PMID- 26137656
OWN - NLM
STAT- MEDLINE
DCOM- 20150812
LR  - 20191210
IS  - 1565-1088 (Print)
VI  - 17
IP  - 5
DP  - 2015 May
TI  - High Degree Atrioventricular Block Complicating Acute Myocardial Infarction 
      Treated with Primary Percutaneous Coronary Intervention: Incidence, Predictors 
      and Outcomes.
PG  - 298-301
AB  - BACKGROUND: In the era of primary percutaneous coronary intervention (PPCI), 
      information on the incidence and prognostic significance of high degree 
      atrioventricular block (AVB) in ST elevation myocardial infarction (STEMI) 
      patients is limited. OBJECTIVES: To assess the incidence, time of onset, 
      predictors and prognostic significance of high degree AVB in a large cohort of 
      consecutive STEMI patients undergoing PPCI. METHODS: We retrospectively studied 
      1244 consecutive STEMI patients undergoing PPCI. Patient records were reviewed 
      for the presence of high degree AVB, its time of occurrence and relation to 
      in-hospital complications, as well as long-term mortality over a 5 year period. 
      RESULTS: High degree AVB was present in 33 patients (3.0%), in 25 (76%) of whom 
      the conduction disorder occurred prior to PPCI. Twelve patients (36%) required 
      temporary pacing, all prior to or during coronary intervention, and all AVB 
      resolved spontaneously before hospital discharge. AVB was associated with a 
      significantly higher 30 day (15% vs. 2.0%, P = 0.001) and long-term mortality 
      rate (30% vs. 6.0%, P < 0.001). Time of AVB had no effect on mortality. In a 
      multivariate regression model, AVB emerged as an independent predictor for 
      long-term mortality (hazard ratio 2.8, 95% confidence interval 1.20-6.44, P = 
      0.001). CONCLUSIONS: High degree AVB remains a significant prognostic marker in 
      STEMI patients in the PPCI era, albeit transient.
FAU - Shacham, Yacov
AU  - Shacham Y
FAU - Leshem-Rubinow, Eran
AU  - Leshem-Rubinow E
FAU - Steinvil, Arie
AU  - Steinvil A
FAU - Keren, Gad
AU  - Keren G
FAU - Roth, Arie
AU  - Roth A
FAU - Arbel, Yaron
AU  - Arbel Y
LA  - eng
PT  - Journal Article
PT  - Observational Study
PL  - Israel
TA  - Isr Med Assoc J
JT  - The Israel Medical Association journal : IMAJ
JID - 100930740
SB  - IM
MH  - Aged
MH  - *Atrioventricular Block/diagnosis/epidemiology/etiology
MH  - Comorbidity
MH  - Electrocardiography
MH  - Female
MH  - Hospital Mortality
MH  - Humans
MH  - Incidence
MH  - Israel/epidemiology
MH  - Male
MH  - Middle Aged
MH  - *Myocardial Infarction/complications/diagnosis/mortality/therapy
MH  - Outcome Assessment, Health Care
MH  - *Percutaneous Coronary Intervention/methods/statistics & numerical data
MH  - Prognosis
MH  - Retrospective Studies
MH  - Risk Factors
MH  - Time Factors
EDAT- 2015/07/04 06:00
MHDA- 2015/08/13 06:00
CRDT- 2015/07/04 06:00
PHST- 2015/07/04 06:00 [entrez]
PHST- 2015/07/04 06:00 [pubmed]
PHST- 2015/08/13 06:00 [medline]
PST - ppublish
SO  - Isr Med Assoc J. 2015 May;17(5):298-301.