PMID- 26192998 OWN - NLM STAT- MEDLINE DCOM- 20171214 LR - 20191008 IS - 1522-2594 (Electronic) IS - 0740-3194 (Print) IS - 0740-3194 (Linking) VI - 75 IP - 6 DP - 2016 Jun TI - Sensitivity Enhancement of an Inductively Coupled Local Detector Using a HEMT-Based Current Amplifier. PG - 2573-8 LID - 10.1002/mrm.25850 [doi] AB - PURPOSE: To improve the signal transmission efficiency and sensitivity of a local detection coil that is weakly inductively coupled to a larger receive coil. METHODS: The resonant detection coil is connected in parallel with the gate of a high electron mobility transistor (HEMT) transistor without impedance matching. When the drain of the transistor is capacitively shunted to ground, current amplification occurs in the resonator by feedback that transforms a capacitive impedance on the transistor's source to a negative resistance on its gate. RESULTS: High resolution images were obtained from a mouse brain using a small, 11 mm diameter surface coil that was inductively coupled to a commercial, phased array chest coil. Although the power consumption of the amplifier was only 88 muW, 14 dB gain was obtained with excellent noise performance. CONCLUSION: An integrated current amplifier based on a HEMT can enhance the sensitivity of inductively coupled local detectors when weakly coupled. This amplifier enables efficient signal transmission between customized user coils and commercial clinical coils, without the need for a specialized signal interface. Magn Reson Med 75:2573-2578, 2016. Published 2015. This article is a U.S. Government work and is in the public domain in the USA. CI - Published 2015 This article is a U.S. Government work and is in the public domain in the USA. FAU - Qian, Chunqi AU - Qian C AD - Laboratory of Functional and Molecular Imaging, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, USA. AD - Department of Radiology, Michigan State University, East Lansing, Michigan, USA. FAU - Duan, Qi AU - Duan Q AD - Laboratory of Functional and Molecular Imaging, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, USA. FAU - Dodd, Steve AU - Dodd S AD - Laboratory of Functional and Molecular Imaging, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, USA. FAU - Koretsky, Alan AU - Koretsky A AD - Laboratory of Functional and Molecular Imaging, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, USA. FAU - Murphy-Boesch, Joe AU - Murphy-Boesch J AD - Laboratory of Functional and Molecular Imaging, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, USA. LA - eng GR - R00 EB016753/EB/NIBIB NIH HHS/United States GR - Z99 NS999999/Intramural NIH HHS/United States PT - Journal Article DEP - 20150720 PL - United States TA - Magn Reson Med JT - Magnetic resonance in medicine JID - 8505245 SB - IM MH - *Amplifiers, Electronic MH - Animals MH - Equipment Design MH - Image Processing, Computer-Assisted/*methods MH - Magnetic Resonance Imaging/*instrumentation/*methods MH - Mice MH - Signal Processing, Computer-Assisted/*instrumentation PMC - PMC4720591 MID - NIHMS706089 OTO - NOTNLM OT - HEMT OT - MRI OT - current amplifier OT - inductive coupling OT - negative resistance EDAT- 2015/07/21 06:00 MHDA- 2017/12/15 06:00 PMCR- 2017/06/01 CRDT- 2015/07/21 06:00 PHST- 2015/04/20 00:00 [received] PHST- 2015/06/12 00:00 [revised] PHST- 2015/06/27 00:00 [accepted] PHST- 2015/07/21 06:00 [entrez] PHST- 2015/07/21 06:00 [pubmed] PHST- 2017/12/15 06:00 [medline] PHST- 2017/06/01 00:00 [pmc-release] AID - 10.1002/mrm.25850 [doi] PST - ppublish SO - Magn Reson Med. 2016 Jun;75(6):2573-8. doi: 10.1002/mrm.25850. Epub 2015 Jul 20.