PMID- 26203235
OWN - NLM
STAT- MEDLINE
DCOM- 20160419
LR  - 20181113
IS  - 1178-1998 (Electronic)
IS  - 1176-9092 (Print)
IS  - 1176-9092 (Linking)
VI  - 10
DP  - 2015
TI  - Agreement for depression diagnosis between DSM-IV-TR criteria, three validated 
      scales, oncologist assessment, and psychiatric clinical interview in elderly 
      patients with advanced ovarian cancer.
PG  - 1155-62
LID - 10.2147/CIA.S71690 [doi]
AB  - BACKGROUND: Depression, a major outcome in cancer patients, is often evaluated by 
      physicians relying on their clinical impressions rather than patient self-report. 
      Our aim was to assess agreement between patient self-reported depression, 
      oncologist assessment (OA), and psychiatric clinical interview (PCI) in elderly 
      patients with advanced ovarian cancer (AOC). METHODS: This analysis was a 
      secondary endpoint of the Elderly Women AOC Trial 3 (EWOT3), designed to assess 
      the impact of geriatric covariates, notably depression, on survival in patients 
      older than 70 years of age. Depression was assessed using the Geriatric 
      Depression Scale-30 (GDS), the Hospital Anxiety Depression Scale, the distress 
      thermometer, the mood thermometer, and OA. The interview guide for PCI was 
      constructed from three validated scales: the GDS, the Hamilton Depression Rating 
      Scale, and the Montgomery Asberg Depression Rating Scale (MADRS). The Diagnostic 
      and Statistical Manual of Mental Disorders, fourth edition, revised (DSM) 
      criteria for depression were used as a gold standard. RESULTS: Out of 109 
      patients enrolled at 21 centers, 99 (91%) completed all the assessments. Patient 
      characteristics were: mean age 78, performance status >/=2: 47 (47%). Thirty six 
      patients (36%) were identified as depressed by the PCI versus 15 (15%) identified 
      by DSM. We found moderate agreement for depression identification between DSM and 
      GDS (kappa=0.508) and PCI (kappa=0.431) and high agreement with MADRS (kappa=0.663). We found 
      low or no agreement between DSM with the other assessment strategies, including 
      OA (kappa=-0.043). Identification according to OA (yes/no) resulted in a 
      false-negative rate of 87%. As a screening tool, GDS had the best sensitivity and 
      specificity (94% and 80%, respectively). CONCLUSION: The use of validated tools, 
      such as GDS, and collaboration between psychologists and oncologists are 
      warranted to better identify emotional disorders in elderly women with AOC.
FAU - Rhondali, Wadih
AU  - Rhondali W
AD  - Clinique Mon Repos, Clinea, Marseille, France.
FAU - Freyer, Gilles
AU  - Freyer G
AD  - Medical Oncology Unit, Centre Hospitalier Lyon Sud, Universite Lyon 1, 
      Pierre-Benite, France.
FAU - Adam, Virginie
AU  - Adam V
AD  - Institut de Cancerologie de Lorraine Alexis Vautrin, Vandoeuvreles-Nancy, France.
FAU - Filbet, Marilene
AU  - Filbet M
AD  - Palliative Unit, Centre Hospitalier Lyon Sud, Universite Lyon 1, Pierre-Benite, 
      France.
FAU - Derzelle, Martine
AU  - Derzelle M
AD  - Institut Jean Godinot, Reims, France.
FAU - Abgrall-Barbry, Gaelle
AU  - Abgrall-Barbry G
AD  - Tenon Hospital, Assistance Publique Hopitaux de Paris, Paris, France.
FAU - Bourcelot, Sophie
AU  - Bourcelot S
AD  - Centre Leon Berard, Lyon, France.
FAU - Machavoine, Jean-Louis
AU  - Machavoine JL
AD  - Centre Francois Baclesse, Caen, France.
FAU - Chomat-Neyraud, Muriel
AU  - Chomat-Neyraud M
AD  - Centre Hospitalier de la region d'Annecy, Pringy, France.
FAU - Gisserot, Olivier
AU  - Gisserot O
AD  - Hopital d'Instruction des Armees Sainte-Anne, Toulon, France.
FAU - Largillier, Remi
AU  - Largillier R
AD  - Centre Azureen de Cancerologie, Mougins, France.
FAU - Le Rol, Annick
AU  - Le Rol A
AD  - Medical Oncology, Hopital Perpetuel Secours, Levallois-Perret, France.
FAU - Priou, Frank
AU  - Priou F
AD  - Medical Oncology, Centre Hospitalier Departemental Les Oudairies, La 
      Roche-sur-Yon, France.
FAU - Saltel, Pierre
AU  - Saltel P
AD  - Supportive Care Department, Centre Leon Berard, Lyon, France.
FAU - Falandry, Claire
AU  - Falandry C
AD  - Geriatrics and Oncology Unit, Centre Hospitalier Lyon Sud, Universite Lyon 1, 
      Pierre-Benite, France.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20150713
PL  - New Zealand
TA  - Clin Interv Aging
JT  - Clinical interventions in aging
JID - 101273480
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - Depression/*psychology
MH  - Diagnostic and Statistical Manual of Mental Disorders
MH  - Female
MH  - Geriatric Assessment/methods
MH  - Humans
MH  - Interviews as Topic
MH  - Medical Oncology/*methods
MH  - Ovarian Neoplasms/mortality/*psychology
MH  - Psychiatric Status Rating Scales/*standards
MH  - Reproducibility of Results
MH  - Self Report/*standards
MH  - Sensitivity and Specificity
PMC - PMC4506027
OTO - NOTNLM
OT  - cancer
OT  - depression
OT  - elderly
OT  - geriatric assessment
OT  - screening
EDAT- 2015/07/24 06:00
MHDA- 2016/04/20 06:00
PMCR- 2015/07/13
CRDT- 2015/07/24 06:00
PHST- 2015/07/24 06:00 [entrez]
PHST- 2015/07/24 06:00 [pubmed]
PHST- 2016/04/20 06:00 [medline]
PHST- 2015/07/13 00:00 [pmc-release]
AID - cia-10-1155 [pii]
AID - 10.2147/CIA.S71690 [doi]
PST - epublish
SO  - Clin Interv Aging. 2015 Jul 13;10:1155-62. doi: 10.2147/CIA.S71690. eCollection 
      2015.