PMID- 26094035
OWN - NLM
STAT- MEDLINE
DCOM- 20160302
LR  - 20191210
IS  - 1090-2414 (Electronic)
IS  - 0147-6513 (Linking)
VI  - 120
DP  - 2015 Oct
TI  - Ecological risk assessment of silicon dioxide nanoparticles in a freshwater fish 
      Labeo rohita: Hematology, ionoregulation and gill Na(+)/K(+) ATPase activity.
PG  - 295-302
LID - S0147-6513(15)00255-9 [pii]
LID - 10.1016/j.ecoenv.2015.05.032 [doi]
AB  - The fate and effect of nanomaterials in the environment has raised concern about 
      their environmental risk to aquatic organisms. Silica nanoparticles (SiO2-NPs) 
      find its uses in various fields and are inevitably released into the environment. 
      However, the ecotoxicological effects of SiO2-NPs on the freshwater fish remain 
      poorly understood. The aim of this study was to evaluate the effect of different 
      concentrations (1, 5 and 25mgL(-1)) of SiO2-NPs on certain hematological, 
      ionoregulatory and enzymological profiles of a freshwater teleost fish Labeo 
      rohita. Hematological parameters such as hemoglobin (Hb), hematocrit (Hct), red 
      blood cells (RBC), white blood cells (WBC), mean corpuscular volume (MCV), mean 
      corpuscular hemoglobin (MCH) and mean corpuscular hemoglobin concentration (MCHC) 
      values were altered in SiO2-NPs treated groups. Likewise, plasma electrolytes 
      such as plasma sodium (Na(+)), potassium (K(+)) and chloride (Cl(-)) levels and 
      Na(+)/K(+) ATPase activity in gill of SiO2-NPs treated groups were altered in all 
      concentrations throughout the study period (96h). The alterations of these 
      parameters were found to be dependent on dose and exposure period. The results of 
      the present study indicate that the alterations of these parameters may relate to 
      physiological stress system to SiO2-NPs toxicity and also demonstrate that 
      manufactured metal oxide NPs in aquatic environment may affect the health 
      condition of the aquatic organisms.
CI  - Copyright (c) 2015 Elsevier Inc. All rights reserved.
FAU - Krishna Priya, K
AU  - Krishna Priya K
AD  - Unit of Toxicology, Department of Zoology, School of Life Sciences, Bharathiar 
      University, Coimbatore 641046, Tamil Nadu, India.
FAU - Ramesh, M
AU  - Ramesh M
AD  - Unit of Toxicology, Department of Zoology, School of Life Sciences, Bharathiar 
      University, Coimbatore 641046, Tamil Nadu, India.
FAU - Saravanan, M
AU  - Saravanan M
AD  - Unit of Toxicology, Department of Zoology, School of Life Sciences, Bharathiar 
      University, Coimbatore 641046, Tamil Nadu, India.
FAU - Ponpandian, N
AU  - Ponpandian N
AD  - Department of Nanoscience and Technology, Bharathiar University, Coimbatore 
      641046, Tamil Nadu, India.
LA  - eng
PT  - Journal Article
DEP - 20150619
PL  - Netherlands
TA  - Ecotoxicol Environ Saf
JT  - Ecotoxicology and environmental safety
JID - 7805381
RN  - 0 (Hemoglobins)
RN  - 0 (Water Pollutants, Chemical)
RN  - 7631-86-9 (Silicon Dioxide)
RN  - 9NEZ333N27 (Sodium)
RN  - EC 7.2.2.13 (Sodium-Potassium-Exchanging ATPase)
RN  - RWP5GA015D (Potassium)
SB  - IM
MH  - Animals
MH  - Cyprinidae/*metabolism
MH  - Erythrocyte Indices
MH  - Erythrocytes
MH  - Fresh Water/*chemistry
MH  - Gills/*drug effects/enzymology
MH  - Hematocrit
MH  - Hemoglobins/metabolism
MH  - Leukocyte Count
MH  - Nanoparticles/chemistry/*toxicity
MH  - Potassium/blood
MH  - Risk Assessment
MH  - Silicon Dioxide/chemistry/*toxicity
MH  - Sodium/blood
MH  - Sodium-Potassium-Exchanging ATPase/*metabolism
MH  - Toxicity Tests, Acute
MH  - Water Pollutants, Chemical/chemistry/toxicity
OTO - NOTNLM
OT  - Gill Na(+)/K(+) ATPase
OT  - Hematology
OT  - Ionoregulation
OT  - Labeo rohita
OT  - SiO(2)-nanoparticles
OT  - Toxicology
EDAT- 2015/06/22 06:00
MHDA- 2016/03/05 06:00
CRDT- 2015/06/22 06:00
PHST- 2014/10/14 00:00 [received]
PHST- 2015/05/18 00:00 [revised]
PHST- 2015/05/19 00:00 [accepted]
PHST- 2015/06/22 06:00 [entrez]
PHST- 2015/06/22 06:00 [pubmed]
PHST- 2016/03/05 06:00 [medline]
AID - S0147-6513(15)00255-9 [pii]
AID - 10.1016/j.ecoenv.2015.05.032 [doi]
PST - ppublish
SO  - Ecotoxicol Environ Saf. 2015 Oct;120:295-302. doi: 10.1016/j.ecoenv.2015.05.032. 
      Epub 2015 Jun 19.