PMID- 26240392
OWN - NLM
STAT- MEDLINE
DCOM- 20151110
LR  - 20200220
IS  - 0032-5791 (Print)
IS  - 0032-5791 (Linking)
VI  - 94
IP  - 10
DP  - 2015 Oct
TI  - Eradication of Mycoplasma synoviae from a multi-age broiler breeder farm using 
      antibiotics therapy.
PG  - 2364-8
LID - 10.3382/ps/pev232 [doi]
AB  - Mycoplasma synoviae (MS) is a common respiratory pathogen in the poultry 
      industry. Eradication of MS from broiler breeder flocks is important for reducing 
      economic losses caused by MS-associated diseases on broiler farms. An outbreak of 
      MS infection was detected on a multi-age Korean broiler breeder farm that 
      implements a flock replacement program every 3 to 6 months and uses A-type cages. 
      Continuous administration of tilmicosin after 2 rounds of intensive antibiotics 
      treatment with chlortetracycline, doxycycline, and enrofloxacin reduced MS 
      shedding from the MS-positive flocks and eventually eradicated MS from the farm. 
      Flock 3 was the last MS-positive flock by both PCR and enzyme-linked 
      immunosorbent assay (ELISA), while flocks introduced to the farm after flock 3 
      were MS-negative by both PCR and ELISA at the time of depletion. This is the 
      first report of successful eradication of MS from a multi-age broiler breeder 
      farm using continuous antibiotic treatments.
CI  - (c) 2015 Poultry Science Association Inc.
FAU - Hong, Young-Ho
AU  - Hong YH
AD  - Aviagen Inc. Cummings Research Park, 920 Explorer Boulevard NW, Huntsville, AL, 
      35806, USA College of Veterinary Medicine, Konkuk University, 1 Hwayang-dong, 
      Gwangjin-gu, Seoul, Korea.
FAU - Kwon, Ji-Seon
AU  - Kwon JS
AD  - College of Veterinary Medicine, Konkuk University, 1 Hwayang-dong, Gwangjin-gu, 
      Seoul, Korea.
FAU - Lee, Hyun-Jeong
AU  - Lee HJ
AD  - College of Veterinary Medicine, Konkuk University, 1 Hwayang-dong, Gwangjin-gu, 
      Seoul, Korea.
FAU - Song, Chang-Seon
AU  - Song CS
AD  - College of Veterinary Medicine, Konkuk University, 1 Hwayang-dong, Gwangjin-gu, 
      Seoul, Korea.
FAU - Lee, Sang-Won
AU  - Lee SW
AD  - College of Veterinary Medicine, Konkuk University, 1 Hwayang-dong, Gwangjin-gu, 
      Seoul, Korea odssey@konkuk.ac.kr.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20150803
PL  - England
TA  - Poult Sci
JT  - Poultry science
JID - 0401150
RN  - 0 (Anti-Bacterial Agents)
SB  - IM
MH  - Animal Husbandry/*methods
MH  - Animals
MH  - Anti-Bacterial Agents/*pharmacology/*therapeutic use
MH  - *Chickens
MH  - Enzyme-Linked Immunosorbent Assay/veterinary
MH  - Female
MH  - Mycoplasma Infections/drug therapy/microbiology/*veterinary
MH  - Mycoplasma synoviae/*drug effects
MH  - Polymerase Chain Reaction/veterinary
MH  - Poultry Diseases/*drug therapy/microbiology
MH  - Republic of Korea
EDAT- 2015/08/05 06:00
MHDA- 2015/11/11 06:00
CRDT- 2015/08/05 06:00
PHST- 2015/06/23 00:00 [accepted]
PHST- 2015/03/31 00:00 [received]
PHST- 2015/08/05 06:00 [entrez]
PHST- 2015/08/05 06:00 [pubmed]
PHST- 2015/11/11 06:00 [medline]
AID - S0032-5791(19)31943-1 [pii]
AID - 10.3382/ps/pev232 [doi]
PST - ppublish
SO  - Poult Sci. 2015 Oct;94(10):2364-8. doi: 10.3382/ps/pev232. Epub 2015 Aug 3.