PMID- 26237828
OWN - NLM
STAT- MEDLINE
DCOM- 20150908
LR  - 20191027
IS  - 0255-2922 (Print)
IS  - 0255-2922 (Linking)
VI  - 35
IP  - 3
DP  - 2015 Jun
TI  - Effects on type 2 diabetes complicated with pulmonary tuberculosis: regiment of 
      insulin, isoniazid, rifampicin, pyrazinamide and ethambutol versus the regiment 
      plus Qi-boosting and Yin-nourishing decoction of Traditional Chinese Medicine.
PG  - 260-5
AB  - OBJECTIVE: To observe the clinical effect on type 2 diabetes mellitus (T2DM) 
      complicated with pulmonary tuberculosis (TB) of insulin, isoniazid, rifampicin, 
      pyrazinamide and ethambutol (conventional medication) administered together with 
      Qi-boosting and Yin-nourishing decoction derived from Traditional Chinese 
      Medicine (TCM). METHODS: A total of 60 patients with T2DM complicated with 
      pulmonary TB were randomly and equally divided into positive control group and 
      treatment group. The control group was treated with Western conventional regiment 
      (WCR): insulin, isoniazid, rifampicin, pyrazinamide, and ethambutol, whereas the 
      treatment group was given both WCR and Qi-boosting and Yin-nourishing decoction 
      prepared from TCM. RESULTS: After the treatment, 20 (66.7%) and 11 (36.7%) cases 
      showed sputum bacteria negative conversion in the WCR plus TCM group and WCM 
      group respectively (P < 0.05). A total of 25 (83.3%) and 18 (60%) cases showed 
      improvement in lung lesion in the WCR plus TCM group and WCM group respectively 
      (P < 0.05). Compared with WCR group, fasting plasma glucose and 2-hour 
      postprandial blood glucose levels in the WCR plus TCM group significantly 
      decreased (P < 0.05 and P < 0.01, respectively). CONCLUSION: Qi-boosting and 
      Yin-nourishing decoction combined with the Western medication showed better 
      curative effect in treating T2DM complicated with pulmonary TB compared with the 
      group using the conventional Western Medicine alone.
FAU - Shi, Guangcan
AU  - Shi G
FAU - Zhang, Ligong
AU  - Zhang L
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Randomized Controlled Trial
PT  - Research Support, Non-U.S. Gov't
PL  - China
TA  - J Tradit Chin Med
JT  - Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan
JID - 8211546
RN  - 0 (Antitubercular Agents)
RN  - 0 (Drugs, Chinese Herbal)
RN  - 0 (Hypoglycemic Agents)
RN  - 0 (Insulin)
RN  - 2KNI5N06TI (Pyrazinamide)
RN  - 8G167061QZ (Ethambutol)
RN  - V83O1VOZ8L (Isoniazid)
RN  - VJT6J7R4TR (Rifampin)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Antitubercular Agents/*administration & dosage
MH  - Diabetes Mellitus, Type 2/complications/*drug therapy/metabolism
MH  - Drug Therapy, Combination
MH  - Drugs, Chinese Herbal/*administration & dosage
MH  - Ethambutol/administration & dosage
MH  - Female
MH  - Humans
MH  - Hypoglycemic Agents/*administration & dosage
MH  - Insulin/administration & dosage
MH  - Isoniazid/administration & dosage
MH  - Pyrazinamide/administration & dosage
MH  - Rifampin/administration & dosage
MH  - Tuberculosis, Pulmonary/complications/*drug therapy/metabolism
EDAT- 2015/08/05 06:00
MHDA- 2015/09/09 06:00
CRDT- 2015/08/05 06:00
PHST- 2015/08/05 06:00 [entrez]
PHST- 2015/08/05 06:00 [pubmed]
PHST- 2015/09/09 06:00 [medline]
AID - 10.1016/s0254-6272(15)30095-9 [doi]
PST - ppublish
SO  - J Tradit Chin Med. 2015 Jun;35(3):260-5. doi: 10.1016/s0254-6272(15)30095-9.