PMID- 26155404
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20210211
LR  - 20210211
IS  - 2162-4011 (Print)
IS  - 2162-402X (Electronic)
IS  - 2162-4011 (Linking)
VI  - 4
IP  - 5
DP  - 2015 May
TI  - HLA class I as a predictor of clinical prognosis and CTL infiltration as a 
      predictor of chemosensitivity in ovarian cancer.
PG  - e1005507
LID - e1005507
AB  - Cytotoxic T lymphocytes (CTLs) recognize the human leukocyte antigen (HLA) class 
      I and antigenic peptide complex, and they play a crucial role in cancer immunity. 
      Our recent study revealed that HLA class I downregulation is related to poorer 
      prognosis and a low level of intratumoral CTLs is associated with platinum 
      resistance, indicating the significance of immunological surveillance.
FAU - Hirohashi, Yoshihiko
AU  - Hirohashi Y
AD  - Department of Pathology; Sapporo Medical University School of Medicine ; Sapporo, 
      Japan.
FAU - Torigoe, Toshihiko
AU  - Torigoe T
AD  - Department of Pathology; Sapporo Medical University School of Medicine ; Sapporo, 
      Japan.
FAU - Mariya, Tasuku
AU  - Mariya T
AD  - Department of Pathology; Sapporo Medical University School of Medicine ; Sapporo, 
      Japan ; Department of Obstetrics and Gynecology; Sapporo Medical University 
      School of Medicine ; Sapporo, Japan.
FAU - Kochin, Vitaly
AU  - Kochin V
AD  - Department of Pathology; Sapporo Medical University School of Medicine ; Sapporo, 
      Japan.
FAU - Saito, Tsuyoshi
AU  - Saito T
AD  - Department of Obstetrics and Gynecology; Sapporo Medical University School of 
      Medicine ; Sapporo, Japan.
FAU - Sato, Noriyuki
AU  - Sato N
AD  - Department of Pathology; Sapporo Medical University School of Medicine ; Sapporo, 
      Japan.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20150323
PL  - United States
TA  - Oncoimmunology
JT  - Oncoimmunology
JID - 101570526
PMC - PMC4485746
OTO - NOTNLM
OT  - CTL
OT  - CTL, cytotoxic T lymphocyte
OT  - HLA class I
OT  - HLA, human leukocyte antigen
OT  - MHC, major histocompatibility complex
OT  - TAA, tumor-associated antigen
OT  - ovarian cancer
OT  - platinum resistance
EDAT- 2015/07/15 06:00
MHDA- 2015/07/15 06:01
PMCR- 2016/03/23
CRDT- 2015/07/09 06:00
PHST- 2014/12/28 00:00 [received]
PHST- 2014/12/30 00:00 [accepted]
PHST- 2015/07/09 06:00 [entrez]
PHST- 2015/07/15 06:00 [pubmed]
PHST- 2015/07/15 06:01 [medline]
PHST- 2016/03/23 00:00 [pmc-release]
AID - 1005507 [pii]
AID - 10.1080/2162402X.2015.1005507 [doi]
PST - epublish
SO  - Oncoimmunology. 2015 Mar 23;4(5):e1005507. doi: 10.1080/2162402X.2015.1005507. 
      eCollection 2015 May.