PMID- 26231845
OWN - NLM
STAT- MEDLINE
DCOM- 20160504
LR  - 20181113
IS  - 2047-9980 (Electronic)
IS  - 2047-9980 (Print)
IS  - 2047-9980 (Linking)
VI  - 4
IP  - 8
DP  - 2015 Jul 31
TI  - Publication Speed, Reporting Metrics, and Citation Impact of Cardiovascular 
      Trials Supported by the National Heart, Lung, and Blood Institute.
PG  - e002292
LID - 10.1161/JAHA.115.002292 [doi]
LID - e002292
AB  - BACKGROUND: We previously demonstrated that cardiovascular (CV) trials funded by 
      the National Heart, Lung, and Blood Institute (NHLBI) were more likely to be 
      published in a timely manner and receive high raw citation counts if they focused 
      on clinical endpoints. We did not examine the metrics of trial reports, and our 
      citation measures were limited by failure to account for topic-related citation 
      behaviors. METHODS AND RESULTS: Of 244 CV trials completed between 2000 and 2011, 
      we identified 184 whose main results were published by August 20, 2014. One 
      investigator who was blinded to rapidity of publication and citation data read 
      each publication and characterized it according to modified Delphi criteria. 
      There were 46 trials (25%) that had Delphi scores of 8 or 9 (of a possible 9); 
      these trials published faster (median time from trial completion to publication, 
      12.6 [interquartile range IQR, 6.7 to 23.3] vs. 21.8 [IQR, 12.1 to 34.9] 
      months; P<0.01). They also had better normalized citation impact (median citation 
      percentile for topic and date of publication, with 0 best and 100 worst, 1.92 
      [IQR, 0.64 to 7.83] vs. 8.41 [IQR, 1.80 to 24.75]; P=0.002). By random forest 
      regression, we found that the 3 most important predictors of normalized citation 
      percentile values were total costs, intention-to-treat analyses (as a modified 
      Delphi quality measure), and focus on clinical (not surrogate) endpoints. 
      CONCLUSIONS: NHLBI CV trials were more likely to publish results quickly and 
      yield higher topic-normalized citation impact if they reported results according 
      to well-defined metrics, along with focus on clinical endpoints.
CI  - (c) 2015 The Authors. Published on behalf of the American Heart Association, Inc., 
      by Wiley Blackwell.
FAU - Gordon, David
AU  - Gordon D
AD  - Division of Cardiovascular Sciences (DCVS), National Heart, Lung, and Blood 
      Institute (NHLBI), Bethesda, MD (D.G., K.C.A., M.L.).
FAU - Cooper-Arnold, Katharine
AU  - Cooper-Arnold K
AD  - Division of Cardiovascular Sciences (DCVS), National Heart, Lung, and Blood 
      Institute (NHLBI), Bethesda, MD (D.G., K.C.A., M.L.).
FAU - Lauer, Michael
AU  - Lauer M
AD  - Division of Cardiovascular Sciences (DCVS), National Heart, Lung, and Blood 
      Institute (NHLBI), Bethesda, MD (D.G., K.C.A., M.L.).
LA  - eng
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
DEP - 20150731
PL  - England
TA  - J Am Heart Assoc
JT  - Journal of the American Heart Association
JID - 101580524
SB  - IM
MH  - Bibliometrics
MH  - Cardiology/economics/*statistics & numerical data
MH  - Cardiovascular Diseases/diagnosis/economics/*therapy
MH  - Delphi Technique
MH  - Endpoint Determination
MH  - Humans
MH  - Intention to Treat Analysis
MH  - Journal Impact Factor
MH  - National Heart, Lung, and Blood Institute (U.S.)/economics/*statistics & 
      numerical data
MH  - Periodicals as Topic/*statistics & numerical data
MH  - Publishing/*statistics & numerical data
MH  - Randomized Controlled Trials as Topic/economics/*statistics & numerical data
MH  - Research Design/*statistics & numerical data
MH  - Research Support as Topic/economics/*statistics & numerical data
MH  - Time Factors
MH  - Treatment Outcome
MH  - United States
PMC - PMC4599480
OTO - NOTNLM
OT  - bibliometrics
OT  - citation
OT  - public policy
OT  - randomized, controlled trial
OT  - research funding
EDAT- 2015/08/02 06:00
MHDA- 2016/05/05 06:00
PMCR- 2015/08/01
CRDT- 2015/08/02 06:00
PHST- 2015/08/02 06:00 [entrez]
PHST- 2015/08/02 06:00 [pubmed]
PHST- 2016/05/05 06:00 [medline]
PHST- 2015/08/01 00:00 [pmc-release]
AID - JAHA.115.002292 [pii]
AID - 10.1161/JAHA.115.002292 [doi]
PST - epublish
SO  - J Am Heart Assoc. 2015 Jul 31;4(8):e002292. doi: 10.1161/JAHA.115.002292.