PMID- 26160873 OWN - NLM STAT- MEDLINE DCOM- 20160819 LR - 20220408 IS - 1399-3003 (Electronic) IS - 0903-1936 (Linking) VI - 46 IP - 4 DP - 2015 Oct TI - An official European Respiratory Society/American Thoracic Society research statement: interstitial pneumonia with autoimmune features. PG - 976-87 LID - 10.1183/13993003.00150-2015 [doi] AB - Many patients with an idiopathic interstitial pneumonia (IIP) have clinical features that suggest an underlying autoimmune process but do not meet established criteria for a connective tissue disease (CTD). Researchers have proposed differing criteria and terms to describe these patients, and lack of consensus over nomenclature and classification limits the ability to conduct prospective studies of a uniform cohort.The "European Respiratory Society/American Thoracic Society Task Force on Undifferentiated Forms of Connective Tissue Disease-associated Interstitial Lung Disease" was formed to create consensus regarding the nomenclature and classification criteria for patients with IIP and features of autoimmunity.The task force proposes the term "interstitial pneumonia with autoimmune features" (IPAF) and offers classification criteria organised around the presence of a combination of features from three domains: a clinical domain consisting of specific extra-thoracic features, a serologic domain consisting of specific autoantibodies, and a morphologic domain consisting of specific chest imaging, histopathologic or pulmonary physiologic features.A designation of IPAF should be used to identify individuals with IIP and features suggestive of, but not definitive for, a CTD. With IPAF, a sound platform has been provided from which to launch the requisite future research investigations of a more uniform cohort. CI - Copyright (c)ERS 2015. FAU - Fischer, Aryeh AU - Fischer A AD - Dept of Medicine, University of Colorado School of Medicine, Denver, CO, USA Task force chair Members of the writing group of the task force aryeh.fischer@ucdenver.edu. FAU - Antoniou, Katerina M AU - Antoniou KM AD - Thoracic Medicine, University of Crete, Heraklion, Greece. FAU - Brown, Kevin K AU - Brown KK AD - Dept of Medicine, National Jewish Health, Denver, CO, USA. FAU - Cadranel, Jacques AU - Cadranel J AD - Pneumologie, Hopital Tenon, Paris, France. FAU - Corte, Tamera J AU - Corte TJ AD - The Aldred Hospital, Melbourne, Australia Members of the writing group of the task force. FAU - du Bois, Roland M AU - du Bois RM AD - Interstitial Lung Disease Unit, Dept of Occupational Medicine, Royal Brompton Hospital, London, UK. FAU - Lee, Joyce S AU - Lee JS AD - Medicine, University of California San Francisco, San Francisco, CA, USA Members of the writing group of the task force. FAU - Leslie, Kevin O AU - Leslie KO AD - Pathology, Mayo Clinic, Scottsdale, AZ, USA. FAU - Lynch, David A AU - Lynch DA AD - Dept of Radiology, National Jewish Health, Denver, CO, USA. FAU - Matteson, Eric L AU - Matteson EL AD - Division of Rheumatology, Mayo College of Medicine, Rochester, MN, USA. FAU - Mosca, Marta AU - Mosca M AD - University of Pisa, Pisa, Italy. FAU - Noth, Imre AU - Noth I AD - Medicine, University of Chicago, Chicago, IL, USA. FAU - Richeldi, Luca AU - Richeldi L AD - Southampton General Hospital, Southampton, UK. FAU - Strek, Mary E AU - Strek ME AD - Medicine, University of Chicago, Chicago, IL, USA Members of the writing group of the task force. FAU - Swigris, Jeffrey J AU - Swigris JJ AD - Dept of Medicine, National Jewish Health, Denver, CO, USA Members of the writing group of the task force. FAU - Wells, Athol U AU - Wells AU AD - Interstitial Lung Disease Unit, Royal Brompton Hospital, London, UK. FAU - West, Sterling G AU - West SG AD - University of Colorado School of Medicine, Aurora, CO, USA. FAU - Collard, Harold R AU - Collard HR AD - Medicine, University of California San Francisco, San Francisco, CA, USA Members of the writing group of the task force Task force vice-chairs, and contributed equally to this manuscript. FAU - Cottin, Vincent AU - Cottin V AD - Service de Pneumologie, Hopital L. Pradel, Lyon, France Members of the writing group of the task force Task force vice-chairs, and contributed equally to this manuscript. CN - "ERS/ATS Task Force on Undifferentiated Forms of CTD-ILD" LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20150709 PL - England TA - Eur Respir J JT - The European respiratory journal JID - 8803460 RN - 0 (Autoantibodies) SB - IM CIN - Eur Respir J. 2016 Apr;47(4):1293-5. PMID: 27037322 CIN - Eur Respir J. 2016 Apr;47(4):1295-6. PMID: 27037323 MH - Autoantibodies/chemistry MH - Autoimmune Diseases/*diagnosis/therapy MH - Autoimmunity MH - Connective Tissue Diseases/immunology MH - Europe MH - Humans MH - Idiopathic Interstitial Pneumonias/*diagnosis/immunology/*therapy MH - Lung Diseases, Interstitial/*diagnosis/immunology/*therapy MH - Prospective Studies MH - Pulmonary Medicine/*standards MH - Societies, Medical MH - United States EDAT- 2015/07/15 06:00 MHDA- 2016/08/20 06:00 CRDT- 2015/07/11 06:00 PHST- 2015/01/27 00:00 [received] PHST- 2015/05/11 00:00 [accepted] PHST- 2015/07/11 06:00 [entrez] PHST- 2015/07/15 06:00 [pubmed] PHST- 2016/08/20 06:00 [medline] AID - 13993003.00150-2015 [pii] AID - 10.1183/13993003.00150-2015 [doi] PST - ppublish SO - Eur Respir J. 2015 Oct;46(4):976-87. doi: 10.1183/13993003.00150-2015. Epub 2015 Jul 9.