PMID- 26202159 OWN - NLM STAT- MEDLINE DCOM- 20160913 LR - 20191210 IS - 1875-8312 (Electronic) IS - 1569-5794 (Linking) VI - 31 Suppl 2 DP - 2015 Dec TI - Diagnostic accuracy of late iodine enhancement on cardiac computed tomography with a denoise filter for the evaluation of myocardial infarction. PG - 177-85 LID - 10.1007/s10554-015-0716-9 [doi] AB - We evaluated the image quality and diagnostic performance of late iodine enhancement (LIE) in dual-source computed tomography (DSCT) with low kilo-voltage peak (kVp) images and a denoise filter for the detection of acute myocardial infarction (AMI) in comparison with late gadolinium enhancement (LGE) magnetic resonance imaging (MRI). The Hospital Ethics Committee approved the study protocol. Before discharge, 19 patients who received percutaneous coronary intervention after AMI underwent DSCT and 1.5 T MRI. Immediately after coronary computed tomography (CT) angiography, contrast medium was administered at a slow injection rate. LIE-CT scans were acquired via dual-energy CT and reconstructed as 100-, 140-kVp, and mixed images. An iterative three-dimensional edge-preserved smoothing filter was applied to the 100-kVp images to obtain denoised 100-kVp images. The mixed, 140-kVp, 100-kVp, and denoised 100-kVp images were assessed using contrast-to-noise ratio (CNR), and their diagnostic performance in comparison with MRI and infarcted volumes were evaluated. Three hundred four segments of 19 patients were evaluated. Fifty-three segments showed LGE in MRI. The median CNR of the mixed, 140-, 100-kVp and denoised 100-kVp images was 3.49, 1.21, 3.57, and 6.08, respectively. The median CNR was significantly higher in the denoised 100-kVp images than in the other three images (P < 0.05). The denoised 100-kVp images showed the highest diagnostic accuracy and sensitivity. The percentage of myocardium in the four CT image types was significantly correlated with the respective MRI findings. The use of a denoise filter with a low-kVp image can improve CNR, sensitivity, and accuracy in LIE-CT. FAU - Matsuda, Takuya AU - Matsuda T AD - Department of Radiology, Ehime University Graduate School of Medicine, Shitsukawa, Toon, Ehime, 791-0295, Japan. tmatsuda.singing@gmail.com. FAU - Kido, Teruhito AU - Kido T AD - Department of Radiology, Ehime University Graduate School of Medicine, Shitsukawa, Toon, Ehime, 791-0295, Japan. FAU - Itoh, Toshihide AU - Itoh T AD - Research and Collaboration, Siemens Japan, Shinagawa, Tokyo, Japan. FAU - Saeki, Hideyuki AU - Saeki H AD - Department of Cardiology, Saiseikai Matsuyama Hospital, Matsuyama, Ehime, Japan. FAU - Shigemi, Susumu AU - Shigemi S AD - Department of Cardiology, Saiseikai Matsuyama Hospital, Matsuyama, Ehime, Japan. FAU - Watanabe, Kouki AU - Watanabe K AD - Department of Cardiology, Saiseikai Matsuyama Hospital, Matsuyama, Ehime, Japan. FAU - Kido, Tomoyuki AU - Kido T AD - Department of Radiology, Saiseikai Matsuyama Hospital, Matsuyama, Ehime, Japan. FAU - Aono, Shoji AU - Aono S AD - Department of Radiology, Saiseikai Matsuyama Hospital, Matsuyama, Ehime, Japan. FAU - Yamamoto, Masaya AU - Yamamoto M AD - Department of Radiology, Saiseikai Matsuyama Hospital, Matsuyama, Ehime, Japan. FAU - Matsuda, Takeshi AU - Matsuda T AD - Department of Radiology, Matsuyama Red Cross Hospital, Matsuyama, Ehime, Japan. FAU - Mochizuki, Teruhito AU - Mochizuki T AD - Department of Radiology, Ehime University Graduate School of Medicine, Shitsukawa, Toon, Ehime, 791-0295, Japan. LA - eng PT - Comparative Study PT - Evaluation Study PT - Journal Article DEP - 20150723 PL - United States TA - Int J Cardiovasc Imaging JT - The international journal of cardiovascular imaging JID - 100969716 RN - 0 (Contrast Media) RN - JR13W81H44 (Iopamidol) RN - K2I13DR72L (Gadolinium DTPA) SB - IM MH - Aged MH - Aged, 80 and over MH - Contrast Media/*administration & dosage MH - Equipment Design MH - Female MH - Gadolinium DTPA/*administration & dosage MH - Humans MH - Iopamidol/*administration & dosage MH - *Magnetic Resonance Imaging MH - Male MH - Middle Aged MH - Myocardial Infarction/*diagnostic imaging/*pathology MH - Myocardium/*pathology MH - Predictive Value of Tests MH - Prospective Studies MH - Radiographic Image Interpretation, Computer-Assisted/*methods MH - Reproducibility of Results MH - Tissue Survival MH - Tomography, X-Ray Computed/*methods OTO - NOTNLM OT - Acute myocardial infarction OT - Cardiac computed tomography OT - Image postprocessing OT - Late iodine enhancement EDAT- 2015/07/24 06:00 MHDA- 2016/09/14 06:00 CRDT- 2015/07/24 06:00 PHST- 2015/07/09 00:00 [received] PHST- 2015/07/16 00:00 [accepted] PHST- 2015/07/24 06:00 [entrez] PHST- 2015/07/24 06:00 [pubmed] PHST- 2016/09/14 06:00 [medline] AID - 10.1007/s10554-015-0716-9 [pii] AID - 10.1007/s10554-015-0716-9 [doi] PST - ppublish SO - Int J Cardiovasc Imaging. 2015 Dec;31 Suppl 2:177-85. doi: 10.1007/s10554-015-0716-9. Epub 2015 Jul 23.