PMID- 26172229 OWN - NLM STAT- MEDLINE DCOM- 20170309 LR - 20191027 IS - 1606-7916 (Electronic) IS - 0036-3634 (Print) IS - 0036-3634 (Linking) VI - 57 Suppl 1 IP - 0 1 DP - 2015 TI - Prospective study of the link between overweight/obesity and diabetes incidence among Mexican older adults: 2001-2012. PG - S15-21 LID - S0036-36342015000700004 [pii] AB - OBJECTIVE: To prospectively assess the relationship between overweight/obesity and incidence of type 2 diabetes mellitus (T2DM) among Mexicans aged 50+, assessing effects of age, genetic predisposition, education, physical activity, and place of residence. MATERIALS AND METHODS: The Mexican Health and Aging Study (MHAS) was used to prospectively follow respondents free of diabetes in 2001 who became diabetic by 2012. Multivariate random effects logistic regression was used to assess covariates effects on the incidence of T2DM. RESULTS: Obese or overweight individuals at baseline (2001) were about 3 and 2 times, respectively, significantly more likely to become diabetic by 2012. Genetic predisposition increases the risk of diabetes by about three times compared to those with no family history of diabetes. CONCLUSION: Overweight/obesity and genetic predisposition are the primary drivers of diabetes incidence among Mexican older adults. Reducing body weight and having access to health care may amel iorate the disease burden of T2DM. FAU - Pinto, Guido AU - Pinto G AD - Center for Demography & Ecology, University of Wisconsin-Madison, Madison, Wisconsin, Estados Unidos de America. FAU - Beltran-Sanchez, Hiram AU - Beltran-Sanchez H AD - Center for Demography & Ecology, University of Wisconsin-Madison, Madison, Wisconsin, Estados Unidos de America. LA - eng GR - P30 AG017266/AG/NIA NIH HHS/United States GR - R01 AG018016/AG/NIA NIH HHS/United States PT - Journal Article PL - Mexico TA - Salud Publica Mex JT - Salud publica de Mexico JID - 0404371 SB - IM MH - Aged MH - Diabetes Mellitus, Type 2/*epidemiology MH - Female MH - Follow-Up Studies MH - Genetic Predisposition to Disease MH - Health Surveys MH - Humans MH - Incidence MH - Male MH - Mexico/epidemiology MH - Middle Aged MH - Morbidity/trends MH - Obesity/epidemiology MH - Overweight/*epidemiology MH - Prospective Studies MH - Risk Factors MH - Socioeconomic Factors PMC - PMC4711928 MID - NIHMS744895 EDAT- 2015/07/15 06:00 MHDA- 2017/03/10 06:00 PMCR- 2016/01/13 CRDT- 2015/07/15 06:00 PHST- 2013/12/09 00:00 [received] PHST- 2014/12/09 00:00 [accepted] PHST- 2015/07/15 06:00 [entrez] PHST- 2015/07/15 06:00 [pubmed] PHST- 2017/03/10 06:00 [medline] PHST- 2016/01/13 00:00 [pmc-release] AID - S0036-36342015000700004 [pii] AID - 10.21149/spm.v57s1.7585 [doi] PST - ppublish SO - Salud Publica Mex. 2015;57 Suppl 1(0 1):S15-21. doi: 10.21149/spm.v57s1.7585.