PMID- 26189673
OWN - NLM
STAT- MEDLINE
DCOM- 20151103
LR  - 20181202
IS  - 1873-3778 (Electronic)
IS  - 0021-9673 (Linking)
VI  - 1408
DP  - 2015 Aug 21
TI  - Ionic liquid-molecularly imprinted polymers for pipette tip solid-phase 
      extraction of (Z)-3-(chloromethylene)-6-flourothiochroman-4-one in urine.
PG  - 49-55
LID - S0021-9673(15)00979-6 [pii]
LID - 10.1016/j.chroma.2015.07.028 [doi]
AB  - A new type of ionic liquid-molecularly imprinted polymers (IL-MIPs) synthesized 
      by precipitation polymerization using 1-allyl-3-methylimidazolium bromide and 
      acrylamide as co-functional monomers and 
      (Z)-6-fluoro-3-(hydroxymethylene)-thiochroman-4-one (FHO) as dummy template was 
      successfully applied as a selective adsorbent of pipette tip solid-phase 
      extraction (PT-SPE) for rapid extraction and determination of 
      (Z)-3-(chloromethylene)-6-flourothiochroman-4-one (CFO) in urine. The factors 
      that affected the extraction efficiency including amounts of adsorbent, types of 
      washing solvent, and types and volumes of elution solvent were optimized. Under 
      the optimum conditions of ionic liquid-molecularly imprinted polymers-pipette tip 
      solid-phase extraction (IL-MIPs-PT-SPE) coupled with HPLC-UV, good linearity for 
      CFO was achieved in a range of 0.1-10.0mugmL(-1) (r=0.9999) and the recoveries at 
      three spiked levels were ranged from 94.8% to 103.4% with the relative standard 
      deviations (RSDs) less than 5.7% (n=3).
CI  - Copyright (c) 2015 Elsevier B.V. All rights reserved.
FAU - Yuan, Yanan
AU  - Yuan Y
AD  - Key Laboratory of Pharmaceutical Quality Control of Hebei Province & College of 
      Pharmacy, Key Laboratory of Medicinal Chemistry and Molecular Diagnosis, Ministry 
      of Education, Hebei University, Baoding 071002, China.
FAU - Liang, Shiru
AU  - Liang S
AD  - Key Laboratory of Pharmaceutical Quality Control of Hebei Province & College of 
      Pharmacy, Key Laboratory of Medicinal Chemistry and Molecular Diagnosis, Ministry 
      of Education, Hebei University, Baoding 071002, China.
FAU - Yan, Hongyuan
AU  - Yan H
AD  - Key Laboratory of Pharmaceutical Quality Control of Hebei Province & College of 
      Pharmacy, Key Laboratory of Medicinal Chemistry and Molecular Diagnosis, Ministry 
      of Education, Hebei University, Baoding 071002, China. Electronic address: 
      yanhy@hbu.edu.cn.
FAU - Ma, Zhengyue
AU  - Ma Z
AD  - Key Laboratory of Pharmaceutical Quality Control of Hebei Province & College of 
      Pharmacy, Key Laboratory of Medicinal Chemistry and Molecular Diagnosis, Ministry 
      of Education, Hebei University, Baoding 071002, China.
FAU - Liu, Yuxin
AU  - Liu Y
AD  - Key Laboratory of Pharmaceutical Quality Control of Hebei Province & College of 
      Pharmacy, Key Laboratory of Medicinal Chemistry and Molecular Diagnosis, Ministry 
      of Education, Hebei University, Baoding 071002, China.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20150710
PL  - Netherlands
TA  - J Chromatogr A
JT  - Journal of chromatography. A
JID - 9318488
RN  - 0 (1-allyl-3-methylimidazolium)
RN  - 0 (3-(chloromethylene)-6-flourothiochroman-4-one)
RN  - 0 (Allyl Compounds)
RN  - 0 (Antineoplastic Agents)
RN  - 0 (Chromans)
RN  - 0 (Imidazoles)
RN  - 0 (Ionic Liquids)
RN  - 0 (Polymers)
RN  - 20R035KLCI (Acrylamide)
SB  - IM
MH  - Acrylamide/*chemistry
MH  - Allyl Compounds/*chemistry
MH  - Antineoplastic Agents/chemistry/*urine
MH  - Chromans/chemistry/*urine
MH  - Chromatography, High Pressure Liquid
MH  - Humans
MH  - Imidazoles/*chemistry
MH  - *Ionic Liquids
MH  - Molecular Imprinting
MH  - Polymerization
MH  - Polymers/chemical synthesis
MH  - Solid Phase Extraction/methods
MH  - Stereoisomerism
OTO - NOTNLM
OT  - (Z)-3-(chloromethylene)-6-flourothiochroman-4-one
OT  - Ionic liquid-molecularly imprinted polymers
OT  - Pipette tip solid-phase extraction
OT  - Urine
EDAT- 2015/07/21 06:00
MHDA- 2015/11/04 06:00
CRDT- 2015/07/21 06:00
PHST- 2015/05/28 00:00 [received]
PHST- 2015/07/06 00:00 [revised]
PHST- 2015/07/08 00:00 [accepted]
PHST- 2015/07/21 06:00 [entrez]
PHST- 2015/07/21 06:00 [pubmed]
PHST- 2015/11/04 06:00 [medline]
AID - S0021-9673(15)00979-6 [pii]
AID - 10.1016/j.chroma.2015.07.028 [doi]
PST - ppublish
SO  - J Chromatogr A. 2015 Aug 21;1408:49-55. doi: 10.1016/j.chroma.2015.07.028. Epub 
      2015 Jul 10.