PMID- 26166018
OWN - NLM
STAT- MEDLINE
DCOM- 20160630
LR  - 20181113
IS  - 1473-5830 (Electronic)
IS  - 0954-6928 (Print)
IS  - 0954-6928 (Linking)
VI  - 26
IP  - 7
DP  - 2015 Nov
TI  - QRS duration: a novel marker of microvascular reperfusion as assessed by 
      myocardial blush grade in ST elevation myocardial infarction patients undergoing 
      a primary percutaneous intervention.
PG  - 583-6
LID - 10.1097/MCA.0000000000000285 [doi]
LID - 583-586
AB  - OBJECTIVES: Prolonged QRS duration is a predictor of poor prognosis in patients 
      with coronary artery disease. The association between the duration of QRS and 
      myocardial reperfusion is not very well understood. Our aim was to assess the 
      relationship between the measurements of QRS duration and myocardial blush grade 
      (MBG) in patients with ST elevation myocardial infarction (STEMI) who were 
      treated with a primary percutaneous intervention. PATIENTS AND METHODS: A total 
      of 213 patients (mean age: 57.5+/-11 years) with STEMI were included. ECG 
      recordings were obtained for the evaluation of the QRS duration before and after 
      primary percutaneous coronary intervention. Angiographic assessment in the 
      infarct-related artery was performed using the MBG. Patients were categorized 
      into two groups of those with impaired microvascular reperfusion (MBG: 0-1) and 
      those with normal microvascular reperfusion (MBG: 2-3). RESULTS: Overall, 105 and 
      108 patients had an MBG of 0-1 or 2-3, respectively. There is no significant 
      difference between patient's characteristics. Despite the absence of a difference 
      between two groups in terms of the QRS duration at presentation (P: 0.57), 
      patients with impaired microvascular reperfusion were found to have longer QRS 
      duration at immediately postprocedure (P: 0.003) and postprocedure 60 min 
      time-points (P<0.001). Correlation analyses showed a positive correlation between 
      pain-to-balloon time and QRS duration at postprocedure 60 min time-points (r: 
      0.137 and P: 0.04). CONCLUSION: Our results suggest that longer QRS duration 
      after angioplasty seemed to indicate the presence of impaired microvascular 
      reperfusion in patients with STEMI.
FAU - Karahan, Zulkuf
AU  - Karahan Z
AD  - Department of Cardiology, Gazi Yasargil Education and Research Hospital, 
      Diyarbakir, Turkey.
FAU - Yaylak, Baris
AU  - Yaylak B
FAU - Ugurlu, Murat
AU  - Ugurlu M
FAU - Kaya, Ilyas
AU  - Kaya I
FAU - Ucaman, Berzal
AU  - Ucaman B
FAU - Ozturk, Onder
AU  - Ozturk O
LA  - eng
PT  - Journal Article
PL  - England
TA  - Coron Artery Dis
JT  - Coronary artery disease
JID - 9011445
SB  - IM
MH  - Aged
MH  - Coronary Angiography
MH  - Coronary Artery Disease/*physiopathology/therapy
MH  - *Coronary Circulation
MH  - Electrocardiography
MH  - Female
MH  - Heart Conduction System/*physiopathology
MH  - Humans
MH  - Male
MH  - *Microcirculation
MH  - Microvessels/diagnostic imaging/*physiopathology
MH  - Middle Aged
MH  - Myocardial Infarction/diagnostic imaging/*physiopathology/therapy
MH  - *Myocardial Reperfusion
MH  - *Percutaneous Coronary Intervention
MH  - Prognosis
MH  - Time Factors
PMC - PMC4588599
EDAT- 2015/07/15 06:00
MHDA- 2016/07/01 06:00
PMCR- 2015/09/30
CRDT- 2015/07/14 06:00
PHST- 2015/07/14 06:00 [entrez]
PHST- 2015/07/15 06:00 [pubmed]
PHST- 2016/07/01 06:00 [medline]
PHST- 2015/09/30 00:00 [pmc-release]
AID - 10.1097/MCA.0000000000000285 [doi]
PST - ppublish
SO  - Coron Artery Dis. 2015 Nov;26(7):583-6. doi: 10.1097/MCA.0000000000000285.