PMID- 26155405 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20210112 IS - 2162-4011 (Print) IS - 2162-402X (Electronic) IS - 2162-4011 (Linking) VI - 4 IP - 5 DP - 2015 May TI - B cells drive Th2 responses by instructing human dendritic cell maturation. PG - e1005508 LID - e1005508 AB - Dendritic cells (DCs) are known to regulate the functions of various immune cells. Reciprocal signaling by these immune cells also "educate" the DCs and determine the quality of the ensuing immune responses. Recently, we demonstrated that human DCs undergo maturation upon interaction with activated B cells to acquire unique abilities to promote polarization of Th2 cells. FAU - Maddur, Mohan S AU - Maddur MS AD - Institut National de la Sante et de la Recherche Medicale ; Paris, France ; Centre de Recherche des Cordeliers; Equipe - Immunopathology and Therapeutic Immunointervention ; Paris, France ; Sorbonne Universites, UPMC Univ Paris , Paris, France ; Emory Vaccine Center; Yerkes National Primate Research Center; Emory University ; Atlanta, GA, USA. FAU - Bayry, Jagadeesh AU - Bayry J AD - Institut National de la Sante et de la Recherche Medicale ; Paris, France ; Centre de Recherche des Cordeliers; Equipe - Immunopathology and Therapeutic Immunointervention ; Paris, France ; Sorbonne Universites, UPMC Univ Paris , Paris, France ; Universite Paris Descartes ; Sorbonne Paris Cite ; Paris, France ; International Associated Laboratory IMPACT (Institut National de la Sante et de la Recherche Medicale, France - Indian Council of Medical Research, India); National Institute of Immunohematology ; Mumbai, India. LA - eng PT - Journal Article DEP - 20150203 PL - United States TA - Oncoimmunology JT - Oncoimmunology JID - 101570526 PMC - PMC4485718 OTO - NOTNLM OT - B lymphocytes OT - BAFF-R, B-cell-activating factor receptor OT - BCR, B-cell receptor OT - DAMPs, damage-associated molecular patterns OT - DCs, dendritic cells OT - OX-40 ligand OT - OX-40L, OX-40 ligand OT - PAMPs, pathogen-derived molecular patterns (PAMPs) OT - TACI, transmembrane activator and calcium-modulating cyclophilin ligand interactor OT - Th2 OT - Tregs, regulatory T cells OT - antibody response OT - antitumor OT - dendritic cells EDAT- 2015/07/15 06:00 MHDA- 2015/07/15 06:01 PMCR- 2016/02/03 CRDT- 2015/07/09 06:00 PHST- 2014/12/30 00:00 [received] PHST- 2014/12/30 00:00 [accepted] PHST- 2015/07/09 06:00 [entrez] PHST- 2015/07/15 06:00 [pubmed] PHST- 2015/07/15 06:01 [medline] PHST- 2016/02/03 00:00 [pmc-release] AID - 1005508 [pii] AID - 10.1080/2162402X.2015.1005508 [doi] PST - epublish SO - Oncoimmunology. 2015 Feb 3;4(5):e1005508. doi: 10.1080/2162402X.2015.1005508. eCollection 2015 May.