PMID- 26233514
OWN - NLM
STAT- MEDLINE
DCOM- 20170721
LR  - 20170721
IS  - 2174-2030 (Electronic)
IS  - 0870-2551 (Linking)
VI  - 34
IP  - 9
DP  - 2015 Sep
TI  - [Percutaneous treatment of mitral valve regurgitation: Initial experience with 
      the MitraClip device].
PG  - 515-24
LID - S0870-2551(15)00133-X [pii]
LID - 10.1016/j.repc.2015.04.004 [doi]
AB  - INTRODUCTION: Mitral regurgitation (MR) is the most common valvular disease and 
      has recently become the target of a number of percutaneous approaches. The 
      MitraClip is virtually the only device for which there is considerable 
      experience, with more than 20,000 procedures performed worldwide. OBJECTIVE: To 
      describe our initial experience of the percutaneous treatment of MR with the 
      MitraClip device. METHODS: We describe the first six MitraClip cases performed in 
      this institution (mean age 58.5 +/- 13.1 years), with functional MR grade 4+ and 
      New York Heart Association (NYHA) heart failure class III or IV (n=3), with a 
      mean follow-up of 290 +/- 145 days. RESULTS: Procedural success (MR </= 2+) was 100%. 
      Total procedure time was 115.8 +/- 23.7 min, with no in-hospital adverse events and 
      discharge between the fourth and eighth day, and consistent improvement in the 
      six-minute walk test (329.8 +/- 98.42 vs. 385.33 +/- 106.95 m) and in NYHA class 
      (three patients improved by two NYHA classes). During follow-up there were two 
      deaths, in two of the four patients who had been initially considered for heart 
      transplantation. CONCLUSION: In patients with functional MR the MitraClip 
      procedure is safe, with both a high implantation and immediate in-hospital 
      success rate. A longer follow-up suggests that the clinical benefit decreases or 
      disappears completely in patients with more advanced heart disease, namely those 
      denied transplantation or on the heart transplant waiting list.
CI  - Copyright (c) 2014 Sociedade Portuguesa de Cardiologia. Published by Elsevier 
      Espana. All rights reserved.
FAU - Cacela, Duarte
AU  - Cacela D
AD  - Servico de Cardiologia, Hospital S. Marta, Centro Hospitalar Lisboa Central, 
      Lisboa, Portugal. Electronic address: dcacela@hotmail.com.
FAU - Fiarresga, Antonio
AU  - Fiarresga A
AD  - Servico de Cardiologia, Hospital S. Marta, Centro Hospitalar Lisboa Central, 
      Lisboa, Portugal.
FAU - Branco, Luisa
AU  - Branco L
AD  - Servico de Cardiologia, Hospital S. Marta, Centro Hospitalar Lisboa Central, 
      Lisboa, Portugal.
FAU - Galrinho, Ana
AU  - Galrinho A
AD  - Servico de Cardiologia, Hospital S. Marta, Centro Hospitalar Lisboa Central, 
      Lisboa, Portugal.
FAU - Rio, Pedro
AU  - Rio P
AD  - Servico de Cardiologia, Hospital S. Marta, Centro Hospitalar Lisboa Central, 
      Lisboa, Portugal.
FAU - Selas, Mafalda
AU  - Selas M
AD  - Servico de Cardiologia, Hospital S. Marta, Centro Hospitalar Lisboa Central, 
      Lisboa, Portugal.
FAU - Ferreira, Rui
AU  - Ferreira R
AD  - Servico de Cardiologia, Hospital S. Marta, Centro Hospitalar Lisboa Central, 
      Lisboa, Portugal.
LA  - por
PT  - Journal Article
TT  - Terapeutica percutanea da insuficiencia mitral: experiencia inicial com o 
      dispositivo MitraClip.
DEP - 20150729
PL  - Portugal
TA  - Rev Port Cardiol
JT  - Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de 
      Cardiologia = Portuguese journal of cardiology : an official journal of the 
      Portuguese Society of Cardiology
JID - 8710716
SB  - IM
MH  - Aged, 80 and over
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Mitral Valve Insufficiency/*surgery
MH  - *Prostheses and Implants
MH  - Prosthesis Design
MH  - Prosthesis Implantation/methods
OTO - NOTNLM
OT  - Functional mitral regurgitation
OT  - Insuficiencia mitral
OT  - Insuficiencia mitral funcional
OT  - MitraClip
OT  - Mitral regurgitation
OT  - Percutaneous mitral valve repair
OT  - Reparacao percutanea da valvula mitral
EDAT- 2015/08/04 06:00
MHDA- 2017/07/22 06:00
CRDT- 2015/08/03 06:00
PHST- 2014/09/23 00:00 [received]
PHST- 2015/01/24 00:00 [revised]
PHST- 2015/04/08 00:00 [accepted]
PHST- 2015/08/03 06:00 [entrez]
PHST- 2015/08/04 06:00 [pubmed]
PHST- 2017/07/22 06:00 [medline]
AID - S0870-2551(15)00133-X [pii]
AID - 10.1016/j.repc.2015.04.004 [doi]
PST - ppublish
SO  - Rev Port Cardiol. 2015 Sep;34(9):515-24. doi: 10.1016/j.repc.2015.04.004. Epub 
      2015 Jul 29.