PMID- 26078924
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20150616
LR  - 20200930
IS  - 2233-601X (Print)
IS  - 2093-6516 (Electronic)
IS  - 2233-601X (Linking)
VI  - 48
IP  - 3
DP  - 2015 Jun
TI  - Venovenous Extracorporeal Membrane Oxygenation for Postoperative Acute 
      Respiratory Distress Syndrome.
PG  - 180-6
LID - 10.5090/kjtcs.2015.48.3.180 [doi]
AB  - BACKGROUND: Extracorporeal membrane oxygenation (ECMO) has recently attracted 
      interest as a treatment for severe acute respiratory distress syndrome (ARDS). 
      However, the outcomes of this procedure in post-surgical settings have not yet 
      been characterized. In this study, we evaluated the outcomes of ECMO in patients 
      with severe postoperative ARDS. METHODS: From January 2007 to December 2012, a 
      total of 69 patients (aged 58.3+/-11.5 years, 23 females) who underwent venovenous 
      ECMO to treat severe postoperative ARDS were reviewed. Of these patients, 22 
      (31.9%) had undergone cardiothoracic surgery, 32 (46.4%) had undergone liver 
      transplantation, and 15 (21.7%) had undergone other procedures. RESULTS: 
      Thirty-four patients (49.3%) were successfully weaned from ECMO, while the other 
      35 patients (50.7%) died on ECMO support. Among the 34 patients who were 
      successfully weaned from ECMO, 21 patients (30.4%) eventually died before 
      discharge from the hospital, resulting in 13 hospital survivors (18.8%). 
      Multivariable analysis showed that the duration of pre-ECMO ventilation was a 
      significant independent predictor of death (odds ratio [OR], 2.25; 95% confidence 
      interval [CI], 1.29 to 3.90; p=0.004), whereas the concomitant use of continuous 
      venovenous hemodialysis (CVVHD) was associated with improved survival (OR, 0.55; 
      95% CI, 0.31 to 0.97; p=0.038). CONCLUSION: Although the overall survival rate of 
      patients treated with ECMO for postoperative ARDS was unfavorable, ECMO offered 
      an invaluable opportunity for survival to patients who would not have been 
      expected to survive using conventional therapy. CVVHD may be beneficial in 
      improving the outcomes of such patients, whereas a prolonged duration of pre-ECMO 
      ventilator support was associated with poor survival.
FAU - Seo, Dong Ju
AU  - Seo DJ
AD  - Department of Thoracic and Cardiovascular Surgery, Asan Medical Center, 
      University of Ulsan College of Medicine.
FAU - Yoo, Jae Suk
AU  - Yoo JS
AD  - Department of Thoracic and Cardiovascular Surgery, Asan Medical Center, 
      University of Ulsan College of Medicine.
FAU - Kim, Joon Bum
AU  - Kim JB
AD  - Department of Thoracic and Cardiovascular Surgery, Asan Medical Center, 
      University of Ulsan College of Medicine.
FAU - Jung, Sung-Ho
AU  - Jung SH
AD  - Department of Thoracic and Cardiovascular Surgery, Asan Medical Center, 
      University of Ulsan College of Medicine.
FAU - Choo, Suk Jung
AU  - Choo SJ
AD  - Department of Thoracic and Cardiovascular Surgery, Asan Medical Center, 
      University of Ulsan College of Medicine.
FAU - Chung, Cheol Hyun
AU  - Chung CH
AD  - Department of Thoracic and Cardiovascular Surgery, Asan Medical Center, 
      University of Ulsan College of Medicine.
FAU - Lee, Jae Won
AU  - Lee JW
AD  - Department of Thoracic and Cardiovascular Surgery, Asan Medical Center, 
      University of Ulsan College of Medicine.
LA  - eng
PT  - Journal Article
DEP - 20150605
PL  - Korea (South)
TA  - Korean J Thorac Cardiovasc Surg
JT  - The Korean journal of thoracic and cardiovascular surgery
JID - 101563922
PMC - PMC4463224
OTO - NOTNLM
OT  - Acute respiratory distress syndrome (ARDS)
OT  - Extracorporeal membrane oxygenation
OT  - Prognosis
OT  - Survival
EDAT- 2015/06/17 06:00
MHDA- 2015/06/17 06:01
PMCR- 2015/06/01
CRDT- 2015/06/17 06:00
PHST- 2014/09/02 00:00 [received]
PHST- 2014/10/22 00:00 [revised]
PHST- 2014/10/27 00:00 [accepted]
PHST- 2015/06/17 06:00 [entrez]
PHST- 2015/06/17 06:00 [pubmed]
PHST- 2015/06/17 06:01 [medline]
PHST- 2015/06/01 00:00 [pmc-release]
AID - kjtcv-48-180 [pii]
AID - 10.5090/kjtcs.2015.48.3.180 [doi]
PST - ppublish
SO  - Korean J Thorac Cardiovasc Surg. 2015 Jun;48(3):180-6. doi: 
      10.5090/kjtcs.2015.48.3.180. Epub 2015 Jun 5.