PMID- 26154873
OWN - NLM
STAT- MEDLINE
DCOM- 20160620
LR  - 20150825
IS  - 1931-8405 (Electronic)
IS  - 0889-2229 (Linking)
VI  - 31
IP  - 9
DP  - 2015 Sep
TI  - Short communication: mucocutaneous leishmaniasis in HIV-related immune 
      reconstitution syndrome.
PG  - 889-92
LID - 10.1089/aid.2015.0075 [doi]
AB  - Immune reconstitution inflammatory syndrome (IRIS) is an immuno-pathologic 
      reaction to quiescent opportunistic microbial pathogens upon restoration of 
      underlying immune defects. Here we report a Honduran patient with HIV/AIDS who 
      developed a facial rash worsening on antiretroviral therapy and increasing CD4 
      count. Culture and PCR analysis from the skin biopsy identified Leishmania 
      panamensis, which was effectively treated with long-term liposomal amphotericin 
      B. This is the first report of mucocutaneous leishmaniasis (MCL)-associated IRIS 
      due to L. panamensis.
FAU - Lee, Grace L
AU  - Lee GL
AD  - 1 Division of Dermatology, Wexner Medical Center, The Ohio State University , 
      Columbus, Ohio.
FAU - Woods, Kenneth L
AU  - Woods KL
AD  - 2 Division of Infectious Diseases, Department of Internal Medicine, Wexner 
      Medical Center, The Ohio State University , Columbus, Ohio.
FAU - Clark, Lindsey
AU  - Clark L
AD  - 3 Division of Dermatopathology, Department of Pathology, Wexner Medical Center, 
      The Ohio State University , Columbus, Ohio.
FAU - Peters, Sara
AU  - Peters S
AD  - 3 Division of Dermatopathology, Department of Pathology, Wexner Medical Center, 
      The Ohio State University , Columbus, Ohio.
FAU - Wong, Henry K
AU  - Wong HK
AD  - 1 Division of Dermatology, Wexner Medical Center, The Ohio State University , 
      Columbus, Ohio.
FAU - McGwire, Bradford S
AU  - McGwire BS
AD  - 2 Division of Infectious Diseases, Department of Internal Medicine, Wexner 
      Medical Center, The Ohio State University , Columbus, Ohio.
LA  - eng
PT  - Case Reports
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20150708
PL  - United States
TA  - AIDS Res Hum Retroviruses
JT  - AIDS research and human retroviruses
JID - 8709376
RN  - 0 (Antiprotozoal Agents)
RN  - 7XU7A7DROE (Amphotericin B)
SB  - IM
MH  - *AIDS-Related Opportunistic Infections/drug therapy/immunology
MH  - Adult
MH  - Amphotericin B/administration & dosage/therapeutic use
MH  - Antiprotozoal Agents/administration & dosage/therapeutic use
MH  - Female
MH  - HIV Infections/*complications/immunology
MH  - Humans
MH  - Immune Reconstitution Inflammatory Syndrome/*complications/immunology
MH  - *Leishmania
MH  - Leishmaniasis, Mucocutaneous/drug therapy/*etiology/immunology
MH  - Polymerase Chain Reaction
EDAT- 2015/07/15 06:00
MHDA- 2016/06/21 06:00
CRDT- 2015/07/09 06:00
PHST- 2015/07/09 06:00 [entrez]
PHST- 2015/07/15 06:00 [pubmed]
PHST- 2016/06/21 06:00 [medline]
AID - 10.1089/aid.2015.0075 [doi]
PST - ppublish
SO  - AIDS Res Hum Retroviruses. 2015 Sep;31(9):889-92. doi: 10.1089/aid.2015.0075. 
      Epub 2015 Jul 8.