PMID- 26170420 OWN - NLM STAT- MEDLINE DCOM- 20160810 LR - 20151027 IS - 1479-9731 (Electronic) IS - 1479-9723 (Linking) VI - 12 IP - 4 DP - 2015 Nov TI - Motor vehicle accidents and obstructive sleep apnea syndrome: A methodology to calculate the related burden of injuries. PG - 320-8 LID - 10.1177/1479972315594624 [doi] AB - The association between motor vehicle accidents (MVAs) and obstructive sleep apnea syndrome (OSAS) has always been quantified as risk of MVAs for individual drivers with OSAS. We evaluated the expected injured patients per year attributable to OSAS-dependent MVAs in a general population. By combining OSAS prevalence and OSAS-dependent MVAs odds ratio, we assessed the population attributable fraction (PAF), an epidemiological tool that can be used to quantify the proportion of road traffic injuries (RTIs) attributable to OSAS. For an apnea hypopnea index >5, the weighed median and combined average of OSAS prevalence were 4.4 (95% confidence interval (CI): 3.7-7.5) and 4.7 (95% CI: 4.2-5.2), respectively; values of risk of OSAS-dependent MVAs were 2.83 (95% CI: 2.72-3.08) and 2.52 (95% CI: 2.07-3.08), respectively. The PAF showed weighed median and combined average values of 6.6 (95% CI: 4.3-9.8) and 7.3% (95% CI: 6.0-13.5), respectively. Our results show that about 7% of RTIs for a population of male drivers involved in MVAs are attributable to OSAS. This value can be used to assess the potential impact, on the reduction of incidence of the motor vehicle injuries, of prevention programs aimed at reducing the number of subjects with an undiagnosed and/or untreated OSAS. CI - (c) The Author(s) 2015. FAU - Garbarino, Sergio AU - Garbarino S AD - Department of Neuroscience, Ophthalmology and Genetics, Sleep Medicine Center, University of Genoa, Genoa, Italy State Police Health Service Department, Ministry of the Interior, Rome, Italy. FAU - Pitidis, Alessio AU - Pitidis A AD - Department of Environment and Primary Prevention, Environment and Trauma Unit, National Institute of Health, Rome, Italy. FAU - Giustini, Marco AU - Giustini M AD - Department of Environment and Primary Prevention, Environment and Trauma Unit, National Institute of Health, Rome, Italy. FAU - Taggi, Franco AU - Taggi F AD - Department of Environment and Primary Prevention, Environment and Trauma Unit, National Institute of Health, Rome, Italy. FAU - Sanna, Antonio AU - Sanna A AD - Pneumology Unit, Azienda USL 3 Pistoia - Pneumology Unit, San Jacopo Hospital, Pistoia, Italy antonio.cagliari@live.it. LA - eng PT - Journal Article DEP - 20150713 PL - England TA - Chron Respir Dis JT - Chronic respiratory disease JID - 101197408 SB - IM MH - Accidents, Traffic/*statistics & numerical data MH - Causality MH - Humans MH - Male MH - Odds Ratio MH - Prevalence MH - Public Health MH - Severity of Illness Index MH - Sleep Apnea, Obstructive/*epidemiology MH - Wounds and Injuries/*epidemiology OTO - NOTNLM OT - Obstructive sleep apnea syndrome OT - motor vehicle accidents OT - population attributable fraction OT - public health OT - road traffic injuries EDAT- 2015/07/15 06:00 MHDA- 2016/08/11 06:00 CRDT- 2015/07/15 06:00 PHST- 2015/07/15 06:00 [entrez] PHST- 2015/07/15 06:00 [pubmed] PHST- 2016/08/11 06:00 [medline] AID - 1479972315594624 [pii] AID - 10.1177/1479972315594624 [doi] PST - ppublish SO - Chron Respir Dis. 2015 Nov;12(4):320-8. doi: 10.1177/1479972315594624. Epub 2015 Jul 13.