PMID- 26226727
OWN - NLM
STAT- MEDLINE
DCOM- 20150908
LR  - 20221207
IS  - 0042-8450 (Print)
IS  - 0042-8450 (Linking)
VI  - 72
IP  - 6
DP  - 2015 Jun
TI  - Does thrombolytic therapy harm or help in ST elevation myocardial infarction 
      (STEMI) caused by the spontaneous coronary dissection?
PG  - 536-40
AB  - INTRODUCTION: Spontaneous coronary artery dissection (SCAD) is a very rare 
      disease with poor prognosis. It mainly affects young women free of risk factors 
      for coronary artery disease (CAD) and women during the peripartum period. The 
      prognosis for myocardial infarction caused by SCAD is poor, management is often 
      difficult and guidelines still missing. CASE REPORT: We presented a woman with 
      acute myocardial infarction of anterior wall of the left ventricle, caused by 
      spontaneous dissection of medial segment of the left anterior descending coronary 
      artery. We treated the patient with thrombolytic therapy and performed coronary 
      angiography after that. Finally we decided to do nothing more. Two years later we 
      performed coronary angiography again and founded the coronary artery normal. We 
      also analyzed 19 cases publiched from 1996 to 2012 when coronary artery 
      dissection had been treated with thrombolytic agent Analysis revealed only one 
      case of 19, with complication after treating SCAD with thrombolysis. CONCLUSION: 
      Sometimes, regarding myocardial infarction in young women with no risk factors 
      for CAD, especially in young women in peripartum, we should think about SCAD. The 
      presented case, like eight others, demonstrates that good clinical outcomes can 
      be achieved with thrombolysis. In spite of all this, we still need more data to 
      verify that thrombolysis does not have to harm the therapy for SCAD. For the time 
      being thrombolytic therapy could be an option.
FAU - Jovic, Zoran
AU  - Jovic Z
FAU - Obradovic, Slobodan
AU  - Obradovic S
FAU - Djenic, Nemanja
AU  - Djenic N
FAU - Mladenovic, Zorica
AU  - Mladenovic Z
FAU - Djuric, Predrag
AU  - Djuric P
FAU - Spasic, Marijan
AU  - Spasic M
FAU - Tavicovski, Dragan
AU  - Tavicovski D
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - Serbia
TA  - Vojnosanit Pregl
JT  - Vojnosanitetski pregled
JID - 21530700R
SB  - IM
MH  - Aortic Dissection/*complications
MH  - Coronary Aneurysm/*complications
MH  - Coronary Angiography
MH  - Female
MH  - Humans
MH  - Middle Aged
MH  - Myocardial Infarction/*drug therapy/etiology
MH  - *Thrombolytic Therapy
EDAT- 2015/08/01 06:00
MHDA- 2015/09/09 06:00
CRDT- 2015/08/01 06:00
PHST- 2015/08/01 06:00 [entrez]
PHST- 2015/08/01 06:00 [pubmed]
PHST- 2015/09/09 06:00 [medline]
AID - 10.2298/vsp1506536j [doi]
PST - ppublish
SO  - Vojnosanit Pregl. 2015 Jun;72(6):536-40. doi: 10.2298/vsp1506536j.