PMID- 26163706
OWN - NLM
STAT- MEDLINE
DCOM- 20161213
LR  - 20161230
IS  - 1878-4046 (Electronic)
IS  - 1076-6332 (Linking)
VI  - 22
IP  - 9
DP  - 2015 Sep
TI  - Automated tube voltage adaptation in combination with advanced modeled iterative 
      reconstruction in thoracoabdominal third-generation 192-slice dual-source 
      computed tomography: effects on image quality and radiation dose.
PG  - 1081-7
LID - S1076-6332(15)00248-2 [pii]
LID - 10.1016/j.acra.2015.05.010 [doi]
AB  - RATIONALE AND OBJECTIVES: To evaluate image quality and radiation exposure of 
      portal venous-phase thoracoabdominal third-generation 192-slice dual-source 
      computed tomography (DSCT) with automated tube voltage adaptation (TVA) in 
      combination with advanced modeled iterative reconstruction (ADMIRE). MATERIALS 
      AND METHODS: Fifty-one patients underwent oncologic portal venous-phase 
      thoracoabdominal follow-up CT twice within 7 months. The initial examination was 
      performed on second-generation 128-slice DSCT with fixed tube voltage of 120 kV 
      in combination with filtered back projection reconstruction. The second 
      examination was performed on a third-generation 192-slice DSCT using automated 
      TVA in combination with ADMIRE. Attenuation and image noise of liver, spleen, 
      renal cortex, aorta, vena cava inferior, portal vein, psoas muscle, and 
      perinephric fat were measured. Signal-to-noise ratio (SNR) and contrast-to-noise 
      ratio (CNR) were calculated. Radiation dose was assessed as size-specific dose 
      estimates (SSDE). Subjective image quality was assessed by two observers using 
      five-point Likert scales. Interobserver agreement was calculated using intraclass 
      correlation coefficients (ICC). RESULTS: Automated TVA set tube voltage to 90 kV 
      (n = 8), 100 kV (n = 31), 110 kV (n = 11), or 120 kV (n = 1). Average SSDE was 
      decreased by 34.9% using 192-slice DSCT compared to 128-slice 120-kV DSCT (7.8 +/- 
      2.4 vs. 12.1 +/- 3.2 mGy; P < .001). Image noise was substantially lower; SNR and 
      CNR were significantly increased in 192-slice DSCT compared to 128-slice DSCT 
      (all P < .005). Image quality was voted excellent for both acquisition techniques 
      (5.00 vs. 4.93; P = .083). CONCLUSIONS: Automated TVA in combination with ADMIRE 
      on third-generation 192-slice DSCT in portal venous-phase thoracoabdominal CT 
      provides excellent image quality with reduced image noise and increased SNR and 
      CNR, whereas average radiation dose is reduced by 34.9% compared to 128-slice 
      DSCT.
CI  - Copyright (c) 2015 AUR. Published by Elsevier Inc. All rights reserved.
FAU - Scholtz, Jan-Erik
AU  - Scholtz JE
AD  - Department of Diagnostic and Interventional Radiology, University Hospital 
      Frankfurt, Theodor-Stern-Kai 7, 60590 Frankfurt, Germany. Electronic address: 
      janerikscholtz@gmail.com.
FAU - Wichmann, Julian L
AU  - Wichmann JL
AD  - Department of Diagnostic and Interventional Radiology, University Hospital 
      Frankfurt, Theodor-Stern-Kai 7, 60590 Frankfurt, Germany.
FAU - Husers, Kristina
AU  - Husers K
AD  - Department of Diagnostic and Interventional Radiology, University Hospital 
      Frankfurt, Theodor-Stern-Kai 7, 60590 Frankfurt, Germany.
FAU - Beeres, Martin
AU  - Beeres M
AD  - Department of Diagnostic and Interventional Radiology, University Hospital 
      Frankfurt, Theodor-Stern-Kai 7, 60590 Frankfurt, Germany.
FAU - Nour-Eldin, Nour-Eldin Abdelrehim
AU  - Nour-Eldin NE
AD  - Department of Diagnostic and Interventional Radiology, University Hospital 
      Frankfurt, Theodor-Stern-Kai 7, 60590 Frankfurt, Germany; Diagnostic and 
      Interventional Radiology Department, Cairo University Hospital, Cairo, Egypt.
FAU - Frellesen, Claudia
AU  - Frellesen C
AD  - Department of Diagnostic and Interventional Radiology, University Hospital 
      Frankfurt, Theodor-Stern-Kai 7, 60590 Frankfurt, Germany.
FAU - Vogl, Thomas J
AU  - Vogl TJ
AD  - Department of Diagnostic and Interventional Radiology, University Hospital 
      Frankfurt, Theodor-Stern-Kai 7, 60590 Frankfurt, Germany.
FAU - Lehnert, Thomas
AU  - Lehnert T
AD  - Department of Diagnostic and Interventional Radiology, University Hospital 
      Frankfurt, Theodor-Stern-Kai 7, 60590 Frankfurt, Germany.
LA  - eng
PT  - Comparative Study
PT  - Journal Article
DEP - 20150709
PL  - United States
TA  - Acad Radiol
JT  - Academic radiology
JID - 9440159
RN  - 0 (Contrast Media)
SB  - IM
MH  - Adipose Tissue/diagnostic imaging
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Aortography/methods
MH  - Artifacts
MH  - Contrast Media
MH  - Female
MH  - Follow-Up Studies
MH  - Humans
MH  - Image Processing, Computer-Assisted/*methods
MH  - Kidney/diagnostic imaging
MH  - Kidney Cortex/diagnostic imaging
MH  - Liver/diagnostic imaging
MH  - Male
MH  - Middle Aged
MH  - Portography/methods
MH  - Psoas Muscles/diagnostic imaging
MH  - *Radiation Dosage
MH  - Radiographic Image Enhancement/methods
MH  - Radiography, Abdominal/*methods
MH  - Radiography, Thoracic/*methods
MH  - Retrospective Studies
MH  - Signal-To-Noise Ratio
MH  - Spleen/diagnostic imaging
MH  - Tomography, X-Ray Computed/*methods
MH  - Vena Cava, Inferior/diagnostic imaging
MH  - Young Adult
OTO - NOTNLM
OT  - Computed tomography
OT  - automated tube voltage adaptation
OT  - image quality
OT  - radiation dose
EDAT- 2015/07/15 06:00
MHDA- 2016/12/15 06:00
CRDT- 2015/07/13 06:00
PHST- 2015/03/27 00:00 [received]
PHST- 2015/05/20 00:00 [revised]
PHST- 2015/05/25 00:00 [accepted]
PHST- 2015/07/13 06:00 [entrez]
PHST- 2015/07/15 06:00 [pubmed]
PHST- 2016/12/15 06:00 [medline]
AID - S1076-6332(15)00248-2 [pii]
AID - 10.1016/j.acra.2015.05.010 [doi]
PST - ppublish
SO  - Acad Radiol. 2015 Sep;22(9):1081-7. doi: 10.1016/j.acra.2015.05.010. Epub 2015 
      Jul 9.