PMID- 2612127
OWN - NLM
STAT- MEDLINE
DCOM- 19900307
LR  - 20190903
IS  - 0732-8893 (Print)
IS  - 0732-8893 (Linking)
VI  - 12
IP  - 5
DP  - 1989 Sep-Oct
TI  - Detection of staphylococcal resistance to penicillinase-resistant penicillins. A 
      comparison of two widely used disk diffusion methods.
PG  - 381-4
AB  - One hundred Staphylococcus spp. strains were used to compare the results of two 
      single potency disk diffusion methods (oxacillin and methicillin disks). The 
      NCCLS disk diffusion and dilution methods correctly categorized all strains 
      resistant to penicillinase-resistant penicillins (PRPs). The SHOWA disk method 
      (Showa Yakuhin Kako Co., Ltd., Japan) produced false-susceptible results with 
      approximately half of the PRP-resistant strains. The errors by the SHOWA method 
      seemed to be the result of an excessive amount of drug (30 micrograms) in the 
      disks, a light inoculum, and a high susceptible breakpoint (less than or equal to 
      25-50 micrograms/ml). Until these and other major technical differences between 
      these two methods are resolved by internationally accepted testing standards, 
      susceptibility statistics, and/or clinical trials, information from the United 
      States and Japan cannot be reliably compared.
FAU - Jones, R N
AU  - Jones RN
AD  - Clinical Microbiology Institute, Inc., Tualatin, Oregon.
FAU - Barry, A L
AU  - Barry AL
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - United States
TA  - Diagn Microbiol Infect Dis
JT  - Diagnostic microbiology and infectious disease
JID - 8305899
RN  - Q91FH1328A (Methicillin)
RN  - UH95VD7V76 (Oxacillin)
SB  - IM
MH  - Methicillin/pharmacology
MH  - *Microbial Sensitivity Tests
MH  - Oxacillin/pharmacology
MH  - *Penicillin Resistance
MH  - Staphylococcus/*drug effects
EDAT- 1989/09/01 00:00
MHDA- 1989/09/01 00:01
CRDT- 1989/09/01 00:00
PHST- 1989/09/01 00:00 [pubmed]
PHST- 1989/09/01 00:01 [medline]
PHST- 1989/09/01 00:00 [entrez]
AID - 0732-8893(89)90107-7 [pii]
AID - 10.1016/0732-8893(89)90107-7 [doi]
PST - ppublish
SO  - Diagn Microbiol Infect Dis. 1989 Sep-Oct;12(5):381-4. doi: 
      10.1016/0732-8893(89)90107-7.