PMID- 26157594 OWN - NLM STAT- PubMed-not-MEDLINE DCOM- 20150709 LR - 20200930 IS - 2093-2340 (Print) IS - 2092-6448 (Electronic) IS - 1598-8112 (Linking) VI - 47 IP - 2 DP - 2015 Jun TI - Fever of Unknown Origin: An Unusual Presentation of Anti-N-Methyl-D-Aspartate Receptor Encephalitis. PG - 129-32 LID - 10.3947/ic.2015.47.2.129 [doi] AB - Encephalitis associated with antibodies to the N-methyl-D-aspartate receptor (NMDAR) has variable clinical manifestations. Patients are often diagnosed with infectious processes because of prodromal symptoms and autonomic manifestations. Approximately 70% of patients have prodromal symptoms consisting of headache, fever, nausea, vomiting, and diarrhea, along with frequent autonomic manifestations, including tachycardia, and fluctuating blood pressure. A 36-year-old woman presented with uncontrolled fever and skin and soft tissue infections. She had shown psychiatric symptoms and abnormal behavior, and had been diagnosed with bipolar disorder. Antibodies to NMDAR were positive in cerebrospinal fluid (CSF) and serum samples, and pelvic computed tomography detected a large ovarian teratoma. The patient improved dramatically after removal of the teratoma and administration of corticosteroid therapy. When confronted with a young woman with uncontrolled fever and acute psychiatric symptoms, physicians should suspect anti-NMDAR encephalitis. FAU - Hur, Jian AU - Hur J AD - Department of Internal Medicine, Yeungnam University Medical Center, Daegu, Korea. LA - eng PT - Journal Article DEP - 20150630 PL - Korea (South) TA - Infect Chemother JT - Infection & chemotherapy JID - 101531537 PMC - PMC4495274 OTO - NOTNLM OT - Anti-N-methyl-D-aspartate receptor encephalitis OT - Dermoid cyst OT - Fever of unknown origin EDAT- 2015/07/15 06:00 MHDA- 2015/07/15 06:01 PMCR- 2015/06/01 CRDT- 2015/07/10 06:00 PHST- 2015/04/27 00:00 [received] PHST- 2015/05/30 00:00 [revised] PHST- 2015/05/31 00:00 [accepted] PHST- 2015/07/10 06:00 [entrez] PHST- 2015/07/15 06:00 [pubmed] PHST- 2015/07/15 06:01 [medline] PHST- 2015/06/01 00:00 [pmc-release] AID - 10.3947/ic.2015.47.2.129 [doi] PST - ppublish SO - Infect Chemother. 2015 Jun;47(2):129-32. doi: 10.3947/ic.2015.47.2.129. Epub 2015 Jun 30.