PMID- 26215493 OWN - NLM STAT- MEDLINE DCOM- 20160601 LR - 20190221 IS - 1879-291X (Electronic) IS - 0301-5629 (Linking) VI - 41 IP - 10 DP - 2015 Oct TI - Ultrasonographic Features of the Major Salivary Glands after Radioactive Iodine Ablation in Patients with Papillary Thyroid Carcinoma. PG - 2640-5 LID - S0301-5629(15)00408-1 [pii] LID - 10.1016/j.ultrasmedbio.2015.06.010 [doi] AB - The aim of this study was to evaluate the ultrasonographic features of the major salivary glands (MSGs) after post-operative radioactive iodine ablation (RIA) in patients with papillary thyroid carcinoma (PTC). The study population comprised 202 consecutively registered PTC patients who had undergone total thyroidectomy, RIA and follow-up neck ultrasonography. The ultrasonographic features of the MSGs in each patient were retrospectively evaluated by a single radiologist, and the presence of post-RIA changes was determined by direct comparisons of pre- and post-RIA follow-up ultrasonographic scans. Of the 202 patients, 94 (46.5%) had post-RIA changes in the MSGs on follow-up ultrasonography. RIA dose was closely associated with the prevalence of post-RIA changes. Post-RIA changes were more common in the parotid glands (n = 93, 46.0%) than in the submandibular glands (n = 7, 3.5%). Common ultrasonographic findings representing post-RIA changes in MSGs included coarse echotexture, decreased echogenicity, lobulated margin and decreased gland size. CI - Copyright (c) 2015 World Federation for Ultrasound in Medicine & Biology. Published by Elsevier Inc. All rights reserved. FAU - Kim, Dong Wook AU - Kim DW AD - Department of Radiology, Busan Paik Hospital, Inje University College of Medicine, Busan, South Korea. Electronic address: dwultra@lycos.co.kr. LA - eng PT - Controlled Clinical Trial PT - Journal Article DEP - 20150726 PL - England TA - Ultrasound Med Biol JT - Ultrasound in medicine & biology JID - 0410553 RN - 0 (Iodine Radioisotopes) RN - 0 (Radiopharmaceuticals) SB - IM MH - Adult MH - Aged MH - Aged, 80 and over MH - Carcinoma/diagnostic imaging/*radiotherapy MH - Carcinoma, Papillary MH - Female MH - Humans MH - Iodine Radioisotopes/*adverse effects/therapeutic use MH - Male MH - Middle Aged MH - Radiation Injuries/*diagnostic imaging/*etiology MH - Radiopharmaceuticals/adverse effects/therapeutic use MH - Reproducibility of Results MH - Salivary Gland Diseases/*diagnostic imaging/*etiology MH - Sensitivity and Specificity MH - Thyroid Cancer, Papillary MH - Thyroid Neoplasms/diagnostic imaging/*radiotherapy MH - Treatment Outcome MH - Ultrasonography/methods OTO - NOTNLM OT - Computed tomography OT - Major salivary glands OT - Papillary thyroid carcinoma OT - Radioactive iodine ablation OT - Ultrasonography EDAT- 2015/07/29 06:00 MHDA- 2016/06/02 06:00 CRDT- 2015/07/29 06:00 PHST- 2015/04/13 00:00 [received] PHST- 2015/06/08 00:00 [revised] PHST- 2015/06/14 00:00 [accepted] PHST- 2015/07/29 06:00 [entrez] PHST- 2015/07/29 06:00 [pubmed] PHST- 2016/06/02 06:00 [medline] AID - S0301-5629(15)00408-1 [pii] AID - 10.1016/j.ultrasmedbio.2015.06.010 [doi] PST - ppublish SO - Ultrasound Med Biol. 2015 Oct;41(10):2640-5. doi: 10.1016/j.ultrasmedbio.2015.06.010. Epub 2015 Jul 26.