PMID- 26223005
OWN - NLM
STAT- MEDLINE
DCOM- 20170403
LR  - 20181202
IS  - 1827-1928 (Electronic)
IS  - 0022-4707 (Linking)
VI  - 56
IP  - 11
DP  - 2016 Nov
TI  - Improved end-stage high-intensity performance but similar glycemic responses 
      after waxy barley starch ingestion compared to dextrose in type 1 diabetes.
PG  - 1392-1400
AB  - BACKGROUND: Pre-exercise carbohydrate (CHO) ingestion is an effective strategy 
      for reducing the occurrence of hypoglycemia during or after exercise in 
      individuals with type 1 diabetes (T1DM). The metabolic effects of ingestion of 
      different CHOs for glycemic or performance gains have been under-researched. This 
      study compared metabolic responses and fuel use during sub-maximal and 
      high-intensity performance running following pre-exercise ingestion of waxy 
      barley starch (WBS) or dextrose (DEX) in T1DM. METHODS: Seven participants 
      attended the laboratory on two separate occasions following preliminary testing. 
      On each visit participants consumed either 0.6 g/kg body mass of DEX or WBS 2 
      hours before a 26-minute discontinuous incremental treadmill protocol (4-minute 
      running: 1.5-min rest) finishing at 80+/-4% V̇O2peak followed by a 10-min 
      performance run on a non-motorized treadmill. Capillary blood samples were taken 
      at rest, during and following exercise and analyzed for glucose (BG) and 
      acid-base variables. Data (mean +/- SEM) were analyzed using repeated measures 
      ANOVA (P<0.05). RESULTS: BG reached similar peak values one hour after CHO 
      ingestion and immediate pre-sub-maximal exercise BG were comparable. Resting CHO 
      oxidation was elevated and lipid oxidation lower under WBS (P<0.05). There were 
      no metabolic or cardio-respiratory differences during the sub-maximal exercise 
      (P>0.05). In the final quartile of the performance run, a greater distance was 
      completed under WBS (WBS 323+/-21 vs. DEX 301+/-20 m, P=0.02). CONCLUSIONS: 
      Consumption of WBS demonstrated similar hyperglycemic responses to dextrose 
      ingestion but a greater rate of CHO use at rest. Interestingly, T1DM individuals 
      displayed an improved performance at the latter stages of a high-intensity run 
      test.
FAU - Gray, Benjamin J
AU  - Gray BJ
AD  - Policy, Research and Development Division, Public Health Wales, Cardiff, UK - 
      Benjamin.Gray@wales.nhs.uk.
FAU - Page, Rhydian
AU  - Page R
FAU - Turner, Daniel
AU  - Turner D
FAU - West, Daniel J
AU  - West DJ
FAU - Campbell, Matthew D
AU  - Campbell MD
FAU - Kilduff, Liam P
AU  - Kilduff LP
FAU - Stephens, Jeffrey W
AU  - Stephens JW
FAU - Bain, Stephen C
AU  - Bain SC
FAU - Bracken, Richard M
AU  - Bracken RM
LA  - eng
PT  - Journal Article
DEP - 20150729
PL  - Italy
TA  - J Sports Med Phys Fitness
JT  - The Journal of sports medicine and physical fitness
JID - 0376337
RN  - 0 (Blood Glucose)
RN  - 0 (Dietary Carbohydrates)
RN  - 0 (Hypoglycemic Agents)
RN  - 0 (Insulin)
RN  - IY9XDZ35W2 (Glucose)
SB  - IM
MH  - Adult
MH  - Blood Glucose/*metabolism
MH  - Diabetes Mellitus, Type 1/*blood/*diet therapy/drug therapy
MH  - Dietary Carbohydrates/*administration & dosage
MH  - Female
MH  - Glucose/*administration & dosage
MH  - *Hordeum
MH  - Humans
MH  - Hypoglycemic Agents/administration & dosage
MH  - Insulin/administration & dosage
MH  - Lipid Metabolism
MH  - Male
MH  - Middle Aged
MH  - Running/*physiology
MH  - Young Adult
EDAT- 2015/07/30 06:00
MHDA- 2017/04/04 06:00
CRDT- 2015/07/30 06:00
PHST- 2015/07/30 06:00 [pubmed]
PHST- 2017/04/04 06:00 [medline]
PHST- 2015/07/30 06:00 [entrez]
AID - R40Y9999N00A150138 [pii]
PST - ppublish
SO  - J Sports Med Phys Fitness. 2016 Nov;56(11):1392-1400. Epub 2015 Jul 29.