PMID- 26236224
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20150803
LR  - 20200929
IS  - 1662-5161 (Print)
IS  - 1662-5161 (Electronic)
IS  - 1662-5161 (Linking)
VI  - 9
DP  - 2015
TI  - Predicting individual brain maturity using dynamic functional connectivity.
PG  - 418
LID - 10.3389/fnhum.2015.00418 [doi]
LID - 418
AB  - Neuroimaging-based functional connectivity (FC) analyses have revealed 
      significant developmental trends in specific intrinsic connectivity networks 
      linked to cognitive and behavioral maturation. However, knowledge of how brain 
      functional maturation is associated with FC dynamics at rest is limited. Here, we 
      examined age-related differences in the temporal variability of FC dynamics with 
      data publicly released by the Nathan Kline Institute (NKI; n = 183, ages 7-30) 
      and showed that dynamic inter-region interactions can be used to accurately 
      predict individual brain maturity across development. Furthermore, we identified 
      a significant age-dependent trend underlying dynamic inter-network FC, including 
      increasing variability of the connections between the visual network, default 
      mode network (DMN) and cerebellum as well as within the cerebellum and DMN and 
      decreasing variability within the cerebellum and between the cerebellum and DMN 
      as well as the cingulo-opercular network. Overall, the results suggested 
      significant developmental changes in dynamic inter-network interaction, which may 
      shed new light on the functional organization of typical developmental brains.
FAU - Qin, Jian
AU  - Qin J
AD  - College of Mechatronics and Automation, National University of Defense 
      Technology, Changsha China.
FAU - Chen, Shan-Guang
AU  - Chen SG
AD  - National Key Laboratory of Human Factors Engineering, China Astronaut Research 
      and Training Center, Beijing China.
FAU - Hu, Dewen
AU  - Hu D
AD  - College of Mechatronics and Automation, National University of Defense 
      Technology, Changsha China.
FAU - Zeng, Ling-Li
AU  - Zeng LL
AD  - College of Mechatronics and Automation, National University of Defense 
      Technology, Changsha China.
FAU - Fan, Yi-Ming
AU  - Fan YM
AD  - College of Mechatronics and Automation, National University of Defense 
      Technology, Changsha China.
FAU - Chen, Xiao-Ping
AU  - Chen XP
AD  - National Key Laboratory of Human Factors Engineering, China Astronaut Research 
      and Training Center, Beijing China.
FAU - Shen, Hui
AU  - Shen H
AD  - College of Mechatronics and Automation, National University of Defense 
      Technology, Changsha China.
LA  - eng
PT  - Journal Article
DEP - 20150716
PL  - Switzerland
TA  - Front Hum Neurosci
JT  - Frontiers in human neuroscience
JID - 101477954
PMC - PMC4503925
OTO - NOTNLM
OT  - development
OT  - fMRI
OT  - functional connectivity
OT  - low-frequency fluctuation
OT  - multivariate pattern analysis
EDAT- 2015/08/04 06:00
MHDA- 2015/08/04 06:01
PMCR- 2015/01/01
CRDT- 2015/08/04 06:00
PHST- 2015/05/09 00:00 [received]
PHST- 2015/07/06 00:00 [accepted]
PHST- 2015/08/04 06:00 [entrez]
PHST- 2015/08/04 06:00 [pubmed]
PHST- 2015/08/04 06:01 [medline]
PHST- 2015/01/01 00:00 [pmc-release]
AID - 10.3389/fnhum.2015.00418 [doi]
PST - epublish
SO  - Front Hum Neurosci. 2015 Jul 16;9:418. doi: 10.3389/fnhum.2015.00418. eCollection 
      2015.