PMID- 26152455
OWN - NLM
STAT- MEDLINE
DCOM- 20160401
LR  - 20240516
IS  - 1746-1596 (Electronic)
IS  - 1746-1596 (Linking)
VI  - 10
DP  - 2015 Jul 8
TI  - A case report of undiagnosed postpartum hemolytic uremic syndrome.
PG  - 89
LID - 10.1186/s13000-015-0278-0 [doi]
LID - 89
AB  - BACKGROUND: Postpartum hemolytic uremic syndrome (PHUS) is a severe thrombotic 
      microangiopathy (TMA) that is clinically characterized by hemolytic anemia, renal 
      dysfunction, and low platelet levels after childbirth. Here, we report a rare 
      case of unexpected death due to PHUS. CASE PRESENTATION: A 23-year-old parturient 
      had an uncomplicated cesarean section at 40 weeks gestation. The immediate 
      postpartum course was uneventful. However, eight days post delivery, the patient 
      developed severe nausea and vomiting followed by hematuria, spontaneous bruising, 
      marked pallor, icteric sclera, and lethargy. Laboratory findings revealed that 
      the patient had hemolytic anemia, thrombocytopenia, and acute renal failure. This 
      patient died approximately 29 h after the onset of symptoms. Post-mortem 
      examination confirmed that the patient had PHUS. CONCLUSIONS: This paper 
      addresses the need for a renal histological examination in addition to a thorough 
      clinical history and appropriate laboratory tests for the rapid and accurate 
      diagnosis of PHUS. Early detection and diagnosis can significantly improve the 
      prognosis and optimize maternal outcomes.
FAU - Mu, Jiao
AU  - Mu J
AD  - Department of Forensic Medicine, Tongji Medical College of Huazhong University of 
      Science and Technology, No. 13 Hangkong Road, Wuhan, Hubei, 430030, PR China. 
      123730562@qq.com.
AD  - Department of Phatology, Hebei North University, No. 11 Zuanshinan Road, 
      Zhangjiakou, Hebei, 075000, PR China. 123730562@qq.com.
FAU - Zhang, Ji
AU  - Zhang J
AD  - Department of Forensic Medicine, Tongji Medical College of Huazhong University of 
      Science and Technology, No. 13 Hangkong Road, Wuhan, Hubei, 430030, PR China. 
      510602974@qq.com.
FAU - Sunnassee, Ananda
AU  - Sunnassee A
AD  - Ministry of Health and Quality of Life, Victoria Hospital, Quatre Bornes, 
      Mauritius. 378579104@qq.com.
FAU - Dong, Hongmei
AU  - Dong H
AD  - Department of Forensic Medicine, Tongji Medical College of Huazhong University of 
      Science and Technology, No. 13 Hangkong Road, Wuhan, Hubei, 430030, PR China. 
      hongmeidong1@hotmail.com.
LA  - eng
PT  - Case Reports
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20150708
PL  - England
TA  - Diagn Pathol
JT  - Diagnostic pathology
JID - 101251558
SB  - IM
MH  - Fatal Outcome
MH  - Female
MH  - *Hemolytic-Uremic Syndrome
MH  - Humans
MH  - *Postpartum Period
MH  - Young Adult
PMC - PMC4495808
EDAT- 2015/07/15 06:00
MHDA- 2016/04/02 06:00
PMCR- 2015/07/08
CRDT- 2015/07/09 06:00
PHST- 2015/02/06 00:00 [received]
PHST- 2015/04/16 00:00 [accepted]
PHST- 2015/07/09 06:00 [entrez]
PHST- 2015/07/15 06:00 [pubmed]
PHST- 2016/04/02 06:00 [medline]
PHST- 2015/07/08 00:00 [pmc-release]
AID - 10.1186/s13000-015-0278-0 [pii]
AID - 278 [pii]
AID - 10.1186/s13000-015-0278-0 [doi]
PST - epublish
SO  - Diagn Pathol. 2015 Jul 8;10:89. doi: 10.1186/s13000-015-0278-0.