PMID- 26236315
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20150803
LR  - 20220131
IS  - 1664-3224 (Print)
IS  - 1664-3224 (Electronic)
IS  - 1664-3224 (Linking)
VI  - 6
DP  - 2015
TI  - Cross-Presentation of Cell-Associated Antigens by MHC Class I in Dendritic Cell 
      Subsets.
PG  - 363
LID - 10.3389/fimmu.2015.00363 [doi]
LID - 363
AB  - Dendritic cells (DCs) have the unique ability to pick up dead cells carrying 
      antigens in tissue and migrate to the lymph nodes where they can cross-present 
      cell-associated antigens by MHC class I to CD8(+) T cells. There is strong in 
      vivo evidence that the mouse XCR1(+) DCs subset acts as a key player in this 
      process. The intracellular processes underlying cross-presentation remain 
      controversial and several pathways have been proposed. Indeed, a wide number of 
      studies have addressed the cellular process of cross-presentation in vitro using 
      a variety of sources of antigen and antigen-presenting cells. Here, we review the 
      in vivo and in vitro evidence supporting the current mechanistic models and 
      disscuss their physiological relevance to the cross-presentation of 
      cell-associated antigens by DCs subsets.
FAU - Gutierrez-Martinez, Enric
AU  - Gutierrez-Martinez E
AD  - Laboratory of Phagocyte Immunobiology, Peter Gorer Department of Immunobiology, 
      CMCBI, King's College London , London , UK.
FAU - Planes, Remi
AU  - Planes R
AD  - Laboratory of Phagocyte Immunobiology, Peter Gorer Department of Immunobiology, 
      CMCBI, King's College London , London , UK.
FAU - Anselmi, Giorgio
AU  - Anselmi G
AD  - Laboratory of Phagocyte Immunobiology, Peter Gorer Department of Immunobiology, 
      CMCBI, King's College London , London , UK.
FAU - Reynolds, Matthew
AU  - Reynolds M
AD  - Laboratory of Phagocyte Immunobiology, Peter Gorer Department of Immunobiology, 
      CMCBI, King's College London , London , UK.
FAU - Menezes, Shinelle
AU  - Menezes S
AD  - Laboratory of Phagocyte Immunobiology, Peter Gorer Department of Immunobiology, 
      CMCBI, King's College London , London , UK.
FAU - Adiko, Aime Cezaire
AU  - Adiko AC
AD  - Laboratory of Phagocyte Immunobiology, Peter Gorer Department of Immunobiology, 
      Centre for Molecular & Cellular Biology of Inflammation (CMCBI), King's College 
      London , Paris , France ; Sorbonne Paris Cite, Universite Paris Diderot , Paris , 
      France.
FAU - Saveanu, Loredana
AU  - Saveanu L
AD  - Laboratory of Phagocyte Immunobiology, Peter Gorer Department of Immunobiology, 
      Centre for Molecular & Cellular Biology of Inflammation (CMCBI), King's College 
      London , Paris , France ; Sorbonne Paris Cite, Universite Paris Diderot , Paris , 
      France.
FAU - Guermonprez, Pierre
AU  - Guermonprez P
AD  - Laboratory of Phagocyte Immunobiology, Peter Gorer Department of Immunobiology, 
      CMCBI, King's College London , London , UK.
LA  - eng
GR  - MR/K01241X/1/MRC_/Medical Research Council/United Kingdom
PT  - Journal Article
PT  - Review
DEP - 20150717
PL  - Switzerland
TA  - Front Immunol
JT  - Frontiers in immunology
JID - 101560960
PMC - PMC4505393
OTO - NOTNLM
OT  - MHC class I
OT  - antigen processing
OT  - cross-presentation
OT  - cross-priming
OT  - dendritic cells
OT  - phagocytosis
EDAT- 2015/08/04 06:00
MHDA- 2015/08/04 06:01
PMCR- 2015/01/01
CRDT- 2015/08/04 06:00
PHST- 2015/04/02 00:00 [received]
PHST- 2015/07/05 00:00 [accepted]
PHST- 2015/08/04 06:00 [entrez]
PHST- 2015/08/04 06:00 [pubmed]
PHST- 2015/08/04 06:01 [medline]
PHST- 2015/01/01 00:00 [pmc-release]
AID - 10.3389/fimmu.2015.00363 [doi]
PST - epublish
SO  - Front Immunol. 2015 Jul 17;6:363. doi: 10.3389/fimmu.2015.00363. eCollection 
      2015.