PMID- 26130248
OWN - NLM
STAT- MEDLINE
DCOM- 20160801
LR  - 20181113
IS  - 1432-198X (Electronic)
IS  - 0931-041X (Linking)
VI  - 30
IP  - 9
DP  - 2015 Sep
TI  - Whether or not to accept a deceased donor kidney offer for a pediatric patient.
PG  - 1529-36
LID - 10.1007/s00467-015-3139-x [doi]
AB  - The expansion of the number of children on the deceased donor renal transplant 
      waitlist has far outstripped the supply of organs in most countries, leading to 
      numerous adjustments to increase supply and to maximize the utility of donor 
      organs. The system for organ allocation varies by country based on local laws, 
      priorities, and resources. Adjustments are made to optimize allocation, enhance 
      post-transplant survival benefit, decrease unequal transplant access, and 
      optimize utilization of donated kidneys. Allocation of deceased donor kidneys is 
      based on several criteria; however, the final decision to accept or reject the 
      offered kidney is made by the potential recipient's transplant team 
      (surgeon/nephrologist). Several considerations including assessment of the donor 
      quality, the human leukocyte antigen (HLA) match between the donor and the 
      recipient, numerous recipient factors, the geographical location of the 
      recipient, and the organ all affect the decision to accept the organ or not for a 
      particular recipient. This decision must be made quickly, often on the spot. 
      Maximizing the benefit from this scarce resource raises difficult ethical issues. 
      The philosophies of equity and utility are often competing. In this manuscript, 
      we highlight a representative case that helps to focus on important issues for 
      the pediatric nephrologist to consider while making the decision to accept a 
      deceased donor kidney offer for a particular pediatric patient.
FAU - Chaudhuri, Abanti
AU  - Chaudhuri A
AD  - Department of Pediatric Nephrology, Stanford University Medical Center, 300 
      Pasteur Drive, Stanford, CA, 94305-5208, USA, abanti@stanford.edu.
FAU - James, Gerri
AU  - James G
FAU - Grimm, Paul
AU  - Grimm P
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20150701
PL  - Germany
TA  - Pediatr Nephrol
JT  - Pediatric nephrology (Berlin, Germany)
JID - 8708728
SB  - IM
MH  - Adolescent
MH  - Humans
MH  - Kidney Failure, Chronic/*surgery
MH  - *Kidney Transplantation/ethics/methods/standards
MH  - Male
MH  - *Patient Care Management/methods/organization & administration
MH  - Patient Care Team/organization & administration
MH  - *Patient Selection
MH  - Quality Improvement
MH  - Tissue Donors
MH  - *Tissue and Organ Harvesting/ethics/methods
MH  - *Tissue and Organ Procurement/ethics/methods/organization & administration
MH  - Waiting Lists
EDAT- 2015/07/02 06:00
MHDA- 2016/08/02 06:00
CRDT- 2015/07/02 06:00
PHST- 2015/04/24 00:00 [received]
PHST- 2015/05/27 00:00 [accepted]
PHST- 2015/05/22 00:00 [revised]
PHST- 2015/07/02 06:00 [entrez]
PHST- 2015/07/02 06:00 [pubmed]
PHST- 2016/08/02 06:00 [medline]
AID - 10.1007/s00467-015-3139-x [pii]
AID - 10.1007/s00467-015-3139-x [doi]
PST - ppublish
SO  - Pediatr Nephrol. 2015 Sep;30(9):1529-36. doi: 10.1007/s00467-015-3139-x. Epub 
      2015 Jul 1.