PMID- 26142120 OWN - NLM STAT- MEDLINE DCOM- 20161103 LR - 20181113 IS - 1432-0703 (Electronic) IS - 0090-4341 (Print) IS - 0090-4341 (Linking) VI - 70 IP - 1 DP - 2016 Jan TI - Organohalogen Contaminants and Vitamins in Northern Fur Seals (Callorhinus ursinus) Collected During Subsistence Hunts in Alaska. PG - 96-105 LID - 10.1007/s00244-015-0179-y [doi] AB - During native subsistence hunts from 1987 to 2007, blubber and liver samples from 50 subadult male northern fur seals (Callorhinus ursinus) were collected on St. Paul Island, Alaska. Samples were analyzed for legacy persistent organic pollutants (POPs), recently phased-out/current-use POPs, and vitamins. The legacy POPs measured from blubber samples included polychlorinated biphenyl congeners, DDT (and its metabolites), chlorobenzenes, chlordanes, and mirex. Recently phased-out/current-use POPs included in the blubber analysis were the flame retardants, polybrominated diphenyl ethers, and hexabromocyclododecanes. The chemical surfactants, perfluorinated alkyl acids, and vitamins A and E were assessed in the liver samples. Overall, concentrations of legacy POPs are similar to levels seen in seal samples from other areas of the North Pacific Ocean and the Bering Sea. Statistically significant correlations were seen between compounds with similar functions (pesticides, flame retardants, vitamins). With sample collection spanning two decades, the temporal trends in the concentrations of POPs and vitamins were assessed. For these animals, the concentrations of the legacy POPs tend to decrease or stay the same with sampling year; however, the concentrations of the current-use POPs increased with sampling year. Vitamin concentrations tended to stay the same across the sampling years. With the population of northern fur seals from St. Paul Island on the decline, a detailed assessment of exposure to contaminants and the correlations with vitamins fills a critical gap for identifying potential population risk factors that might be associated with health effects. FAU - Reiner, Jessica L AU - Reiner JL AD - Chemical Sciences Division, Hollings Marine Laboratory, National Institute of Standards and Technology, Charleston, SC, 29412, USA. jessica.reiner@nist.gov. FAU - Becker, Paul R AU - Becker PR AD - Chemical Sciences Division, Hollings Marine Laboratory, National Institute of Standards and Technology, Charleston, SC, 29412, USA. FAU - Gribble, Matthew O AU - Gribble MO AD - Department of Preventive Medicine, University of Southern California, Los Angeles, CA, 90032, USA. FAU - Lynch, Jennifer M AU - Lynch JM AD - Chemical Sciences Division, Hollings Marine Laboratory, National Institute of Standards and Technology, Charleston, SC, 29412, USA. FAU - Moors, Amanda J AU - Moors AJ AD - Chemical Sciences Division, Hollings Marine Laboratory, National Institute of Standards and Technology, Charleston, SC, 29412, USA. FAU - Ness, Jennifer AU - Ness J AD - Chemical Sciences Division, Hollings Marine Laboratory, National Institute of Standards and Technology, Charleston, SC, 29412, USA. FAU - Peterson, Danielle AU - Peterson D AD - Chemical Sciences Division, Hollings Marine Laboratory, National Institute of Standards and Technology, Charleston, SC, 29412, USA. FAU - Pugh, Rebecca S AU - Pugh RS AD - Chemical Sciences Division, Hollings Marine Laboratory, National Institute of Standards and Technology, Charleston, SC, 29412, USA. FAU - Ragland, Tamika AU - Ragland T AD - Department of Chemistry, Purdue University, West Lafayette, IN, 47907, USA. FAU - Rimmer, Catherine AU - Rimmer C AD - Chemical Sciences Division, National Institute of Standards and Technology, Gaithersburg, MD, 20899, USA. FAU - Rhoderick, Jody AU - Rhoderick J AD - Chemical Sciences Division, Hollings Marine Laboratory, National Institute of Standards and Technology, Charleston, SC, 29412, USA. FAU - Schantz, Michele M AU - Schantz MM AD - Chemical Sciences Division, National Institute of Standards and Technology, Gaithersburg, MD, 20899, USA. FAU - Trevillian, Jennifer AU - Trevillian J AD - Chemical Sciences Division, Hollings Marine Laboratory, National Institute of Standards and Technology, Charleston, SC, 29412, USA. FAU - Kucklick, John R AU - Kucklick JR AD - Chemical Sciences Division, Hollings Marine Laboratory, National Institute of Standards and Technology, Charleston, SC, 29412, USA. LA - eng GR - 9999-NIST/Intramural NIST DOC/United States GR - T32 ES013678/ES/NIEHS NIH HHS/United States GR - T32ES013678-07/ES/NIEHS NIH HHS/United States PT - Journal Article PT - Research Support, N.I.H., Extramural PT - Research Support, U.S. Gov't, Non-P.H.S. DEP - 20150704 PL - United States TA - Arch Environ Contam Toxicol JT - Archives of environmental contamination and toxicology JID - 0357245 RN - 0 (Halogenated Diphenyl Ethers) RN - 0 (Hydrocarbons, Halogenated) RN - 0 (Vitamins) RN - 0 (Water Pollutants, Chemical) RN - 11103-57-4 (Vitamin A) RN - DFC2HB4I0K (Polychlorinated Biphenyls) SB - IM MH - Adipose Tissue/metabolism MH - Alaska MH - Animals MH - Fur Seals/*metabolism MH - Halogenated Diphenyl Ethers/metabolism MH - Hydrocarbons, Halogenated/*metabolism MH - Polychlorinated Biphenyls/metabolism MH - Vitamin A MH - Vitamins/*metabolism MH - Water Pollutants, Chemical/*metabolism PMC - PMC4817544 MID - NIHMS771578 OID - NLM: NISTPA771578 [Available on 01/01/17] COIS- Compliance with Ethical Standards Conflict of Interest: The authors declare that they have no conflict of interest. EDAT- 2015/07/05 06:00 MHDA- 2016/11/04 06:00 PMCR- 2017/01/01 CRDT- 2015/07/05 06:00 PHST- 2015/02/28 00:00 [received] PHST- 2015/06/06 00:00 [accepted] PHST- 2015/07/05 06:00 [entrez] PHST- 2015/07/05 06:00 [pubmed] PHST- 2016/11/04 06:00 [medline] PHST- 2017/01/01 00:00 [pmc-release] AID - 10.1007/s00244-015-0179-y [pii] AID - 10.1007/s00244-015-0179-y [doi] PST - ppublish SO - Arch Environ Contam Toxicol. 2016 Jan;70(1):96-105. doi: 10.1007/s00244-015-0179-y. Epub 2015 Jul 4.