PMID- 26082067
OWN - NLM
STAT- MEDLINE
DCOM- 20160324
LR  - 20220331
IS  - 2045-2322 (Electronic)
IS  - 2045-2322 (Linking)
VI  - 5
DP  - 2015 Jun 17
TI  - Cancer risk among patients with type 2 diabetes mellitus: a population-based 
      prospective study in China.
PG  - 11503
LID - 10.1038/srep11503 [doi]
LID - 11503
AB  - Evidence indicates an increased cancer risk among type 2 diabetes mellitus (T2DM) 
      patients, yet studies in mainland China are scarce. Based on Diabetes 
      Surveillance System linking to Cancer Surveillance System of Zhejiang Province in 
      China, we explored the cancer risk among T2DM patients. Totally, 327,268 T2DM 
      patients were identified and followed from January 1, 2007 to December 31, 2013. 
      Standardized incidence ratios (SIRs) with 95% confidence intervals (CIs) were 
      reported. Overall cancer risk was found significantly increased with an SIR of 
      1.15 (95% CI 1.12-1.19) and 1.25 (95% CI 1.21-1.30) in males and females, 
      respectively. Regarding specific cancer sites, risks of liver, colon, rectum, 
      pancreas, and kidney were significantly increased with SIRs of 1.26 (95% CI 
      1.16-1.36), 1.47 (95% CI 1.29-1.67), 1.25 (95% CI 1.09-1.43), 2.81 (95% CI 
      2.50-3.16) and 1.61 (95% CI 1.28-2.03) in males, 1.53 (95% CI 1.35-1.73), 1.33 
      (95% CI 1.15-1.54), 1.29 (95% CI 1.10-1.51), 3.62 (95% CI 3.20-4.09) and 1.71 
      (95% CI 1.28-2.29) in females, respectively. A significant increased SIR was 
      noted for prostate (1.80, 95% CI 1.58-2.06). Significant increased SIRs for lung 
      (1.32, 95% CI 1.20-1.44) and stomach (1.16, 95% CI 1.03-1.30) were observed in 
      females. We suggested an increased cancer risk among T2DM patients.
FAU - Wang, Meng
AU  - Wang M
AD  - Zhejiang Provincial Center for Disease Control and Prevention, 3399 Binsheng 
      Road, Hangzhou 310051, China.
FAU - Hu, Ru-Ying
AU  - Hu RY
AD  - Zhejiang Provincial Center for Disease Control and Prevention, 3399 Binsheng 
      Road, Hangzhou 310051, China.
FAU - Wu, Hai-Bin
AU  - Wu HB
AD  - Zhejiang Provincial Center for Disease Control and Prevention, 3399 Binsheng 
      Road, Hangzhou 310051, China.
FAU - Pan, Jin
AU  - Pan J
AD  - Zhejiang Provincial Center for Disease Control and Prevention, 3399 Binsheng 
      Road, Hangzhou 310051, China.
FAU - Gong, Wei-Wei
AU  - Gong WW
AD  - Zhejiang Provincial Center for Disease Control and Prevention, 3399 Binsheng 
      Road, Hangzhou 310051, China.
FAU - Guo, Li-Hua
AU  - Guo LH
AD  - Zhejiang Provincial Center for Disease Control and Prevention, 3399 Binsheng 
      Road, Hangzhou 310051, China.
FAU - Zhong, Jie-Ming
AU  - Zhong JM
AD  - Zhejiang Provincial Center for Disease Control and Prevention, 3399 Binsheng 
      Road, Hangzhou 310051, China.
FAU - Fei, Fang-Rong
AU  - Fei FR
AD  - Zhejiang Provincial Center for Disease Control and Prevention, 3399 Binsheng 
      Road, Hangzhou 310051, China.
FAU - Yu, Min
AU  - Yu M
AD  - Zhejiang Provincial Center for Disease Control and Prevention, 3399 Binsheng 
      Road, Hangzhou 310051, China.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20150617
PL  - England
TA  - Sci Rep
JT  - Scientific reports
JID - 101563288
SB  - IM
MH  - Aged
MH  - China/epidemiology
MH  - Diabetes Mellitus, Type 2/*complications/*epidemiology
MH  - Female
MH  - Humans
MH  - Incidence
MH  - Male
MH  - Middle Aged
MH  - Neoplasms/*epidemiology/*etiology
MH  - *Population Surveillance
MH  - *Risk
PMC - PMC4469976
EDAT- 2015/06/18 06:00
MHDA- 2016/03/25 06:00
PMCR- 2015/06/17
CRDT- 2015/06/18 06:00
PHST- 2015/03/11 00:00 [received]
PHST- 2015/05/27 00:00 [accepted]
PHST- 2015/06/18 06:00 [entrez]
PHST- 2015/06/18 06:00 [pubmed]
PHST- 2016/03/25 06:00 [medline]
PHST- 2015/06/17 00:00 [pmc-release]
AID - srep11503 [pii]
AID - 10.1038/srep11503 [doi]
PST - epublish
SO  - Sci Rep. 2015 Jun 17;5:11503. doi: 10.1038/srep11503.