PMID- 26069752 OWN - NLM STAT- PubMed-not-MEDLINE DCOM- 20150613 LR - 20200930 IS - 2048-8505 (Print) IS - 2048-8513 (Electronic) IS - 2048-8505 (Linking) VI - 5 IP - 1 DP - 2012 Feb TI - Kidney light chain disease in patients with the acquired immunodeficiency syndrome. PG - 59-62 LID - 10.1093/ckj/sfr176 [doi] AB - Light chain deposit disease (LCDD) is a rare condition caused by deposition of overproduced monoclonal light chains and has been frequently related to multiple myeloma or lymphocytic disorders. LCDD in association with human immunodeficiency virus (HIV) has only been described twice in the literature and is thought to result from HIV direct/indirect effects on B and T-cell populations, leading to chronic immune activation with paraprotein production. We report a renal LCDD case diagnosed at autopsy in a severely immunodepressed HIV patient and analyse renal histopathology of 18 HIV patients who had an autopsy in our department between 2000 and 2010. FAU - Villaverde, Raquel Vilarino AU - Villaverde RV AD - Institute of Clinical Pathology, University Hospital, Geneva, Switzerland. FAU - Darioli, Vincent AU - Darioli V AD - Department of Internal Medicine, University Hospital, Geneva, Switzerland. FAU - Hirschel, Bernard AU - Hirschel B AD - Department of Internal Medicine, University Hospital, Geneva, Switzerland. FAU - McKee, Thomas Alexander AU - McKee TA AD - Institute of Clinical Pathology, University Hospital, Geneva, Switzerland. FAU - Lobrinus, Johannes Alexander AU - Lobrinus JA AD - Institute of Clinical Pathology, University Hospital, Geneva, Switzerland. FAU - Moll, Solange AU - Moll S AD - Institute of Clinical Pathology, University Hospital, Geneva, Switzerland. LA - eng PT - Case Reports PL - England TA - Clin Kidney J JT - Clinical kidney journal JID - 101579321 PMC - PMC4400465 OTO - NOTNLM OT - HIV OT - light chain deposit disease (LCDD) OT - renal pathology EDAT- 2012/02/01 00:00 MHDA- 2012/02/01 00:01 PMCR- 2012/02/01 CRDT- 2015/06/13 06:00 PHST- 2011/11/10 00:00 [received] PHST- 2011/12/12 00:00 [accepted] PHST- 2015/06/13 06:00 [entrez] PHST- 2012/02/01 00:00 [pubmed] PHST- 2012/02/01 00:01 [medline] PHST- 2012/02/01 00:00 [pmc-release] AID - 10.1093/ckj/sfr176 [doi] PST - ppublish SO - Clin Kidney J. 2012 Feb;5(1):59-62. doi: 10.1093/ckj/sfr176.