PMID- 26109023
OWN - NLM
STAT- MEDLINE
DCOM- 20160218
LR  - 20181202
IS  - 1724-6016 (Electronic)
IS  - 1120-6721 (Linking)
VI  - 25
IP  - 6
DP  - 2015 Oct 21
TI  - Correlation of spectral-domain optical coherence tomography with fundus 
      fluorescein angiography in an infant with retinal hamartomas.
PG  - e106-8
LID - 5E99A473-2B83-4A2E-9D5C-F6C813EC2F45 [pii]
LID - 10.5301/ejo.5000640 [doi]
AB  - PURPOSE: To describe the correlation between the surface morphology on 
      spectral-domain optical coherence tomography (SD-OCT) and leakage pattern on 
      fundus fluorescein angiography (FFA) in an infant with multiple retinal 
      hamartomas. METHODS: An Asian Indian female infant was found to have 2 retinal 
      lesions in the right eye and 1 in the left eye during Retcam (Clarity MSI, CA, 
      USA) screening for retinopathy of prematurity at 45 weeks postmenstrual age. 
      Spectral-domain optical coherence tomography on the hand-held OCT (Envisu 2300, 
      Bioptigen, NC, USA) and FFA on the Retcam 3 were performed under monitoring in 
      the office. RESULTS: Spectral-domain OCT detected all 3 lesions but only 1 lesion 
      was detected on FFA. While this lesion had an irregular surface with overlying 
      vitreoretinal (VR) traction on SD-OCT, the other 2 lesions not detected on FFA 
      were smooth and had no VR traction. After a follow-up to 18 months corrected age, 
      there was no change in the morphology of any of the lesions. CONCLUSIONS: It is 
      possible to characterize retinal hamartomas in infants using SD-OCT and correlate 
      them with FFA. Spectral-domain OCT examination can be used to diagnose and 
      monitor lesions even if they are not detectable on angiography.
FAU - Chidambara, Lavanya
AU  - Chidambara L
AD  - From the Narayana Nethralaya Postgraduate Institute of Ophthalmology, Bangalore - 
      India.
FAU - Jayadev, Chaitra
AU  - Jayadev C
AD  - From the Narayana Nethralaya Postgraduate Institute of Ophthalmology, Bangalore - 
      India.
FAU - Mangalesh, Shwetha
AU  - Mangalesh S
AD  - From the Narayana Nethralaya Postgraduate Institute of Ophthalmology, Bangalore - 
      India.
FAU - Sivakumar, Munusamy
AU  - Sivakumar M
AD  - From the Narayana Nethralaya Postgraduate Institute of Ophthalmology, Bangalore - 
      India.
FAU - Shetty, Bhujang
AU  - Shetty B
AD  - From the Narayana Nethralaya Postgraduate Institute of Ophthalmology, Bangalore - 
      India.
FAU - Vinekar, Anand
AU  - Vinekar A
AD  - From the Narayana Nethralaya Postgraduate Institute of Ophthalmology, Bangalore - 
      India.
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20151021
PL  - United States
TA  - Eur J Ophthalmol
JT  - European journal of ophthalmology
JID - 9110772
SB  - IM
MH  - Capillary Permeability
MH  - Female
MH  - *Fluorescein Angiography
MH  - Gestational Age
MH  - Hamartoma Syndrome, Multiple/*diagnosis
MH  - Humans
MH  - Infant
MH  - Infant, Newborn
MH  - Magnetic Resonance Imaging
MH  - Neonatal Screening
MH  - Ophthalmologic Surgical Procedures
MH  - Retinal Diseases/*diagnosis
MH  - Retinal Vessels/pathology
MH  - *Tomography, Optical Coherence/methods
MH  - Tuberous Sclerosis/diagnosis
EDAT- 2015/06/26 06:00
MHDA- 2016/02/19 06:00
CRDT- 2015/06/26 06:00
PHST- 2015/05/22 00:00 [accepted]
PHST- 2015/06/26 06:00 [entrez]
PHST- 2015/06/26 06:00 [pubmed]
PHST- 2016/02/19 06:00 [medline]
AID - 5E99A473-2B83-4A2E-9D5C-F6C813EC2F45 [pii]
AID - 10.5301/ejo.5000640 [doi]
PST - epublish
SO  - Eur J Ophthalmol. 2015 Oct 21;25(6):e106-8. doi: 10.5301/ejo.5000640.