PMID- 26244599
OWN - NLM
STAT- MEDLINE
DCOM- 20160706
LR  - 20150806
IS  - 1715-5320 (Electronic)
IS  - 1715-5312 (Linking)
VI  - 40
IP  - 8
DP  - 2015 Aug
TI  - Differential acute effects of carbohydrate- and protein-rich drinks compared with 
      water on cardiac output during rest and exercise in healthy young men.
PG  - 803-10
LID - 10.1139/apnm-2014-0358 [doi]
AB  - The acute effects of drinks rich in protein (PRO) versus carbohydrate (CHO) on 
      cardiovascular hemodynamics and reactivity are uncertain. A randomized crossover 
      design was used to compare 400-mL isoenergetic (1.1 MJ) drinks containing whey 
      protein (PRO; 44 g) or carbohydrate (CHO; 57 g) versus 400 mL of water in 14 
      healthy men. The primary and secondary outcomes were changes in cardiac output, 
      blood pressure, systemic vascular resistance (SVR) and digital volume pulse 
      measured prior to and 30 min following consumption at rest, during 12 min of 
      multi-stage bicycle ergometry, and 15 min postexercise. The mean change (95% 
      confidence interval (CI)) in resting cardiac output at 30 min was greater for CHO 
      than for PRO or water: 0.7 (0.4 to 1.0), 0.1 (-0.2 to 0.40), and 0.0 (-0.3 to 
      0.3) L/min (P < 0.001), respectively; the higher cardiac output following CHO was 
      accompanied by an increase in stroke volume and a lower SVR. The mean increments 
      (95% CI) in cardiac output during exercise were CHO 4.7 (4.4 to 5.0), PRO 4.9 
      (4.6 to 5.2), and water 4.6 (4.3 to 4.9) L/min with the difference between PRO 
      versus water being significant (P < 0.025). There were no other statistically 
      significant differences. In summary, a CHO-rich drink increased cardiac output 
      and lowered SVR in the resting state compared with a PRO-rich drink or water but 
      the effect size of changes in these variables did not differ during or after 
      exercise between CHO and PRO. Neither protein nor carbohydrate affected blood 
      pressure reactivity to exercise.
FAU - Rontoyanni, Victoria G
AU  - Rontoyanni VG
AD  - Diabetes and Nutritional Sciences Division, School of Medicine, King's College 
      London, Franklin-Wilkins Building, 150 Stamford Street, London, SE1 9NH, UK.
AD  - Diabetes and Nutritional Sciences Division, School of Medicine, King's College 
      London, Franklin-Wilkins Building, 150 Stamford Street, London, SE1 9NH, UK.
FAU - Werner, Kristin
AU  - Werner K
AD  - Diabetes and Nutritional Sciences Division, School of Medicine, King's College 
      London, Franklin-Wilkins Building, 150 Stamford Street, London, SE1 9NH, UK.
AD  - Diabetes and Nutritional Sciences Division, School of Medicine, King's College 
      London, Franklin-Wilkins Building, 150 Stamford Street, London, SE1 9NH, UK.
FAU - Sanders, Thomas A B
AU  - Sanders TA
AD  - Diabetes and Nutritional Sciences Division, School of Medicine, King's College 
      London, Franklin-Wilkins Building, 150 Stamford Street, London, SE1 9NH, UK.
AD  - Diabetes and Nutritional Sciences Division, School of Medicine, King's College 
      London, Franklin-Wilkins Building, 150 Stamford Street, London, SE1 9NH, UK.
FAU - Hall, Wendy L
AU  - Hall WL
AD  - Diabetes and Nutritional Sciences Division, School of Medicine, King's College 
      London, Franklin-Wilkins Building, 150 Stamford Street, London, SE1 9NH, UK.
AD  - Diabetes and Nutritional Sciences Division, School of Medicine, King's College 
      London, Franklin-Wilkins Building, 150 Stamford Street, London, SE1 9NH, UK.
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Canada
TA  - Appl Physiol Nutr Metab
JT  - Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition 
      et metabolisme
JID - 101264333
RN  - 0 (Dietary Carbohydrates)
RN  - 0 (Dietary Proteins)
RN  - 059QF0KO0R (Water)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - *Beverages
MH  - Cardiac Output/*drug effects
MH  - Dietary Carbohydrates/*pharmacology
MH  - Dietary Proteins/*pharmacology
MH  - Exercise/*physiology
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Reference Values
MH  - Rest/*physiology
MH  - Water/*administration & dosage
MH  - Young Adult
OTO - NOTNLM
OT  - blood pressure
OT  - carbohydrate
OT  - cardiac output
OT  - cardiovascular reactivity
OT  - debit cardiaque
OT  - exercice physique
OT  - exercise
OT  - pression sanguine
OT  - protein
OT  - proteines
OT  - reactivite cardiovasculaire
OT  - sucres
EDAT- 2015/08/06 06:00
MHDA- 2016/07/07 06:00
CRDT- 2015/08/06 06:00
PHST- 2015/08/06 06:00 [entrez]
PHST- 2015/08/06 06:00 [pubmed]
PHST- 2016/07/07 06:00 [medline]
AID - 10.1139/apnm-2014-0358 [doi]
PST - ppublish
SO  - Appl Physiol Nutr Metab. 2015 Aug;40(8):803-10. doi: 10.1139/apnm-2014-0358.