PMID- 26227078
OWN - NLM
STAT- MEDLINE
DCOM- 20160524
LR  - 20151015
IS  - 1423-0267 (Electronic)
IS  - 0030-3755 (Linking)
VI  - 234
IP  - 3
DP  - 2015
TI  - Effects of Refractive Power on Macular Thickness Measurement Using 
      Spectral-Domain Optical Coherence Tomography.
PG  - 172-6
LID - 10.1159/000437233 [doi]
AB  - PURPOSE: To investigate the effects of refractive power on macular thickness 
      measurements by spectral-domain optical coherence tomography (SD-OCT). SUBJECTS 
      AND METHODS: For this prospective cohort study, a total of 50 eyes from 50 normal 
      subjects with no systemic or ocular disease and no history of ocular surgery were 
      studied from February 2014 to May 2014. We used soft contact lenses with a wide 
      range of diopters to change the refractive power. The macular thickness of 
      uncorrected eyes without contact lenses was measured by SD-OCT, and we compared 
      the findings with the results of subsequent investigations in which macular 
      thickness was measured in the presence of soft contact lenses of different 
      diopters (-8, -4, 0, +4, and +8). We divided the patients into three groups 
      according to the axial length (AL) and analyzed the effect of induced refraction 
      change. The main outcome measure was macular thickness measured by OCT. RESULTS: 
      The average age of the subjects was 28.0 +/- 3.4 years (mean +/- SD), and included 17 
      eyes with normal AL, 18 eyes with mid-range AL, and 15 eyes with long AL. The 
      central macular thickness was 254.5 +/- 17.5 microm for eyes without contact lenses, 
      which was not significantly different from the measurements in the presence of 
      plano contact lenses (254.2 +/- 18.1 microm). Even with soft contact lenses of four 
      different diopters (-8, -4, +4, and +8), central macular thickness (254.4 +/- 16.2, 
      253.7 +/- 17.3, 257.3 +/- 17.9, and 256.9 +/- 17.9 microm, respectively) was not 
      significantly different from that of naked eyes in each group. CONCLUSION: These 
      results suggest that central macular thickness measured by SD-OCT is unaffected 
      by refractive power.
CI  - (c) 2015 S. Karger AG, Basel.
FAU - Lee, Sung Bok
AU  - Lee SB
AD  - Department of Ophthalmology, Chungnam National University College of Medicine, 
      Daejeon, South Korea.
FAU - Shin, Il Hwan
AU  - Shin IH
FAU - Shin, Kyung Sup
AU  - Shin KS
FAU - Jo, Young Joon
AU  - Jo YJ
FAU - Kim, Jung Yeul
AU  - Kim JY
LA  - eng
PT  - Journal Article
DEP - 20150724
PL  - Switzerland
TA  - Ophthalmologica
JT  - Ophthalmologica. Journal international d'ophtalmologie. International journal of 
      ophthalmology. Zeitschrift fur Augenheilkunde
JID - 0054655
SB  - IM
MH  - Adult
MH  - Axial Length, Eye/anatomy & histology
MH  - Female
MH  - Healthy Volunteers
MH  - Humans
MH  - Male
MH  - Prospective Studies
MH  - Refraction, Ocular/*physiology
MH  - Retina/*anatomy & histology
MH  - Tomography, Optical Coherence
EDAT- 2015/08/01 06:00
MHDA- 2016/05/25 06:00
CRDT- 2015/08/01 06:00
PHST- 2015/01/08 00:00 [received]
PHST- 2015/06/25 00:00 [accepted]
PHST- 2015/08/01 06:00 [entrez]
PHST- 2015/08/01 06:00 [pubmed]
PHST- 2016/05/25 06:00 [medline]
AID - 000437233 [pii]
AID - 10.1159/000437233 [doi]
PST - ppublish
SO  - Ophthalmologica. 2015;234(3):172-6. doi: 10.1159/000437233. Epub 2015 Jul 24.