PMID- 26175197
OWN - NLM
STAT- MEDLINE
DCOM- 20160517
LR  - 20181113
IS  - 1432-1963 (Electronic)
IS  - 0172-8113 (Linking)
VI  - 36
IP  - 4
DP  - 2015 Jul
TI  - [Detection of the BCR-ABL fusion: Comparative analysis of six commercially 
      available FISH fusion probes].
PG  - 372-84
LID - 10.1007/s00292-015-0040-0 [doi]
AB  - Chronic myeloid leukemia (CML) is diagnostically defined by the reciprocal 
      translocation t(9;22)(q34;q11). This aberration can be detected by the BCR-ABL 
      fluorescence in situ hybridization (FISH) technique. This article presents a 
      comparative analysis of different commercially available FISH probes and 
      different FISH protocols in order to optimize this technique on formalin-fixed 
      and paraffin-embedded bone marrow trephine biopsies.
FAU - Knas, T
AU  - Knas T
AD  - Institut fur Pathologie, Universitatsklinikum Ulm, Albert-Einstein-Allee 23, 
      89081, Ulm, Deutschland.
FAU - Buck, M
AU  - Buck M
FAU - Stegelmann, F
AU  - Stegelmann F
FAU - Moller, P
AU  - Moller P
FAU - Barth, T F
AU  - Barth TF
LA  - ger
PT  - Comparative Study
PT  - English Abstract
PT  - Journal Article
TT  - Detektion der BCR-ABL-Fusion : Vergleichende Analyse sechs kommerzieller 
      FISH-Sondensatze.
PL  - Germany
TA  - Pathologe
JT  - Der Pathologe
JID - 8006541
RN  - EC 2.7.10.2 (Fusion Proteins, bcr-abl)
SB  - IM
MH  - Biopsy, Needle
MH  - Bone Marrow/*pathology
MH  - Chromosomes, Human, Pair 22
MH  - Chromosomes, Human, Pair 9
MH  - Fusion Proteins, bcr-abl/*analysis/*genetics
MH  - Humans
MH  - In Situ Hybridization, Fluorescence/instrumentation/*methods
MH  - Leukemia, Myelogenous, Chronic, BCR-ABL Positive/*genetics/*pathology
MH  - Sensitivity and Specificity
MH  - Translocation, Genetic
EDAT- 2015/07/16 06:00
MHDA- 2016/05/18 06:00
CRDT- 2015/07/16 06:00
PHST- 2015/07/16 06:00 [entrez]
PHST- 2015/07/16 06:00 [pubmed]
PHST- 2016/05/18 06:00 [medline]
AID - 10.1007/s00292-015-0040-0 [doi]
PST - ppublish
SO  - Pathologe. 2015 Jul;36(4):372-84. doi: 10.1007/s00292-015-0040-0.