PMID- 26210162
OWN - NLM
STAT- MEDLINE
DCOM- 20160317
LR  - 20181113
IS  - 1756-0500 (Electronic)
IS  - 1756-0500 (Linking)
VI  - 8
DP  - 2015 Jul 26
TI  - Assessment of adverse events via a telephone consultation service for cancer 
      patients receiving ambulatory chemotherapy.
PG  - 315
LID - 10.1186/s13104-015-1292-8 [doi]
LID - 315
AB  - BACKGROUND: An increasing number of cancer patients are receiving ambulatory 
      chemotherapy to improve their quality of life and reduce medical expenses. During 
      outpatient chemotherapy, adverse events (AEs) occurring at home must be carefully 
      monitored. We investigated the use of our institution's telephone consultation 
      service that is available to patients and their caregivers for advice on and the 
      management of AEs and complications arising from cancer treatment. PATIENTS AND 
      METHODS: Telephone consultants assessed and graded AEs according to the Common 
      Terminology Criteria for Adverse Events (CTCAE). All patient characteristics, 
      AEs, and background factors were analyzed using logistic regression analyses. 
      RESULTS: Between August 2011 and August 2012, we included 253 patients and 344 
      telephone consultations regarding AEs during chemotherapy for analysis in this 
      study. Grade 1 AEs were assessed in 223 consultations (65%); grade 2 AEs, in 90 
      consultations (26%); and grade 3 AEs, in 31 consultations (9%). A multivariate 
      logistic regression analysis revealed an association between a change in patient 
      schedules and the occurrence of grade 2 or worse AEs (Hazard ratio = 6.58, P < 
      0.001). Changes in planned chemotherapy occurred more often in cases involving 
      male patients (Hazard ratio = 2.70, P = 0.02) and in cases of grade 2 or worse 
      AEs (Hazard ratio = 6.58, P < 0.001). CONCLUSION: We found that AE assessment 
      using CTCAE via a telephone consultation service is useful for both the triage of 
      patients and the prediction of severe AEs that may change clinical schedules.
FAU - Kondo, Shunsuke
AU  - Kondo S
AD  - Outpatient Treatment Center, National Cancer Center Hospital, 5-1-1 Tsukiji 
      Chuo-ku, Tokyo, 104-0045, Japan. shkondo@ncc.go.jp.
FAU - Shiba, Satoshi
AU  - Shiba S
AD  - Outpatient Treatment Center, National Cancer Center Hospital, 5-1-1 Tsukiji 
      Chuo-ku, Tokyo, 104-0045, Japan. sashiba@ncc.go.jp.
FAU - Udagawa, Ryoko
AU  - Udagawa R
AD  - Outpatient Treatment Center, National Cancer Center Hospital, 5-1-1 Tsukiji 
      Chuo-ku, Tokyo, 104-0045, Japan. ryudagaw@east.ncc.go.jp.
FAU - Ryushima, Yasuaki
AU  - Ryushima Y
AD  - Outpatient Treatment Center, National Cancer Center Hospital, 5-1-1 Tsukiji 
      Chuo-ku, Tokyo, 104-0045, Japan. yryshim@east.ncc.go.jp.
FAU - Yano, Miho
AU  - Yano M
AD  - Outpatient Treatment Center, National Cancer Center Hospital, 5-1-1 Tsukiji 
      Chuo-ku, Tokyo, 104-0045, Japan. mhsuzuki@ncc.go.jp.
FAU - Uehara, Tomoko
AU  - Uehara T
AD  - Outpatient Treatment Center, National Cancer Center Hospital, 5-1-1 Tsukiji 
      Chuo-ku, Tokyo, 104-0045, Japan. tmuehara@ncc.go.jp.
FAU - Asanabe, Mihoko
AU  - Asanabe M
AD  - Outpatient Treatment Center, National Cancer Center Hospital, 5-1-1 Tsukiji 
      Chuo-ku, Tokyo, 104-0045, Japan. masanabe@ncc.go.jp.
FAU - Tamura, Kenji
AU  - Tamura K
AD  - Outpatient Treatment Center, National Cancer Center Hospital, 5-1-1 Tsukiji 
      Chuo-ku, Tokyo, 104-0045, Japan. ketamura@ncc.go.jp.
FAU - Hashimoto, Jun
AU  - Hashimoto J
AD  - Outpatient Treatment Center, National Cancer Center Hospital, 5-1-1 Tsukiji 
      Chuo-ku, Tokyo, 104-0045, Japan. juhashim@ncc.go.jp.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20150726
PL  - England
TA  - BMC Res Notes
JT  - BMC research notes
JID - 101462768
RN  - 0 (Antineoplastic Agents)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Antineoplastic Agents/administration & dosage/*adverse effects
MH  - Disease Management
MH  - Drug Administration Schedule
MH  - Female
MH  - Humans
MH  - Logistic Models
MH  - Male
MH  - Middle Aged
MH  - Neoplasms/drug therapy/pathology/*psychology
MH  - Outpatients
MH  - Quality of Life/*psychology
MH  - Referral and Consultation/*statistics & numerical data
MH  - Telephone
MH  - Triage/*statistics & numerical data
PMC - PMC4514970
EDAT- 2015/07/27 06:00
MHDA- 2016/03/18 06:00
PMCR- 2015/07/26
CRDT- 2015/07/27 06:00
PHST- 2014/05/20 00:00 [received]
PHST- 2015/07/22 00:00 [accepted]
PHST- 2015/07/27 06:00 [entrez]
PHST- 2015/07/27 06:00 [pubmed]
PHST- 2016/03/18 06:00 [medline]
PHST- 2015/07/26 00:00 [pmc-release]
AID - 10.1186/s13104-015-1292-8 [pii]
AID - 1292 [pii]
AID - 10.1186/s13104-015-1292-8 [doi]
PST - epublish
SO  - BMC Res Notes. 2015 Jul 26;8:315. doi: 10.1186/s13104-015-1292-8.