PMID- 26164686
OWN - NLM
STAT- MEDLINE
DCOM- 20161031
LR  - 20181202
IS  - 1876-4738 (Electronic)
IS  - 0914-5087 (Linking)
VI  - 67
IP  - 4
DP  - 2016 Apr
TI  - Assessment of atrial electromechanical delay and P-wave dispersion in patients 
      with type 2 diabetes mellitus.
PG  - 378-83
LID - S0914-5087(15)00185-9 [pii]
LID - 10.1016/j.jjcc.2015.06.003 [doi]
AB  - OBJECTIVES: Diabetes mellitus is an independent and strong risk factor for 
      development of atrial fibrillation (AF). Electrophysiologic and electromechanical 
      abnormalities are associated with a higher risk of AF. In this study we aimed to 
      determine the correlation of atrial conduction abnormalities between the surface 
      electrocardiographic and tissue Doppler echocardiographic measurements in type 2 
      diabetes mellitus (T2DM) patients. METHODS: A total of 88 consecutive T2DM 
      patients and 49 age-, gender-, and body mass index-matched healthy volunteers 
      were included in the present study. Baseline characteristics were recorded and 
      24-hour ambulatory blood pressure monitoring, transthoracic echocardiography, and 
      12-lead surface electrocardiography were performed for all study participants. 
      Atrial electromechanical delay (EMD) intervals were measured. RESULTS: Maximum 
      P-wave duration and P-wave dispersion (Pd) were significantly higher in patients 
      with T2DM (105.7+/-10.2ms vs. 102.2+/-7.5ms, p=0.02; 40.6+/-7.6ms vs. 33.6+/-5.9ms, 
      p<0.001, respectively). Interatrial, intraatrial, and intraleft atrial EMD were 
      significantly higher in the T2DM patients when compared with the controls 
      (16.5+/-7.8ms vs.11.2+/-4.4ms, p<0.001; 9.0+/-7.3ms vs. 6.0+/-3.8ms, p=0.002, and 
      7.4+/-5.2ms vs. 5.1+/-3.2ms, p=0.002 respectively). Correlation analysis showed a 
      positive correlation between interatrial EMD and Pd (r=0.429, p<0.001) and left 
      atrial volume (r=0.428, p<0.001). CONCLUSIONS: In this study, there was 
      significant EMD and Pd in patients with T2DM as compared with healthy volunteers. 
      Additionally, interatrial EMD was correlated with Pd and left atrial volume 
      index.
CI  - Copyright (c) 2015 Japanese College of Cardiology. Published by Elsevier Ltd. All 
      rights reserved.
FAU - Demir, Kenan
AU  - Demir K
AD  - Selcuk University Faculty of Medicine, Cardiology Department, Konya, Turkey. 
      Electronic address: drkenan76@yahoo.com.
FAU - Avci, Ahmet
AU  - Avci A
AD  - Selcuk University Faculty of Medicine, Cardiology Department, Konya, Turkey.
FAU - Kaya, Zeynettin
AU  - Kaya Z
AD  - Mevlana University Faculty of Medicine, Cardiology Department, Konya, Turkey.
FAU - Marakoglu, Kamile
AU  - Marakoglu K
AD  - Selcuk University Faculty of Medicine, Department of Family Medicine, Konya, 
      Turkey.
FAU - Ceylan, Esra
AU  - Ceylan E
AD  - Selcuk University Faculty of Medicine, Department of Family Medicine, Konya, 
      Turkey.
FAU - Yilmaz, Ahmet
AU  - Yilmaz A
AD  - Selcuk University Faculty of Medicine, Cardiology Department, Konya, Turkey.
FAU - Ersecgin, Ahmet
AU  - Ersecgin A
AD  - Selcuk University Faculty of Medicine, Cardiology Department, Konya, Turkey.
FAU - Armutlukuyu, Mustafa
AU  - Armutlukuyu M
AD  - Selcuk University Faculty of Medicine, Department of Family Medicine, Konya, 
      Turkey.
FAU - Altunkeser, Bulent Behlul
AU  - Altunkeser BB
AD  - Selcuk University Faculty of Medicine, Cardiology Department, Konya, Turkey.
LA  - eng
PT  - Journal Article
DEP - 20150709
PL  - Netherlands
TA  - J Cardiol
JT  - Journal of cardiology
JID - 8804703
SB  - IM
MH  - Adult
MH  - Atrial Fibrillation/*diagnostic imaging/etiology/physiopathology
MH  - Blood Pressure Monitoring, Ambulatory
MH  - Case-Control Studies
MH  - Diabetes Mellitus, Type 2/*complications/physiopathology
MH  - Echocardiography, Doppler/*methods
MH  - Electrocardiography/*methods
MH  - Female
MH  - Heart Atria/diagnostic imaging/physiopathology
MH  - Heart Conduction System/*diagnostic imaging/physiopathology
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Risk Factors
OTO - NOTNLM
OT  - Atrial electromechanical delay
OT  - Diabetes mellitus
OT  - P-wave dispersion
OT  - Tissue Doppler imaging
EDAT- 2015/07/15 06:00
MHDA- 2016/11/01 06:00
CRDT- 2015/07/13 06:00
PHST- 2015/03/31 00:00 [received]
PHST- 2015/06/04 00:00 [revised]
PHST- 2015/06/07 00:00 [accepted]
PHST- 2015/07/13 06:00 [entrez]
PHST- 2015/07/15 06:00 [pubmed]
PHST- 2016/11/01 06:00 [medline]
AID - S0914-5087(15)00185-9 [pii]
AID - 10.1016/j.jjcc.2015.06.003 [doi]
PST - ppublish
SO  - J Cardiol. 2016 Apr;67(4):378-83. doi: 10.1016/j.jjcc.2015.06.003. Epub 2015 Jul 
      9.