PMID- 26100310
OWN - NLM
STAT- MEDLINE
DCOM- 20150812
LR  - 20150623
IS  - 0231-424X (Print)
IS  - 0231-424X (Linking)
VI  - 102
IP  - 2
DP  - 2015 Jun
TI  - Prediction of myocardial tissue loss by quantitative densitometric myocardial 
      blush parameters following ST-elevation myocardial infarction.
PG  - 206-15
LID - 10.1556/036.102.2015.2.11 [doi]
AB  - Tissue level myocardial perfusion is one of the most important prognostic factors 
      after successful recanalisation of the occluded coronary artery in patients 
      suffering acute ST elevation myocardial infarction (STEMI). The primary objective 
      of the present study was to examine the relationship between videodensitometric 
      myocardial perfusion parameters as assessed on coronary angiograms directly 
      following successful recanalization therapy and magnetic resonance imaging 
      (MRI)-derived myocardial tissue loss late after STEMI. The study comprised 29 
      STEMI patients. Videodensitometric parameter G(max)/T(max) was calculated to 
      characterize myocardial perfusion, derived from the plateau of grey-level 
      intensity (G(max)), divided by the time-to-peak intensity (Tmax). Myocardial loss 
      index (MLI) was assessed by cardiac MRI following 376 +/- 254 days after PCI. 
      RESULTS: Significant correlations could be demonstrated between MLI and G(max) (r 
      = 0.36, p = 0.05) and G(max)/T(max) (r = 0.40, p = 0.03) using vessel masking. 
      Using receiver operating characteristic curve analysis, G(max)/T(max) < 2.17 
      predicted best MLI = 0.3, 0.4, 0.5 and 0.6 with good sensitivity and specificity 
      data, while G(max)/T(max) < 3.25 proved to have a prognostic role in the 
      prediction of MLI = 0.7. CONCLUSIONS: Selective myocardial tissue level perfusion 
      quantitative measurement method is feasible and can serve as a good predictor of 
      myocardial tissue loss following STEMI and revascularization therapy.
FAU - Sasi, V
AU  - Sasi V
AD  - Division of Invasive Cardiology, Department of Cardiology, Medical Faculty, 
      Albert Szent-Gyorgyi Clinical Center, University of Szeged , Szeged , Hungary.
FAU - Gavaller, H
AU  - Gavaller H
FAU - Kalapos, A
AU  - Kalapos A
FAU - Domsik, P
AU  - Domsik P
FAU - Nagy, F T
AU  - Nagy FT
FAU - Ungi, T
AU  - Ungi T
FAU - Ungi, I
AU  - Ungi I
FAU - Forster, T
AU  - Forster T
FAU - Nemes, Attila
AU  - Nemes A
LA  - eng
PT  - Journal Article
PL  - Hungary
TA  - Acta Physiol Hung
JT  - Acta physiologica Hungarica
JID - 8309201
SB  - IM
MH  - Aged
MH  - *Angiography, Digital Subtraction
MH  - *Coronary Angiography
MH  - *Coronary Circulation
MH  - *Densitometry
MH  - Feasibility Studies
MH  - Female
MH  - Humans
MH  - Magnetic Resonance Imaging
MH  - Male
MH  - Middle Aged
MH  - Myocardial Infarction/*diagnosis/physiopathology/therapy
MH  - Myocardial Perfusion Imaging/*methods
MH  - Myocardium/*pathology
MH  - Percutaneous Coronary Intervention
MH  - Predictive Value of Tests
MH  - Radiographic Image Interpretation, Computer-Assisted
MH  - Registries
MH  - Treatment Outcome
MH  - Video Recording
OTO - NOTNLM
OT  - blush
OT  - coronary angiography
OT  - densitometry
OT  - myocardial infarction
OT  - prediction
EDAT- 2015/06/24 06:00
MHDA- 2015/08/13 06:00
CRDT- 2015/06/24 06:00
PHST- 2015/06/24 06:00 [entrez]
PHST- 2015/06/24 06:00 [pubmed]
PHST- 2015/08/13 06:00 [medline]
AID - 10.1556/036.102.2015.2.11 [doi]
PST - ppublish
SO  - Acta Physiol Hung. 2015 Jun;102(2):206-15. doi: 10.1556/036.102.2015.2.11.