PMID- 26161059
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20150710
LR  - 20240323
IS  - 1642-395X (Print)
IS  - 2299-0046 (Electronic)
IS  - 1642-395X (Linking)
VI  - 32
IP  - 3
DP  - 2015 Jun
TI  - Evaluation of in utero sensitization by screening antigen-specific immunoglobulin 
      E levels in umbilical cord blood.
PG  - 184-8
LID - 10.5114/pdia.2015.48051 [doi]
AB  - INTRODUCTION: The incidence of asthma and atopic reactions is increasing 
      worldwide. Previous reports have suggested that maternal exposure to allergens 
      during pregnancy may have potential effects on allergic sensitization in infants. 
      AIM: To evaluate the effects of maternal exposure to environmental allergens 
      during pregnancy on in-utero sensitization. MATERIAL AND METHODS: Two hundred 
      mothers and their infants were analyzed in this cross-sectional study. Mothers 
      were given a questionnaire that had a series of questions to evaluate the 
      maternal allergic status and environmental exposures during pregnancy. Plasma 
      specific immunoglobulin E (IgE) levels to pets, grass, food (nuts) of all mothers 
      and their infants were analyzed by an immune-enzymatic assay. RESULTS: There was 
      no significant correlation between plasma specific IgE positivity in mothers, 
      with regard to keeping indoor domestic pets, living in grass habitat, eating nuts 
      in diet. A significant correlation was found between specific IgE presence in 
      mothers and allergic reactions; however, there was no correlation between plasma 
      specific IgE positivity of mothers and infants. CONCLUSIONS: We concluded that 
      prenatal maternal sensitivity to environmental allergens could not be evaluated 
      as a predictive factor for in-utero sensitization.
FAU - Gurbuz, Tamay
AU  - Gurbuz T
AD  - Department of Pediatrics, Haydarpasa Numune Training and Research Hospital, 
      Istanbul, Turkey. Head of the Department: Cagatay Nuhoglu MD, Assoc. Prof.
FAU - Karakol, Burcu
AU  - Karakol B
AD  - Department of Pediatrics, Haydarpasa Numune Training and Research Hospital, 
      Istanbul, Turkey. Head of the Department: Cagatay Nuhoglu MD, Assoc. Prof.
FAU - Onal, Zehra Esra
AU  - Onal ZE
AD  - Department of Pediatrics, Haydarpasa Numune Training and Research Hospital, 
      Istanbul, Turkey. Head of the Department: Cagatay Nuhoglu MD, Assoc. Prof.
FAU - Tabak, Yonca
AU  - Tabak Y
AD  - Department of Pediatrics, Haydarpasa Numune Training and Research Hospital, 
      Istanbul, Turkey. Head of the Department: Cagatay Nuhoglu MD, Assoc. Prof.
FAU - Nuhoglu, Cagatay
AU  - Nuhoglu C
AD  - Department of Pediatrics, Haydarpasa Numune Training and Research Hospital, 
      Istanbul, Turkey. Head of the Department: Cagatay Nuhoglu MD, Assoc. Prof.
FAU - Ceran, Omer
AU  - Ceran O
AD  - Department of Pediatrics, Haydarpasa Numune Training and Research Hospital, 
      Istanbul, Turkey. Head of the Department: Cagatay Nuhoglu MD, Assoc. Prof.
LA  - eng
PT  - Journal Article
DEP - 20150615
PL  - Poland
TA  - Postepy Dermatol Alergol
JT  - Postepy dermatologii i alergologii
JID - 101168357
PMC - PMC4495114
OTO - NOTNLM
OT  - in-utero sensitization
OT  - maternal immunoglobulin E
OT  - umbilical cord blood
EDAT- 2015/07/15 06:00
MHDA- 2015/07/15 06:01
PMCR- 2015/06/01
CRDT- 2015/07/11 06:00
PHST- 2014/05/04 00:00 [received]
PHST- 2014/06/12 00:00 [revised]
PHST- 2014/09/10 00:00 [accepted]
PHST- 2015/07/11 06:00 [entrez]
PHST- 2015/07/15 06:00 [pubmed]
PHST- 2015/07/15 06:01 [medline]
PHST- 2015/06/01 00:00 [pmc-release]
AID - 24301 [pii]
AID - 10.5114/pdia.2015.48051 [doi]
PST - ppublish
SO  - Postepy Dermatol Alergol. 2015 Jun;32(3):184-8. doi: 10.5114/pdia.2015.48051. 
      Epub 2015 Jun 15.