PMID- 26142849
OWN - NLM
STAT- MEDLINE
DCOM- 20160607
LR  - 20181202
IS  - 1525-3198 (Electronic)
IS  - 0022-0302 (Linking)
VI  - 98
IP  - 9
DP  - 2015 Sep
TI  - Effect of yogurt containing deep sea water on health-related serum parameters and 
      intestinal microbiota in mice.
PG  - 5967-73
LID - S0022-0302(15)00454-3 [pii]
LID - 10.3168/jds.2015-9492 [doi]
AB  - Deep sea water (DSW) has health benefits and is widely used as food supplement; 
      however, its effect in fermented products has not been explored. Here, we 
      investigated the effect of DSW-containing yogurt on health-related serum 
      parameters and intestinal microbiota in mice. Animals were assigned to 3 feeding 
      groups, which received water (control), normal yogurt (N-yogurt), or 
      DSW-containing yogurt (DSW-yogurt) with a basal diet. Mice were killed at wk 4 or 
      8 of feeding and analyzed for serum parameters and microbial population in the 
      small intestine. Both yogurt groups demonstrated increased populations of 
      intestinal lactic acid bacteria compared with the control group. The activity of 
      serum aspartate aminotransferase and alanine aminotransferase was markedly 
      decreased in the DSW-yogurt and N-yogurt groups, and triglyceride level tended to 
      be lower in the DSW-yogurt group compared with that in the control mice. 
      Furthermore, the DSW-yogurt group showed a more significant decrease in the ratio 
      of total cholesterol to high-density lipoprotein-cholesterol than did the 
      N-yogurt group. These findings suggest that DSW supplementation of yogurt can 
      increase its beneficial effects on lipid metabolism.
CI  - Copyright (c) 2015 American Dairy Science Association. Published by Elsevier Inc. 
      All rights reserved.
FAU - Kang, Sun Moon
AU  - Kang SM
AD  - Animal Products Utilization Division, National Institute of Animal Science, Rural 
      Development Administration, 1500 Kongjwipatjwi-ro, Iseo-myeon, Wanju-gun 565-851, 
      Korea.
FAU - Jhoo, Jin Woo
AU  - Jhoo JW
AD  - Division of Applied Animal Science, College of Animal Life Sciences, Kangwon 
      National University, KNU Ave 1, Chuncheon 200-701, Korea.
FAU - Pak, Jae In
AU  - Pak JI
AD  - Division of Applied Animal Science, College of Animal Life Sciences, Kangwon 
      National University, KNU Ave 1, Chuncheon 200-701, Korea.
FAU - Kwon, Ill Kyoung
AU  - Kwon IK
AD  - Division of Applied Animal Science, College of Animal Life Sciences, Kangwon 
      National University, KNU Ave 1, Chuncheon 200-701, Korea.
FAU - Lee, Sung Ki
AU  - Lee SK
AD  - Division of Applied Animal Science, College of Animal Life Sciences, Kangwon 
      National University, KNU Ave 1, Chuncheon 200-701, Korea.
FAU - Kim, Gur Yoo
AU  - Kim GY
AD  - Division of Applied Animal Science, College of Animal Life Sciences, Kangwon 
      National University, KNU Ave 1, Chuncheon 200-701, Korea. Electronic address: 
      gykim@kangwon.ac.kr.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20150702
PL  - United States
TA  - J Dairy Sci
JT  - Journal of dairy science
JID - 2985126R
RN  - 0 (Cholesterol, HDL)
RN  - 0 (Cholesterol, LDL)
RN  - 0 (Triglycerides)
RN  - EC 2.6.1.1 (Aspartate Aminotransferases)
RN  - EC 2.6.1.2 (Alanine Transaminase)
SB  - IM
MH  - Alanine Transaminase/blood
MH  - Animals
MH  - Aspartate Aminotransferases/blood
MH  - Cholesterol, HDL/blood
MH  - Cholesterol, LDL/blood
MH  - *Gastrointestinal Microbiome
MH  - Intestines/*microbiology
MH  - Lactobacillus/growth & development
MH  - Mice
MH  - Pediococcus/growth & development
MH  - Seawater/*analysis
MH  - Triglycerides/blood
MH  - Yogurt/*analysis/microbiology
OTO - NOTNLM
OT  - deep sea water
OT  - intestinal microbiota
OT  - serum parameter
OT  - yogurt
EDAT- 2015/07/06 06:00
MHDA- 2016/06/09 06:00
CRDT- 2015/07/06 06:00
PHST- 2015/02/21 00:00 [received]
PHST- 2015/05/26 00:00 [accepted]
PHST- 2015/07/06 06:00 [entrez]
PHST- 2015/07/06 06:00 [pubmed]
PHST- 2016/06/09 06:00 [medline]
AID - S0022-0302(15)00454-3 [pii]
AID - 10.3168/jds.2015-9492 [doi]
PST - ppublish
SO  - J Dairy Sci. 2015 Sep;98(9):5967-73. doi: 10.3168/jds.2015-9492. Epub 2015 Jul 2.