 2015/06/12 06:00 PHST- 2014/12/10 00:00 [received] PHST- 2015/04/16 00:00 [revised] PHST- 2015/04/23 00:00 [accepted] PHST- 2015/06/12 06:00 [entrez] PHST- 2015/06/13 06:00 [pubmed] PHST- 2015/06/13 06:01 [medline] PHST- 2015/05/12 00:00 [pmc-release] AID - 10.1155/2015/219046 [doi] PST - ppublish SO - Int J Endocrinol. 2015;2015:219046. doi: 10.1155/2015/219046. Epub 2015 May 12.