PMID- 26218785 OWN - NLM STAT- MEDLINE DCOM- 20160719 LR - 20220409 IS - 1557-7708 (Electronic) IS - 1075-5535 (Linking) VI - 21 IP - 10 DP - 2015 Oct TI - Effects of Transcutaneous Electrical Acupoint Stimulation on Patients with Stable Chronic Obstructive Pulmonary Disease: A Prospective, Single-Blind, Randomized, Placebo-Controlled Study. PG - 610-6 LID - 10.1089/acm.2014.0284 [doi] AB - OBJECTIVES: To evaluate the clinical effect of transcutaneous electrical nerve stimulation over acupoints (acu-TENS) on patients with stable chronic obstructive pulmonary disease (COPD). DESIGN: Prospective, single-blind, randomized, placebo-controlled study. Settings/Locations: Outpatient center of West China Hospital, Sichuan University. PATIENTS: Fifty patients with stable COPD enrolled in the study. INTERVENTIONS: Patients were randomly assigned to one of two groups: the acu-TENS group (n=25), who underwent acu-TENS over acupoints of bilateral EX-B-1(Dingchuan), BL-13 (Feishu), BL-23 (Shenshu), ST-36 (Zusanli), and the placebo acu-TENS control group (n=25), who had the same electrode placement but no electrical output. Treatments were performed for 40-minute sessions every 2 days for 4 weeks. OUTCOME MEASURES: Lung function (forced expiratory volume in 1 second, percentage predicted (FEV(1)% predicted); forced vital capacity, percentage predicted (FVC% predicted), 6-minute walk distance (6MWD) and oxygen saturation (SpO(2)), COPD assessment test (CAT), and Dyspnea Visual Analogue Scale (DVAS) were assessed before and after the intervention. RESULTS: Compared to control group, FEV(1)% predicted was improved and CAT score was decreased significantly in the acu-TENS group after treatment (p<0.05). The DVAS score decreased significantly in the acu-TENS group (p=0.039), with a slight but insignificant improve in 6MWD, SpO(2), and FVC% predicted after treatment. CONCLUSIONS: Acu-TENS over acupoints of bilateral EX-B-1 (Dingchuan), BL-13 (Feishu), BL-23 (Shenshu), and ST-36 (Zusanli) improved FEV(1)% predicted and reduced DVAS and CAT scores on patients with stable COPD. This may be a novel treatment strategy in COPD. FAU - Liu, Xuemei AU - Liu X AD - 1 Department of Integrated Medicine, West China Hospital of Sichuan University , Chendu, Sichuan, China . FAU - Fan, Tao AU - Fan T AD - 1 Department of Integrated Medicine, West China Hospital of Sichuan University , Chendu, Sichuan, China . FAU - Lan, Ying AU - Lan Y AD - 2 College of Acupuncture and Tuina, Traditional Chinese Medicine of Chengdu University , Chengdu, Sichuan, China . FAU - Dong, Shoujing AU - Dong S AD - 1 Department of Integrated Medicine, West China Hospital of Sichuan University , Chendu, Sichuan, China . FAU - Fu, Juanjuan AU - Fu J AD - 1 Department of Integrated Medicine, West China Hospital of Sichuan University , Chendu, Sichuan, China . FAU - Mao, Bing AU - Mao B AD - 1 Department of Integrated Medicine, West China Hospital of Sichuan University , Chendu, Sichuan, China . LA - eng PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't DEP - 20150728 PL - United States TA - J Altern Complement Med JT - Journal of alternative and complementary medicine (New York, N.Y.) JID - 9508124 RN - S88TT14065 (Oxygen) SB - IM MH - *Acupuncture Points MH - Acupuncture Therapy/*methods MH - Aged MH - Dyspnea/etiology/therapy MH - Female MH - Forced Expiratory Volume MH - Humans MH - Lung/*physiopathology MH - Male MH - Middle Aged MH - Oxygen/metabolism MH - Prospective Studies MH - Pulmonary Disease, Chronic Obstructive/complications/*therapy MH - Respiratory Function Tests MH - Severity of Illness Index MH - Single-Blind Method MH - *Transcutaneous Electric Nerve Stimulation MH - Vital Capacity MH - Walking EDAT- 2015/07/29 06:00 MHDA- 2016/07/20 06:00 CRDT- 2015/07/29 06:00 PHST- 2015/07/29 06:00 [entrez] PHST- 2015/07/29 06:00 [pubmed] PHST- 2016/07/20 06:00 [medline] AID - 10.1089/acm.2014.0284 [doi] PST - ppublish SO - J Altern Complement Med. 2015 Oct;21(10):610-6. doi: 10.1089/acm.2014.0284. Epub 2015 Jul 28.