PMID- 26161055
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20150710
LR  - 20240323
IS  - 1642-395X (Print)
IS  - 2299-0046 (Electronic)
IS  - 1642-395X (Linking)
VI  - 32
IP  - 3
DP  - 2015 Jun
TI  - Topical steroid therapy in atopic dermatitis in theory and practice.
PG  - 162-6
LID - 10.5114/pdia.2014.40962 [doi]
AB  - INTRODUCTION: Topical glucocorticosteroids (GCSs) are commonly used in treatment 
      of atopic dermatitis (AD). AIM: To assess the patients' compliance with the 
      recommended instructions of the therapy. MATERIAL AND METHODS: The study involved 
      141 adult AD patients. The clinical course of AD and its treatment with GCSs 
      during the last year were analysed. RESULTS: In the periods of exacerbation the 
      lesions involved 10-50% of the skin surface area. Outpatient treatment in 
      specialised dermatological and/or allergology clinics was given to 93% of the 
      study subjects. Sixty-five out of 141 patients regularly attended medical control 
      examinations. Glucocorticosteroids, mostly very potent ones (70.2%), were applied 
      to all the subjects. 66.7% of patients obtained no information about their 
      medications' anti-inflammatory potential. The substances were applied more 
      frequently than twice daily by 36.4% of the patients. Seventy-two of 141 subjects 
      applied GCSs both temporarily and in the long-term treatment, for 8.3 weeks on 
      average. In the long-term treatment, in which very potent GCSs predominated 
      (70.7%), no one used intermittent therapy. One hundred and thirty patients 
      introduced their own modifications to the instructions concerning GCSs use, among 
      which 37.7% changed the site of application, 58.5% prolonged the duration of 
      application and 49.5% shortened it or occasionally temporarily withdrew the 
      prescribed drug. None of the patients knew the fingertip unit method of dose 
      assessment. Apart from steroid therapy, 56.7% of the patients carried out regular 
      care treatment. CONCLUSIONS: The AD patients need to be thoroughly educated by 
      the medical staff in the topical GCSs therapy in atopic dermatitis.
FAU - Jeziorkowska, Renata
AU  - Jeziorkowska R
AD  - Department of Dermatology, Medical University of Warsaw, Warsaw, Poland. Head of 
      the Department: Prof. Lidia Rudnicka MD, PhD.
FAU - Sysa-Jedrzejowska, Anna
AU  - Sysa-Jedrzejowska A
AD  - Department of Dermatology, University of Social Sciences, Lodz, Poland. Head of 
      the Department: Prof. Franciszek Seneczko MD, PhD.
FAU - Samochocki, Zbigniew
AU  - Samochocki Z
AD  - Department of Dermatology, Medical University of Warsaw, Warsaw, Poland. Head of 
      the Department: Prof. Lidia Rudnicka MD, PhD.
LA  - eng
PT  - Journal Article
DEP - 20150610
PL  - Poland
TA  - Postepy Dermatol Alergol
JT  - Postepy dermatologii i alergologii
JID - 101168357
PMC - PMC4495104
OTO - NOTNLM
OT  - atopic dermatitis
OT  - glucocorticosteroids
OT  - topical treatment
EDAT- 2015/07/15 06:00
MHDA- 2015/07/15 06:01
PMCR- 2015/06/01
CRDT- 2015/07/11 06:00
PHST- 2013/12/23 00:00 [received]
PHST- 2013/12/28 00:00 [revised]
PHST- 2014/01/02 00:00 [accepted]
PHST- 2015/07/11 06:00 [entrez]
PHST- 2015/07/15 06:00 [pubmed]
PHST- 2015/07/15 06:01 [medline]
PHST- 2015/06/01 00:00 [pmc-release]
AID - 22368 [pii]
AID - 10.5114/pdia.2014.40962 [doi]
PST - ppublish
SO  - Postepy Dermatol Alergol. 2015 Jun;32(3):162-6. doi: 10.5114/pdia.2014.40962. 
      Epub 2015 Jun 10.