PMID- 26175632
OWN - NLM
STAT- MEDLINE
DCOM- 20160505
LR  - 20181113
IS  - 1526-6702 (Electronic)
IS  - 0730-2347 (Print)
IS  - 0730-2347 (Linking)
VI  - 42
IP  - 3
DP  - 2015 Jun
TI  - Adjusted left atrial emptying fraction as a predictor of procedural outcome after 
      catheter ablation for atrial fibrillation.
PG  - 216-25
LID - 10.14503/THIJ-14-4524 [doi]
AB  - Structural remodeling of the left atrium is a risk factor for recurrent 
      arrhythmia after catheter ablation for atrial fibrillation; however, data are 
      sparse regarding the role of functional left atrial remodeling in predicting 
      procedural outcomes. We evaluated whether left atrial transport function could be 
      used to predict recurrent atrial fibrillation. From July 2008 through August 
      2010, we enrolled 202 consecutive patients who underwent catheter ablation for 
      atrial fibrillation (paroxysmal=120, persistent=82). Left atrial volumes (LAVs) 
      were measured by means of multislice computed tomography at every 10% of the R-R 
      interval, and measurements were adjusted for body surface area to yield the LAV 
      index (LAVI) at baseline. The left atrial emptying fraction (LAEF) was calculated 
      according to LAV differences. During the mean follow-up period of 10 +/- 4 months 
      after a single ablation procedure, atrial fibrillation recurred in 59 patients 
      (paroxysmal=19, persistent=40). Multivariate analysis revealed that persistent 
      atrial fibrillation, early mitral inflow velocity, LAVImax, LAVImin, LAEF, 
      LAVImax/LAEF, and LAVImin/LAEF were all independent predictors of atrial 
      fibrillation, but the best predictor was LAVImin/LAEF (beta=1.329, P=0.001). The 
      cutoff value was 1.61 (mL/m(2))/%, and the sensitivity and specificity were 74.6% 
      and 62.2%, respectively (area under the curve=0.761). Our study shows that 
      adjusted left atrial emptying fraction with use of multislice computed tomography 
      might be a useful, noninvasive method to select patients for ablation.
FAU - Im, Sung Il
AU  - Im SI
FAU - Na, Jin Oh
AU  - Na JO
FAU - Kim, Sun Won
AU  - Kim SW
FAU - Choi, Cheol Ung
AU  - Choi CU
FAU - Kim, Jin Won
AU  - Kim JW
FAU - Yong, Hwan Seok
AU  - Yong HS
FAU - Kim, Eung Ju
AU  - Kim EJ
FAU - Rha, Seung-Woon
AU  - Rha SW
FAU - Park, Chang Gyu
AU  - Park CG
FAU - Seo, Hong Seog
AU  - Seo HS
FAU - Oh, Dong Joo
AU  - Oh DJ
FAU - Lim, Hong Euy
AU  - Lim HE
LA  - eng
PT  - Journal Article
DEP - 20150601
PL  - United States
TA  - Tex Heart Inst J
JT  - Texas Heart Institute journal
JID - 8214622
SB  - IM
MH  - Atrial Fibrillation/diagnostic imaging/*physiopathology/*surgery
MH  - *Atrial Function, Left
MH  - *Catheter Ablation
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Multidetector Computed Tomography
MH  - Predictive Value of Tests
MH  - Prognosis
MH  - Prospective Studies
MH  - Recurrence
PMC - PMC4473613
OTO - NOTNLM
OT  - Atrial fibrillation/physiopathology
OT  - ROC curve
OT  - atrial function, left/physiology
OT  - cardiac volume
OT  - catheter ablation
OT  - heart atria/pathology/ultrasonography
OT  - predictive value of tests
OT  - preoperative care/methods
OT  - recurrence
OT  - tomography, X-ray computed/methods
EDAT- 2015/07/16 06:00
MHDA- 2016/05/06 06:00
PMCR- 2015/06/01
CRDT- 2015/07/16 06:00
PHST- 2015/07/16 06:00 [entrez]
PHST- 2015/07/16 06:00 [pubmed]
PHST- 2016/05/06 06:00 [medline]
PHST- 2015/06/01 00:00 [pmc-release]
AID - 10.14503/THIJ-14-4524 [doi]
PST - epublish
SO  - Tex Heart Inst J. 2015 Jun 1;42(3):216-25. doi: 10.14503/THIJ-14-4524. 
      eCollection 2015 Jun.