PMID- 26143169
OWN - NLM
STAT- MEDLINE
DCOM- 20160325
LR  - 20181202
IS  - 1090-2414 (Electronic)
IS  - 0147-6513 (Linking)
VI  - 120
DP  - 2015 Oct
TI  - Determination of perfluorinated sulfonate and perfluorinated acids in tissues of 
      free-living European beaver (castor fiber L.) by d-SPE/ micro-UHPLC-MS/MS.
PG  - 436-44
LID - S0147-6513(15)00314-0 [pii]
LID - 10.1016/j.ecoenv.2015.06.029 [doi]
AB  - Perfluorooctanesulfonate (PFOS) and perfluorooctanoic acid (PFOA) are the main 
      representatives of an rising class of persistent organic pollutants (POPs), 
      perfluorochemicals (PFCs). In this study, determination of selected PFCs 
      concentration in liver, brain, tail, adipose and peritoneum tissues of 
      free-living European beaver (Castor fiber L.) was addressed. Tissue samples, 
      collected from beavers living in Masurian Lakeland (NE Poland), were analyzed by 
      dispersive Solid Phase Extraction (d-SPE) with micro-UHPLC-MS/MS system. In a 
      group of ten selected pefrluorinated compounds only two perfluorinated acids 
      (PFOA and PFNA) and one perfluorinated sulfonate (PFOS) were quantified. PFOA was 
      detected in all analysed tissue samples in both female and male beavers in a 
      range from 0.55 to 0.98ngg(-1) ww whereas PFOS was identified in all analyzed 
      female beaver tissues and only in liver, subcutaneous adipose and peritoneum 
      tissues of male beavers at the concentration level from 0.86 to 5.08ngg(-1) ww. 
      PFNA was only identified in female beaver tissues (liver, subcutaneous adipose 
      and peritoneum) in a range from 1.50 to 6.61ngg(-1) ww. This study demonstrated 
      the bioaccumulation of PFCs in tissue samples collected from beavers living in 
      area known as green lungs of Poland. The results provided in this study indicate 
      for the increasing risk of PFCs occurrence in the environment and the level of 
      PFCs in tissue of free-living European beavers may serve as bioindicator of 
      environmental pollution by these compounds.
CI  - Copyright (c) 2015 Elsevier Inc. All rights reserved.
FAU - Surma, Magdalena
AU  - Surma M
AD  - Malopolska Centre of Food Monitoring, Faculty of Food Technology, University of 
      Agriculture in Krakow, Balicka St.122, 30-149 Krakow, Poland. Electronic address: 
      m.surma@ur.krakow.pl.
FAU - Gizejewski, Zygmunt
AU  - Gizejewski Z
AD  - Department of Gamete and Embryo Biology, Institute of Animal Reproduction and 
      Food Research of the Polish Academy of Sciences, Division of Reproductive 
      Biology, Bydgoska St. 7, 10-243 Olsztyn, Poland.
FAU - Zielinski, Henryk
AU  - Zielinski H
AD  - Department of Chemistry and Biodynamics of Food, Institute of Animal Reproduction 
      and Food Research of the Polish Academy of Sciences, Division of Food Science, 
      Tuwima St.10, 10-748 Olsztyn, Poland.
LA  - eng
PT  - Journal Article
DEP - 20150702
PL  - Netherlands
TA  - Ecotoxicol Environ Saf
JT  - Ecotoxicology and environmental safety
JID - 7805381
RN  - 0 (Alkanesulfonic Acids)
RN  - 0 (Caprylates)
RN  - 0 (Fluorocarbons)
RN  - 0 (Hydrocarbons, Fluorinated)
RN  - 947VD76D3L (perfluorooctanoic acid)
RN  - 9H2MAI21CL (perfluorooctane sulfonic acid)
SB  - IM
MH  - Alkanesulfonic Acids/analysis/*toxicity
MH  - Animals
MH  - Blood-Brain Barrier/drug effects/metabolism
MH  - Caprylates/analysis/*toxicity
MH  - Chromatography, High Pressure Liquid/methods
MH  - Environmental Monitoring/*methods
MH  - Female
MH  - Fluorocarbons/analysis/*toxicity
MH  - Hydrocarbons, Fluorinated/analysis/toxicity
MH  - Limit of Detection
MH  - Male
MH  - Poland
MH  - Rodentia/*metabolism
MH  - Solid Phase Extraction/*methods
MH  - Tandem Mass Spectrometry/*methods
OTO - NOTNLM
OT  - Beaver
OT  - PFCs
OT  - PFOA
OT  - PFOS
OT  - d-SPE
OT  - micro-UHPLC-MS/MS
EDAT- 2015/07/06 06:00
MHDA- 2016/03/26 06:00
CRDT- 2015/07/06 06:00
PHST- 2015/03/06 00:00 [received]
PHST- 2015/06/13 00:00 [revised]
PHST- 2015/06/22 00:00 [accepted]
PHST- 2015/07/06 06:00 [entrez]
PHST- 2015/07/06 06:00 [pubmed]
PHST- 2016/03/26 06:00 [medline]
AID - S0147-6513(15)00314-0 [pii]
AID - 10.1016/j.ecoenv.2015.06.029 [doi]
PST - ppublish
SO  - Ecotoxicol Environ Saf. 2015 Oct;120:436-44. doi: 10.1016/j.ecoenv.2015.06.029. 
      Epub 2015 Jul 2.