PMID- 26179854 OWN - NLM STAT- MEDLINE DCOM- 20170824 LR - 20181202 IS - 1989-4805 (Electronic) IS - 1889-1837 (Linking) VI - 32 IP - 1 DP - 2015 Jan-Mar TI - [The association of hyperinsulinemia with cardiovascular risk and cancer poses new challenges in the treatment of the insulin resistance type 2 diabetes patient]. PG - 21-6 LID - S1889-1837(14)00061-0 [pii] LID - 10.1016/j.hipert.2014.06.001 [doi] AB - Hyperinsulinemia has been associated with cardiovascular risk, both independently and by facilitating the development of other cardiovascular risk factors. It has also been associated by different routes with increased cancer risk. Thus, this makes it a priority to identify and treat the hyperinsulinemic patient early in order to delay or prevent cardiovascular risk and the development of type 2 diabetes mellitus (T2DM) and certain types of cancer. A new strategy is needed for the treatment of hyperglycemia in these patients, whose primary objective would be to achieve weight loss, reduce insulin resistance and thereby hyperinsulinemia. That is, prescribing insulin secretors and insulin should be used with caution in these patients. CI - Copyright (c) 2014 SEHLELHA. Published by Elsevier Espana. All rights reserved. FAU - Nubiola, Andreu AU - Nubiola A AD - Unitat d́Endocrinologia, Servei de Medicina Interna, Hospital Universitari de LEsperit Sant, Santa Coloma de Gramenet, Barcelona, Espana. Electronic address: anubiola@hes.scs.es. FAU - Ferrer, Marga AU - Ferrer M AD - Unitat d́Endocrinologia, Servei de Medicina Interna, Hospital Universitari de LEsperit Sant, Santa Coloma de Gramenet, Barcelona, Espana. FAU - Remolins, Imma AU - Remolins I AD - Unitat de Nutricio, PAMEM (IMAS), Barcelona, Espana. LA - spa PT - Journal Article TT - La asociacion de hiperinsulinemia con riesgo cardiovascular y cancer plantea nuevos retos en el abordaje del paciente con diabetes tipo 2, insulinorresistente. DEP - 20140715 PL - Spain TA - Hipertens Riesgo Vasc JT - Hipertension y riesgo vascular JID - 101510649 SB - IM MH - *Cardiovascular Diseases MH - *Diabetes Mellitus, Type 2 MH - Humans MH - Hyperinsulinism MH - *Insulin Resistance MH - Neoplasms MH - Risk Factors OTO - NOTNLM OT - Cancer OT - Cardiovascular OT - Cancer OT - Diabetes tipo 2 OT - Hiperinsulinemia OT - Hyperinsulinemia OT - Insulin resistance OT - Insulinorresistencia OT - Type 2 diabetes EDAT- 2015/07/17 06:00 MHDA- 2017/08/25 06:00 CRDT- 2015/07/17 06:00 PHST- 2014/06/12 00:00 [received] PHST- 2014/06/14 00:00 [revised] PHST- 2014/06/16 00:00 [accepted] PHST- 2015/07/17 06:00 [entrez] PHST- 2015/07/17 06:00 [pubmed] PHST- 2017/08/25 06:00 [medline] AID - S1889-1837(14)00061-0 [pii] AID - 10.1016/j.hipert.2014.06.001 [doi] PST - ppublish SO - Hipertens Riesgo Vasc. 2015 Jan-Mar;32(1):21-6. doi: 10.1016/j.hipert.2014.06.001. Epub 2014 Jul 15.