PMID- 26239767
OWN - NLM
STAT- MEDLINE
DCOM- 20160405
LR  - 20181202
IS  - 1872-7123 (Electronic)
IS  - 0165-1781 (Linking)
VI  - 229
IP  - 1-2
DP  - 2015 Sep 30
TI  - Effects of a single bout of maximal aerobic exercise on BDNF in bipolar disorder: 
      A gender-based response.
PG  - 57-62
LID - S0165-1781(15)00532-6 [pii]
LID - 10.1016/j.psychres.2015.07.072 [doi]
AB  - Acute exercise increases brain-derived neurotrophic factor (BDNF) serum levels in 
      majorly depressed and anxious patients. However, to the best of our knowledge, no 
      study has evaluated the acute effects of exercise on BDNF serum levels in Bipolar 
      Disorder (BD). The objective of the present study was to evaluate the peripheral 
      BDNF serum response to a single maximum session of exercise in BD participants 
      and age- and gender-matched healthy participants. BD participants (n=18) and age- 
      and gender-matched healthy participants (n=18) were recruited to perform a single 
      bout of maximal exercise on a cycle ergometer. Blood samples were collected prior 
      to and immediately after the exercise protocol. There was a significant group 
      effect and a significant group x time x gender interaction. BD participants 
      presented significantly higher BDNF serum levels when compared to their healthy 
      control counterparts. Exercise increases the BDNF levels of BD women, but not 
      men.
CI  - Copyright (c) 2015. Published by Elsevier Ireland Ltd.
FAU - Schuch, Felipe Barreto
AU  - Schuch FB
AD  - Hospital de Clinicas de Porto Alegre, Porto Alegre, Brazil; Programa de 
      Pos-Graduacao em Ciencias Medicas: Psiquiatria, Universidade Federal do Rio 
      Grande do Sul, Porto Alegre, Brazil; Laboratorio de Pesquisa do Exercicio, Escola 
      Superior de Educacao Fisica, Universidade Federal do Rio Grande do Sul, Porto 
      Alegre, Brazil. Electronic address: felipe.schuch@ufrgs.br.
FAU - da Silveira, Leonardo Evangelista
AU  - da Silveira LE
AD  - Hospital de Clinicas de Porto Alegre, Porto Alegre, Brazil; Programa de 
      Pos-Graduacao em Ciencias Medicas: Psiquiatria, Universidade Federal do Rio 
      Grande do Sul, Porto Alegre, Brazil; Laboratory of Molecular Psychiatry, and INCT 
      for Translational Medicine, Porto Alegre, Brazil.
FAU - de Zeni, Tais Cardoso
AU  - de Zeni TC
AD  - Hospital de Clinicas de Porto Alegre, Porto Alegre, Brazil; Laboratorio de 
      Pesquisa do Exercicio, Escola Superior de Educacao Fisica, Universidade Federal 
      do Rio Grande do Sul, Porto Alegre, Brazil.
FAU - da Silva, Diana Perin
AU  - da Silva DP
AD  - Laboratorio de Pesquisa do Exercicio, Escola Superior de Educacao Fisica, 
      Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
FAU - Wollenhaupt-Aguiar, Bianca
AU  - Wollenhaupt-Aguiar B
AD  - Hospital de Clinicas de Porto Alegre, Porto Alegre, Brazil; Programa de 
      Pos-Graduacao em Ciencias Medicas: Psiquiatria, Universidade Federal do Rio 
      Grande do Sul, Porto Alegre, Brazil; Laboratory of Molecular Psychiatry, and INCT 
      for Translational Medicine, Porto Alegre, Brazil.
FAU - Ferrari, Pamela
AU  - Ferrari P
AD  - Hospital de Clinicas de Porto Alegre, Porto Alegre, Brazil; Laboratory of 
      Molecular Psychiatry, and INCT for Translational Medicine, Porto Alegre, Brazil.
FAU - Reischak-Oliveira, Alvaro
AU  - Reischak-Oliveira A
AD  - Laboratorio de Pesquisa do Exercicio, Escola Superior de Educacao Fisica, 
      Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
FAU - Kapczinski, Flavio
AU  - Kapczinski F
AD  - Hospital de Clinicas de Porto Alegre, Porto Alegre, Brazil; Programa de 
      Pos-Graduacao em Ciencias Medicas: Psiquiatria, Universidade Federal do Rio 
      Grande do Sul, Porto Alegre, Brazil; Laboratory of Molecular Psychiatry, and INCT 
      for Translational Medicine, Porto Alegre, Brazil.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20150728
PL  - Ireland
TA  - Psychiatry Res
JT  - Psychiatry research
JID - 7911385
RN  - 0 (Brain-Derived Neurotrophic Factor)
RN  - 7171WSG8A2 (BDNF protein, human)
SB  - IM
MH  - Adult
MH  - Bipolar Disorder/*blood/*psychology
MH  - Brain-Derived Neurotrophic Factor/*blood
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Reference Values
MH  - Sex Factors
OTO - NOTNLM
OT  - Bipolar disorders
OT  - Brain-derived neurotrophic factor
OT  - Exercise
OT  - Neurogenesis
EDAT- 2015/08/05 06:00
MHDA- 2016/04/06 06:00
CRDT- 2015/08/05 06:00
PHST- 2014/12/27 00:00 [received]
PHST- 2015/07/06 00:00 [revised]
PHST- 2015/07/26 00:00 [accepted]
PHST- 2015/08/05 06:00 [entrez]
PHST- 2015/08/05 06:00 [pubmed]
PHST- 2016/04/06 06:00 [medline]
AID - S0165-1781(15)00532-6 [pii]
AID - 10.1016/j.psychres.2015.07.072 [doi]
PST - ppublish
SO  - Psychiatry Res. 2015 Sep 30;229(1-2):57-62. doi: 10.1016/j.psychres.2015.07.072. 
      Epub 2015 Jul 28.