PMID- 26225981
OWN - NLM
STAT- MEDLINE
DCOM- 20160215
LR  - 20181113
IS  - 1424-8220 (Electronic)
IS  - 1424-8220 (Linking)
VI  - 15
IP  - 8
DP  - 2015 Jul 28
TI  - AlGaN/GaN High Electron Mobility Transistor-Based Biosensor for the Detection of 
      C-Reactive Protein.
PG  - 18416-26
LID - 10.3390/s150818416 [doi]
AB  - In this paper, we propose an AlGaN/GaN high electron mobility transistor 
      (HEMT)-based biosensor for the detection of C-reactive protein (CRP) using a 
      null-balancing circuit. A null-balancing circuit was used to measure the output 
      voltage of the sensor directly. The output voltage of the proposed biosensor was 
      varied by antigen-antibody interactions on the gate surface due to CRP charges. 
      The AlGaN/GaN HFET-based biosensor with null-balancing circuit applied shows that 
      CRP can be detected in a wide range of concentrations, varying from 10 ng/mL to 
      1000 ng/mL. X-ray photoelectron spectroscopy was carried out to verify the 
      immobilization of self-assembled monolayer with Au on the gated region.
FAU - Lee, Hee Ho
AU  - Lee HH
AD  - School of Electronics Engineering, Kyunpook National University, 80 Daehakro, 
      Buk-gu, Daegu 702-701, Korea. heeholee@ee.knu.ac.kr.
FAU - Bae, Myunghan
AU  - Bae M
AD  - School of Electronics Engineering, Kyunpook National University, 80 Daehakro, 
      Buk-gu, Daegu 702-701, Korea. mhbae@ee.knu.ac.kr.
FAU - Jo, Sung-Hyun
AU  - Jo SH
AD  - School of Electronics Engineering, Kyunpook National University, 80 Daehakro, 
      Buk-gu, Daegu 702-701, Korea. shjo@ee.knu.ac.kr.
FAU - Shin, Jang-Kyoo
AU  - Shin JK
AD  - School of Electronics Engineering, Kyunpook National University, 80 Daehakro, 
      Buk-gu, Daegu 702-701, Korea. jkshin@ee.knu.ac.kr.
FAU - Son, Dong Hyeok
AU  - Son DH
AD  - School of Electronics Engineering, Kyunpook National University, 80 Daehakro, 
      Buk-gu, Daegu 702-701, Korea. dhson@ee.knu.ac.kr.
FAU - Won, Chul-Ho
AU  - Won CH
AD  - School of Electronics Engineering, Kyunpook National University, 80 Daehakro, 
      Buk-gu, Daegu 702-701, Korea. chwon@ee.knu.ac.kr.
FAU - Jeong, Hyun-Min
AU  - Jeong HM
AD  - School of Electronics Engineering, Kyunpook National University, 80 Daehakro, 
      Buk-gu, Daegu 702-701, Korea. hmjeong@ee.knu.ac.kr.
FAU - Lee, Jung-Hee
AU  - Lee JH
AD  - School of Electronics Engineering, Kyunpook National University, 80 Daehakro, 
      Buk-gu, Daegu 702-701, Korea. jlee@ee.knu.ac.kr.
FAU - Kang, Shin-Won
AU  - Kang SW
AD  - School of Electronics Engineering, Kyunpook National University, 80 Daehakro, 
      Buk-gu, Daegu 702-701, Korea. swkang@knu.ac.kr.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20150728
PL  - Switzerland
TA  - Sensors (Basel)
JT  - Sensors (Basel, Switzerland)
JID - 101204366
RN  - 0 (Aluminum Compounds)
RN  - 0 (aluminum gallium nitride)
RN  - 1R9CC3P9VL (gallium nitride)
RN  - 9007-41-4 (C-Reactive Protein)
RN  - CH46OC8YV4 (Gallium)
SB  - IM
MH  - Aluminum Compounds/*chemistry
MH  - Biosensing Techniques/*instrumentation
MH  - C-Reactive Protein/*analysis
MH  - Electricity
MH  - *Electrons
MH  - Gallium/*chemistry
MH  - Humans
MH  - Photoelectron Spectroscopy
MH  - *Transistors, Electronic
PMC - PMC4570328
OTO - NOTNLM
OT  - AlGaN/GaN
OT  - CRP
OT  - HEMT
OT  - biosensor
OT  - null-balancing circuit
EDAT- 2015/08/01 06:00
MHDA- 2016/02/16 06:00
PMCR- 2015/07/28
CRDT- 2015/07/31 06:00
PHST- 2015/05/29 00:00 [received]
PHST- 2015/07/21 00:00 [revised]
PHST- 2015/07/24 00:00 [accepted]
PHST- 2015/07/31 06:00 [entrez]
PHST- 2015/08/01 06:00 [pubmed]
PHST- 2016/02/16 06:00 [medline]
PHST- 2015/07/28 00:00 [pmc-release]
AID - s150818416 [pii]
AID - sensors-15-18416 [pii]
AID - 10.3390/s150818416 [doi]
PST - epublish
SO  - Sensors (Basel). 2015 Jul 28;15(8):18416-26. doi: 10.3390/s150818416.