PMID- 2609331
OWN - NLM
STAT- MEDLINE
DCOM- 19900220
LR  - 20190727
IS  - 0040-8727 (Print)
IS  - 0040-8727 (Linking)
VI  - 159
IP  - 2
DP  - 1989 Oct
TI  - Increased hexokinase activity in fetuses of rats developed under maternal 
      hyperglycemia.
PG  - 139-45
AB  - Hepatic and diaphragmatic hexokinase (HK) activities increased in fetuses of rats 
      developed under maternal hyperglycemic conditions, compared to those in normal 
      controls. In those organs, Type I and Type II hexokinase isozymes were detected 
      by electrophoresis and densitometry with a chromatoscanner. Densitometric peak 
      that corresponded to hepatic and diaphragmatic Type II hexokinase was also 
      increased in the fetuses developed under hyperglycemia, compared to that of 
      normal fetuses. These findings suggest that in the fetal liver, where significant 
      activity of Type IV was absent, activity of Type II hexokinase varied depending 
      on physiological state such as maternal hyperglycemia.
FAU - Wako, Y
AU  - Wako Y
AD  - Laboratory of Nutrition, Faculty of Agriculture, Tohoku University, Senddi.
FAU - Suzuki, K
AU  - Suzuki K
FAU - Isobe, A
AU  - Isobe A
FAU - Kimura, S
AU  - Kimura S
LA  - eng
PT  - Journal Article
PL  - Japan
TA  - Tohoku J Exp Med
JT  - The Tohoku journal of experimental medicine
JID - 0417355
RN  - EC 2.7.1.1 (Hexokinase)
RN  - IY9XDZ35W2 (Glucose)
SB  - IM
MH  - Animals
MH  - Diabetes Mellitus, Experimental/metabolism
MH  - Female
MH  - Fetus/enzymology/*metabolism
MH  - Glucose/*metabolism
MH  - Hexokinase/metabolism
MH  - Hyperglycemia/*metabolism
MH  - *Maternal-Fetal Exchange
MH  - Pregnancy
MH  - Pregnancy in Diabetics/*metabolism
MH  - Rats
MH  - Rats, Inbred Strains
EDAT- 1989/10/01 00:00
MHDA- 1989/10/01 00:01
CRDT- 1989/10/01 00:00
PHST- 1989/10/01 00:00 [pubmed]
PHST- 1989/10/01 00:01 [medline]
PHST- 1989/10/01 00:00 [entrez]
AID - 10.1620/tjem.159.139 [doi]
PST - ppublish
SO  - Tohoku J Exp Med. 1989 Oct;159(2):139-45. doi: 10.1620/tjem.159.139.